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                            01

                            Barinthus Biotherapeutics

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                            Lead Product(s) : ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Barinthus Bio Completes Enrollment in HBV And Prostate Cancer Trials

                            Details : Barinthus lead product VTP-300 (ChAdOx1-HBV) vaccine is being evaluated in mid-stage clinical trial studies in combination with Nivolumab for treating adults with chronic hepatitis B.

                            Brand Name : VTP-300

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 01, 2024

                            Lead Product(s) : ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

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                            Lead Product(s) : VTP-1000

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Barinthus Initiates Phase 1 Trial of VTP-1000 for Celiac Disease

                            Details : VTP-1000 is an investigational, injectable antigen-specific tolerance immunotherapy that utilizes Barinthus Bio’s platform. Currently, it is being evaluated for the treatment of celiac disease.

                            Brand Name : VTP-1000

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            September 24, 2024

                            Lead Product(s) : VTP-1000

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Barinthus Bio Reports Topline Data from APOLLO Trial Of VTP-200

                            Details : VTP-200 is an investigational immunotherapeutic regimen combining the ChAdOx vector and MVA vector encoding HPV antigens, evaluated for high-risk HPV infections in women.

                            Brand Name : HPV001

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            April 18, 2024

                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

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                            Lead Product(s) : VTP-500

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : CEPI

                            Deal Size : $34.8 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            New Partnership Aims to Advance Vaccine Against MERS Coronavirus

                            Details : The partnership aims to fast-track the development of a vaccine candidate known as VTP-500 for the prevention of Middle East Respiratory Syndrome, the often fatal disease caused by the MERS coronavirus.

                            Brand Name : VTP-500

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            December 21, 2023

                            Lead Product(s) : VTP-500

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : CEPI

                            Deal Size : $34.8 million

                            Deal Type : Partnership

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                            05

                            Barinthus Biotherapeutics

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                            Lead Product(s) : ChAdOx1-PCAQ,MVA-PCAQ

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech Doses First Patient in PCA001, a Prostate Cancer Phase 1/2 Clinical Trial of VTP-850 Immunotherapeut...

                            Details : VTP-850 (ChAdOx1-PCAQ) is a next-generation prostate cancer immunotherapeutic candidate which utilizes Vaccitech’s sequential dosing approach of two proprietary nonreplicating viral vectors, ChAdOx and MVA.

                            Brand Name : VTP-850

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            June 12, 2023

                            Lead Product(s) : ChAdOx1-PCAQ,MVA-PCAQ

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Barinthus Biotherapeutics

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                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech Announces Positive Topline Final Data for HBV002 Study in People with Chronic Hepatitis B

                            Details : VTP-300 (MVA-HBV) is a first antigen-specific immunotherapy consists of an initial dose using the ChAdOx platform and a secondary dose using MVA encoding multiple hepatitis B antigens, including full-length surface, modified polymerase and core antigens.

                            Brand Name : VTP-300

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 28, 2023

                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech’s VTP-200 Ph 1b/2 Study Demonstrates Favorable Tolerability and Immunogenicity Profile at Interim ...

                            Details : VTP-200 is an investigational heterologous prime boost immunotherapy consisting of an initial dose using the ChAdOx vector and a second dose using MVA, both encoding the same HPV antigens, to elicit an immune response to HPV.

                            Brand Name : VTP-200

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 20, 2023

                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

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                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech Provides Update on Ongoing VTP-300 Phase 1b/2a Trial Showing Sustained Reductions of HBsAg in Patien...

                            Details : VTP-300 administered as a monotherapy or in combination with a single administration of low-dose nivolumab at the time of the booster dose was administered with no treatment-related serious adverse events and infrequent transient transaminitis.

                            Brand Name : VTP-300

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 07, 2022

                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

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                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech Announces Late-Breaker Abstract Accepted for Presentation at AASLD - The Liver Meeting® Providing U...

                            Details : VTP-300 (also named as MVA-HBV), is a novel immunotherapy, dosed in a prime-boost regimen, whereby the immune system is primed with an adenovirus (ChAdOx) and boosted with a pox virus (MVA).

                            Brand Name : VTP-300

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 02, 2022

                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Barinthus Biotherapeutics

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                            Barinthus Biotherapeutics

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                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Vaccitech's VTP-300 Induced Sustained Reductions of Surface Antigen in Patients With Chronic Hepatitis B Both ...

                            Details : Meaningful, durable reductions of Hepatitis B surface antigen (HBsAg) were seen in some patients who received VTP-300 (MVA-HBV) as either a monotherapy or in combination with a single low dose of nivolumab at the booster dose.

                            Brand Name : VTP-300

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            June 22, 2022

                            Lead Product(s) : MVA-HBV,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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