Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Nogapendekin Alfa Inbakicept,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
ImmunityBio Receives FDA Approval for ANKTIVA® in Bladder Cancer Treatment
Details : Anktiva (nogapendekin alfa inbakicept-pmln) is an IL-15 receptor agonist, evaluated with Bacillus Calmette-Guérin (BCG) for BCG-unresponsive non-muscle invasive bladder cancer treatment.
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 22, 2024
Lead Product(s) : Nogapendekin Alfa Inbakicept,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Oberland Capital
Deal Size : $320.0 million
Deal Type : Financing
ImmunityBio Secures $320 Million Investment, Totaling $850 Million in 2023
Details : Proceeds will also support N-803 (Anktiva), an interleukin-15 superagonist fusion protein, currently in clinical trials for solid tumors including BCG-unresponsive non-muscle invasive bladder cancer.
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 02, 2024
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Oberland Capital
Deal Size : $320.0 million
Deal Type : Financing
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Accepts ImmunityBio’s BLA Resubmission as Complete and Sets New PDUFA Date
Details : Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease...
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 26, 2023
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease...
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 23, 2023
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Nant Capital
Deal Size : Undisclosed
Deal Type : Financing
Details : The financing will fund company's ongoing business operations and pre-commercialization efforts as it continues to drive toward a potential regulatory approval of Anktiva (N-803), a novel IL-15 superagonist, plus BCG for BCG-unresponsive non-muscle invas...
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 11, 2023
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Nant Capital
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Anktiva™ (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex and has received breakthrough therapy and fast track designations from the U.S. FDA for BCG-unresponsive CIS non-muscle invasive bladder cancer.
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 16, 2023
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BCG Vaccine
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Serum Institute Seeks Nod For Adult TB Vaccine
Details : The vaccine, TUBERVAC-rBCG can be administered to children and adults both. Once DCGI approves Serum Institute's TB vaccine, the National Technical Advisory Group on Immunisation (NTAGI) will decide on its introduction.
Brand Name : TUBERVAC-rBCG
Molecule Type : Vaccine
Upfront Cash : Not Applicable
December 13, 2022
Lead Product(s) : BCG Vaccine
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Positive QUILT 3.032 trial for Anktiva (N-803) results in 71% of BCG-unresponsive NMIBC patients who had failed on previous therapies showed complete response with duration of 26.6 months; cystectomy avoidance rate of 91% and 100% bladder cancer overall ...
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 28, 2022
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Data demonstrate for BCG-unresponsive bladder cancer patients who were treated with BCG plus N-803 (Anktiva) and the doubling of historic overall survival rates in patients with advanced pancreatic cancer who were treated with the Nant Cancer Vaccine.
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 06, 2022
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Anktiva™ (N-803) is an IL-15RαFc Superagonist, a proprietary therapeutic cytokine designed to induce expansion of native NK and CD8+ T-cells without concurrent stimulation of T-regulatory cells
Brand Name : Anktiva
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 23, 2022
Lead Product(s) : N-803,BCG Vaccine
Therapeutic Area : Oncology
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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