[{"orgOrder":0,"company":"Sarborg","sponsor":"Conduit Pharma","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Agreement","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase II","graph3":"Sarborg","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Sarborg \/ Conduit Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Sarborg \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Charles River Laboratories, Inc","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Collaboration","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Charles River Laboratories, Inc","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Charles River Laboratories, Inc"},{"orgOrder":0,"company":"ClinConnect","sponsor":"Conduit Pharma","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Partnership","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase II","graph3":"ClinConnect","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"ClinConnect \/ Conduit Pharma","highestDevelopmentStatusID":"8","companyTruncated":"ClinConnect \/ Conduit Pharma"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"AstraZeneca","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Conduit Pharma \/ AstraZeneca","highestDevelopmentStatusID":"4","companyTruncated":"Conduit Pharma \/ AstraZeneca"},{"orgOrder":0,"company":"Conduit Pharma","sponsor":"Sarborg Limited","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase II","graph3":"Conduit Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Conduit Pharma \/ Sarborg Limited","highestDevelopmentStatusID":"8","companyTruncated":"Conduit Pharma \/ Sarborg Limited"},{"orgOrder":0,"company":"AstraZeneca","sponsor":"Conduit Pharma","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"UNITED KINGDOM","productType":"Other Small Molecule","year":"2024","type":"Licensing Agreement","leadProduct":"AZD1656","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase I","graph3":"AstraZeneca","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"AstraZeneca \/ Conduit Pharma","highestDevelopmentStatusID":"6","companyTruncated":"AstraZeneca \/ Conduit Pharma"}]

Find Clinical Drug Pipeline Developments & Deals for AZD1656

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : AZD1656 is a glucokinase activator small molecule drug candidate, which is currently being evaluated for the treatment of patients with lupus nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 20, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Sarborg Limited

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Conduit will leverage Charles River’s expertise in immunology and preclinical research to help in development of AZD1656 for Lupus Nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 13, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Charles River Laboratories, Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          Sarborg

                          Country arrow
                          Interphex
                          Not Confirmed

                          Sarborg

                          Country arrow
                          Interphex
                          Not Confirmed

                          Details : Conduit and Sarborg worked closely to align AI-driven processes with Conduit’s portfolio needs, enhancing the potential of key assets, including AZD1656 is being evaluated for Lupus Nephritis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : $0.4 million

                          February 07, 2025

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase II

                          Sponsor : Conduit Pharma

                          Deal Size : $2.2 million

                          Deal Type : Agreement

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                          04

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : AZD1656, a HK-4 glucokinase activator, is now being repurposed by Conduit for for the treatment of systemic lupus erythematosus (including lupus nephritis) and ANCA-associated vasculitis.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 08, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : AstraZeneca

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Through the License Agreement, Conduit will analyze existing clinical data and initiate Phase II trial studies of AZD1656 for treating Lupus Nephritis and Renal Transplant.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          August 08, 2024

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase I

                          Sponsor : Conduit Pharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          ClinConnect

                          Country arrow
                          Interphex
                          Not Confirmed

                          ClinConnect

                          Country arrow
                          Interphex
                          Not Confirmed

                          Details : ClinConnect in partnership with Conduit, will seek to identify, characterize, and validate suitable cocrystal partners for AZD1656 to solve for current challenges associated with solubility, stability, and bioavailability.

                          Product Name : AZD1656

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 10, 2023

                          Lead Product(s) : AZD1656

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Conduit Pharma

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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