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    [{"orgOrder":0,"company":"Barinthus Biotherapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Vaccine","year":"2024","type":"Inapplicable","leadProduct":"VTP-1000","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Phase I","graph3":"Barinthus Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Barinthus Biotherapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Barinthus Biotherapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Barinthus Biotherapeutics","sponsor":"UK Research And Innovation","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Vaccine","year":"2020","type":"Funding","leadProduct":"COVID-19 Vaccine","moa":"SARS-CoV-2 S","graph1":"Infections and Infectious 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KINGDOM","productType":"Vaccine","year":"2023","type":"Inapplicable","leadProduct":"ChAdOx1-PCAQ","moa":"||Undisclosed","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Barinthus Biotherapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Barinthus Biotherapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Barinthus Biotherapeutics \/ Inapplicable"}]

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                            01

                            Barinthus Biotherapeutics

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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-300,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Barinthus Reports Phase 2b Hepatitis B Trial Achieves Cure, HBsAb Seroconversion

                            Details : Barinthus lead product VTP-300 (ChAdOx1-HBV) vaccine is being evaluated in mid-stage clinical trial studies in combination with Nivolumab for treating adults with chronic hepatitis B.

                            Product Name : VTP-300

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            November 15, 2024

                            Lead Product(s) : VTP-300,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : VTP-1000

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Barinthus Initiates Phase 1 Trial of VTP-1000 for Celiac Disease

                            Details : VTP-1000 is an investigational, injectable antigen-specific tolerance immunotherapy that utilizes Barinthus Bio’s platform. Currently, it is being evaluated for the treatment of celiac disease.

                            Product Name : VTP-1000

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            September 24, 2024

                            Lead Product(s) : VTP-1000

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Barinthus Bio Reports Topline Data from APOLLO Trial Of VTP-200

                            Details : VTP-200 is an investigational immunotherapeutic regimen combining the ChAdOx vector and MVA vector encoding HPV antigens, evaluated for high-risk HPV infections in women.

                            Product Name : VTP-200

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            April 18, 2024

                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-300,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Barinthus Bio Completes Enrollment in HBV And Prostate Cancer Trials

                            Details : Barinthus lead product VTP-300 (ChAdOx1-HBV) vaccine is being evaluated in mid-stage clinical trial studies in combination with Nivolumab for treating adults with chronic hepatitis B.

                            Product Name : VTP-300

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            January 10, 2024

                            Lead Product(s) : VTP-300,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-500

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : CEPI

                            Deal Size : $34.8 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            New Partnership Aims to Advance Vaccine Against MERS Coronavirus

                            Details : The partnership aims to fast-track the development of a vaccine candidate known as VTP-500 for the prevention of Middle East Respiratory Syndrome, the often fatal disease caused by the MERS coronavirus.

                            Product Name : VTP-500

                            Product Type : Vaccine

                            Upfront Cash : Undisclosed

                            December 21, 2023

                            Lead Product(s) : VTP-500

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : CEPI

                            Deal Size : $34.8 million

                            Deal Type : Partnership

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                            06

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : ChAdOx1-PCAQ,MVA-PCAQ

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaccitech Doses First Patient in PCA001, a Prostate Cancer Phase 1/2 Clinical Trial of VTP-850 Immunotherapeut...

                            Details : VTP-850 (ChAdOx1-PCAQ) is a next-generation prostate cancer immunotherapeutic candidate which utilizes Vaccitech’s sequential dosing approach of two proprietary nonreplicating viral vectors, ChAdOx and MVA.

                            Product Name : VTP-850

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            December 06, 2023

                            Lead Product(s) : ChAdOx1-PCAQ,MVA-PCAQ

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Barinthus Biotherapeutics

                            United Kingdom arrow
                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaccitech Announces Positive Topline Final Data for HBV002 Study in People with Chronic Hepatitis B

                            Details : VTP-300 (MVA-HBV) is a first antigen-specific immunotherapy consists of an initial dose using the ChAdOx platform and a secondary dose using MVA encoding multiple hepatitis B antigens, including full-length surface, modified polymerase and core antigens.

                            Product Name : VTP-300

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            March 28, 2023

                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaccitech’s VTP-200 Ph 1b/2 Study Demonstrates Favorable Tolerability and Immunogenicity Profile at Interim ...

                            Details : VTP-200 is an investigational heterologous prime boost immunotherapy consisting of an initial dose using the ChAdOx vector and a second dose using MVA, both encoding the same HPV antigens, to elicit an immune response to HPV.

                            Product Name : VTP-200

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            March 20, 2023

                            Lead Product(s) : VTP-200

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Barinthus Biotherapeutics

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                            AACR Annual meeting
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                            Barinthus Biotherapeutics

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                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaccitech Provides Update on Ongoing VTP-300 Phase 1b/2a Trial Showing Sustained Reductions of HBsAg in Patien...

                            Details : VTP-300 administered as a monotherapy or in combination with a single administration of low-dose nivolumab at the time of the booster dose was administered with no treatment-related serious adverse events and infrequent transient transaminitis.

                            Product Name : VTP-300

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            July 11, 2022

                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Barinthus Biotherapeutics

                            United Kingdom arrow
                            AACR Annual meeting
                            Not Confirmed

                            Barinthus Biotherapeutics

                            United Kingdom arrow
                            AACR Annual meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Vaccitech's VTP-300 Induced Sustained Reductions of Surface Antigen in Patients With Chronic Hepatitis B Both ...

                            Details : Meaningful, durable reductions of Hepatitis B surface antigen (HBsAg) were seen in some patients who received VTP-300 (MVA-HBV) as either a monotherapy or in combination with a single low dose of nivolumab at the booster dose.

                            Product Name : VTP-300

                            Product Type : Vaccine

                            Upfront Cash : Inapplicable

                            June 22, 2022

                            Lead Product(s) : VTP-300,ChAdOx1-HBV,Nivolumab

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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