Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Satralizumab,Azathioprine,Mycophenolate Mofetil
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Roche’s Enspryng Leads Latest CHMP Recommendations
Details : Leading those recommendations is Roche’s Enspryng (satralizumab), which received a positive opinion for the treatment of the rare autoimmune disease neuromyelitis optica spectrum disorders (NMOSD).
Brand Name : Enspryng
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 23, 2021
Lead Product(s) : Satralizumab,Azathioprine,Mycophenolate Mofetil
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study showed that avacopan was as effective as prednisone therapy in bringing patients into remission by 26 weeks, and superior to prednisone for sustained remission after 52 weeks.
Brand Name : CCX168
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 06, 2020
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Amgen Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : If approved, avacopan would be the first orally administered selective complement 5a receptor inhibitor, for the treatment of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis.
Brand Name : CCX168
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 03, 2020
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Amgen Inc
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The NDA included data from the global, Phase III ADVOCATE trial, which demonstrated statistical superiority in sustaining remission at 52 weeks in the avacopan group compared to the prednisone group.
Brand Name : CCX168
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 17, 2020
Lead Product(s) : Avacopan,Rituximab,Azathioprine
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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