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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : AZD1656, a HK-4 glucokinase activator, is now being repurposed by Conduit for for the treatment of systemic lupus erythematosus (including lupus nephritis) and ANCA-associated vasculitis.

                          Brand Name : AZD1656

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 12, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : AstraZeneca

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through the License Agreement, Conduit will analyze existing clinical data and initiate Phase II trial studies of AZD1656 for treating Lupus Nephritis and Renal Transplant.

                          Brand Name : AZD1656

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 08, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase I

                          Sponsor : Conduit Pharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          ClinConnect

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                          Pharmtech & Ingredients
                          Not Confirmed

                          ClinConnect

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                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : ClinConnect in partnership with Conduit, will seek to identify, characterize, and validate suitable cocrystal partners for AZD1656 to solve for current challenges associated with solubility, stability, and bioavailability.

                          Brand Name : AZD1656

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 11, 2023

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Conduit Pharma

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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