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Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"CHIKV VLP","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Bavarian Nordic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bavarian Nordic \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Bavarian Nordic \/ Not Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"Live Nonreplicating Smallpox and Monkeypox Vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Bavarian Nordic","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bavarian Nordic \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Bavarian Nordic \/ Not Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"Live Nonreplicating Smallpox and Monkeypox Vaccine","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Bavarian Nordic","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bavarian Nordic \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Bavarian Nordic \/ Not Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"European Union","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Funding","leadProduct":"Modified Vaccinia Ankara","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Bavarian Nordic","amount2":0.070000000000000007,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.070000000000000007,"dosageForm":"Injection","sponsorNew":"Bavarian Nordic \/ European Union","highestDevelopmentStatusID":"12","companyTruncated":"Bavarian Nordic \/ European Union"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"CHIKV VLP","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Bavarian Nordic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Injection","sponsorNew":"Bavarian Nordic \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Bavarian Nordic \/ Not Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"CEPI","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Partnership","leadProduct":"Live Modified Vaccinia Virus Ankara","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase I","graph3":"Bavarian Nordic","amount2":0.01,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.01,"dosageForm":"","sponsorNew":"Bavarian Nordic \/ CEPI","highestDevelopmentStatusID":"6","companyTruncated":"Bavarian Nordic \/ CEPI"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"CHIKV VLP","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase III","graph3":"Bavarian Nordic","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Bavarian Nordic \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Bavarian Nordic \/ Not Applicable"},{"orgOrder":0,"company":"Bavarian Nordic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"DENMARK","productType":"Vaccine","year":"2024","type":"Not Applicable","leadProduct":"Modified Vaccinia Ankara-Bavarian Nordic","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Phase 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Find Clinical Drug Pipeline Developments & Deals by Bavarian Nordic

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The funding will be used to manufacture additional bulk product and final freeze-dried doses of Jynneos indicated for the prevention of both smallpox and mpox infection.

                          Brand Name : Jynneos

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 24, 2024

                          Lead Product(s) : Smallpox and Monkeypox Vaccine, Live, Nonreplicating

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : BARDA

                          Deal Size : $63.0 million

                          Deal Type : Funding

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imvanex (modified vaccinia ankara) is a non-replicating approved vaccine, which is being evaluated for the treatment of small pox and mpox in adolescents 12 to 17 years of age.

                          Brand Name : Imvanex

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          September 19, 2024

                          Lead Product(s) : Modified Vaccinia Ankara

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the terms of the agreement, Nordic will supply Imvanex (Modified Vaccinia Ankara), a non-replicating vaccine approved in Africa. It is indicated for the treatment of smallpox and mpox.

                          Brand Name : Imvanex

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          September 18, 2024

                          Lead Product(s) : Modified Vaccinia Ankara

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Gavi

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Jynneos (live nonreplicating smallpox and monkeypox vaccine) is approved for prevention of smallpox and monkeypox disease in adults 18 years of age and older.

                          Brand Name : Jynneos

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          August 27, 2024

                          Lead Product(s) : Modified Vaccinia Ankara-Bavarian Nordic

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imvanex (modified vaccinia ankara) is a non-replicating approved vaccine, which is being evaluated for the treatment of small pox and mpox in adolescents 12 to 17 years of age.

                          Brand Name : Imvanex

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          August 16, 2024

                          Lead Product(s) : Modified Vaccinia Ankara

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : CHIKV VLP is a vaccine candidate which is being investigated for immunization against chikungunya virus infection in individuals 12 years of age and older.

                          Brand Name : PXVX0317

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          August 13, 2024

                          Lead Product(s) : CHIKV VLP

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The funding aims to advance the manufacturing of additional bulk products for Jynneos (live nonreplicating smallpox and monkeypox vaccine) for treating smallpox/mpox.

                          Brand Name : Jynneos

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          August 08, 2024

                          Lead Product(s) : Live Nonreplicating Smallpox and Monkeypox Vaccine

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : BARDA

                          Deal Size : $156.8 million

                          Deal Type : Funding

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Imvanex (modified vaccinia ankara) is a non-replicating approved vaccine, given subcutaneously for the treatment of small pox and mpox. It is approved by the FDA, EC, Health Canada, MHRA & Swissmedic.

                          Brand Name : Imvanex

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          July 26, 2024

                          Lead Product(s) : Modified Vaccinia Ankara

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : CHIKV VLP is a vaccine candidate which is being investigated for immunization against chikungunya virus infection in individuals 12 years of age and older.

                          Brand Name : PXVX0317

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          June 17, 2024

                          Lead Product(s) : CHIKV VLP

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Company has filed sBLA seeking approval for its new freeze-dried formulation of JYNNEOS® for prevention of smallpox and mpox disease in adults 18 years of age and older.

                          Brand Name : Jynneos

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          May 31, 2024

                          Lead Product(s) : Modified Vaccinia Ankara-Bavarian Nordic

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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