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Find Clinical Drug Pipeline Developments & Deals by Basilea Pharmaceutica

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Cresemba (isavuconazonium sulfate) is the prodrug of isavuconazole which is an azole antifungal indicated for the treatment of invasive aspergillosis and invasive mucormycosis.

                          Brand Name : Cresemba

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 10, 2024

                          Lead Product(s) : Isavuconazonium Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Pfizer Inc

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : PF-07842805 (fosmanogepix), a potential first-in-class, clinical-stage broad-spectrum antifungal treatment candidate for Candidemia, including Candida auris, and invasive mold infections.

                          Brand Name : PF-07842805

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 23, 2024

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The funding aims to support the development of Basilea’s clinical stage first-in-class antifungal, APX-001 (fosmanogepix), which is being investigated for the treatment of invasive candidiasis.

                          Brand Name : APX-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 19, 2024

                          Lead Product(s) : Fosmanogepix

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : BARDA

                          Deal Size : $29.0 million

                          Deal Type : Funding

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : FDA approves expanded use of Cresemba® (isavuconazonium sulfate), an ergosterol inhibitor, in pediatric patients 1 year of age and older with invasive aspergillosis and invasive mucormycosis.

                          Brand Name : Cresemba

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 27, 2024

                          Lead Product(s) : Isavuconazonium Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the terms of the agreement, Basilea sells and transfers all rights to BAL101553 (lisavanbulin) to the Glioblastoma Foundation. It is currently being evaluated for the treatment of neoplasms.

                          Brand Name : BAL101553

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 20, 2024

                          Lead Product(s) : Lisavanbulin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Glioblastoma Foundation Inc

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Funding will support clinical development of first-in-class antibiotics targeting severe infections, particularly those caused by E. coli and K. pneumoniae.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 09, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : CARB-X

                          Deal Size : $0.9 million

                          Deal Type : Funding

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Zevtera is approved for adult patients with S. aureus bloodstream infections, acute bacterial skin and skin structure infections & community-acquired bacterial pneumonia in both adults and pediatrics.

                          Brand Name : Zevtera

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 04, 2024

                          Lead Product(s) : Ceftobiprole Medocaril

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Knight will commercialize Cresemba (isavuconazole sulfate) in Latin America, an azole antifungal for treating adult patients with invasive aspergillosis, licensed for regional distribution.

                          Brand Name : Cresemba

                          Molecule Type : Small molecule

                          Upfront Cash : $11.2 million

                          January 19, 2024

                          Lead Product(s) : Isavuconazonium Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Knight Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through the acquisition, Basilea gains a preclinical program of antibiotics from a novel class, targeting Gram-negative bacteria, including multidrug-resistant strains.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 15, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Spexis

                          Deal Size : $2.3 million

                          Deal Type : Acquisition

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Pfizer has the right to manufacture Cresemba, an intravenous, oral azole antifungal, and exclusively commercialize the drug in Europe, the Asia Pacific and China regions. Isavuconazonium sulfate has been approved in 73 countries for invasive aspergillosi...

                          Brand Name : Cresemba

                          Molecule Type : Small molecule

                          Upfront Cash : $72.3 million

                          November 20, 2023

                          Lead Product(s) : Isavuconazonium Sulfate

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Pfizer Inc

                          Deal Size : $1,095.4 million

                          Deal Type : Licensing Agreement

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