[{"orgOrder":0,"company":"Nektar Therapeutics","sponsor":"Bristol Myers Squibb","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"Bempegaldesleukin","moa":"IL-2 beta receptor","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nektar Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Nektar Therapeutics \/ Bristol Myers Squibb","highestDevelopmentStatusID":"7","companyTruncated":"Nektar Therapeutics \/ Bristol Myers Squibb"},{"orgOrder":0,"company":"Clearside Biomedical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Axitinib","moa":"VEGF 1\/2\/3","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Clearside 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III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Merck & Co \/ Pfizer Inc","highestDevelopmentStatusID":"10","companyTruncated":"Merck & Co \/ Pfizer Inc"},{"orgOrder":0,"company":"Clearside Biomedical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Axitinib","moa":"VEGF 1\/2\/3","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Clearside Biomedical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Suprachoroidal Injection","sponsorNew":"Clearside Biomedical \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Clearside Biomedical \/ Not Applicable"},{"orgOrder":0,"company":"Ocular Therapeutix","sponsor":"Not 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Ocular Therapeutix","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Ocular Therapeutix \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Ocular Therapeutix \/ Not Applicable"},{"orgOrder":0,"company":"Clearside Biomedical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Clearside Biomedical","amount2":0,"highestDevelopmentShortName":"Ph 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Clearside Biomedical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"Clearside Biomedical \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Clearside Biomedical \/ Not Applicable"},{"orgOrder":0,"company":"Ocular Therapeutix","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Small molecule","year":"2023","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Ophthalmology","graph2":"Phase I","graph3":"Ocular Therapeutix","amount2":0,"highestDevelopmentShortName":"Ph 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molecule","year":"2024","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Ocular Therapeutix","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"","sponsorNew":"Ocular Therapeutix \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Ocular Therapeutix \/ Not Applicable"},{"orgOrder":0,"company":"AiViva Biopharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Axitinib","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"AiViva Biopharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"AiViva Biopharma \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"AiViva Biopharma \/ Not 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Biomedical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Suprachoroidal Injection","sponsorNew":"Clearside Biomedical \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Clearside Biomedical \/ Inapplicable"}]

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01

ELCC
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ELCC
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Details : CLS-AX (axitinib) is a pan-tyrosine kinase inhibitor, small molecule drug candidate, which is being evaluated for the treatment of neovascular age-related macular degeneration.

Product Name : CLS-AX

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

March 06, 2025

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : CLS-AX (axitinib) is a pan-tyrosine kinase inhibitor, small molecule drug candidate, which is being evaluated for the treatment of neovascular age-related macular degeneration.

Product Name : CLS-AX

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

February 10, 2025

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : AIV001 (axitinib) is a pan-tyrosine kinase inhibitor, small molecule drug candidate, which is being evaluated for the treatment of nonmelanoma skin cancer.

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

December 09, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Oncology

Highest Development Status : IND Enabling

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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04

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.

Product Name : Axpaxli

Product Type : Small molecule

Upfront Cash : Not Applicable

October 15, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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05

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.

Product Name : CLS-AX

Product Type : Small molecule

Upfront Cash : Not Applicable

October 09, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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06

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : CLS-AX (axitinib injectable suspension) is a tyrosine kinase inhibitor (TKI), is under Phase 2b clinical trial for the treatment of wet AMD.

Product Name : CLS-AX

Product Type : Small molecule

Upfront Cash : Not Applicable

August 27, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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07

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant with axitinib, small molecule TKI with anti-angiogenic properties. It is being developed for the treatment of wet AMD.

Product Name : Axpaxli

Product Type : Small molecule

Upfront Cash : Not Applicable

August 07, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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08

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : Axpaxli (axitinib) is an investigational bioresorbable, hydrogel implant incorporating axitinib, a small molecule, multi-target, tyrosine kinase inhibitor for the treatment of WET AMD.

Product Name : Axpaxli

Product Type : Small molecule

Upfront Cash : Not Applicable

July 30, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase III

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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09

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : Axpaxli (axitinib) is a bioresorbable hydrogel implant incorporating axitinib, a multi-target tyrosine kinase inhibitor, being developed for diabetic retinopathy treatment.

Product Name : Axpaxli

Product Type : Small molecule

Upfront Cash : Not Applicable

April 18, 2024

Lead Product(s) : Axitinib

Therapeutic Area : Ophthalmology

Highest Development Status : Phase I

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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10

ELCC
Not Confirmed
ELCC
Not Confirmed

Details : JS001 (toripalimab) is an anti-PD-1 monoclonal antibody developed for its ability to block PD-1 interactions. It is approved in combination with axitinib for the treatment of renal carcinoma.

Product Name : Tuoyi

Product Type : Large molecule

Upfront Cash : Not Applicable

April 07, 2024

Lead Product(s) : Toripalimab,Axitinib

Therapeutic Area : Oncology

Highest Development Status : Approved

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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