Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Black Diamond Reshuffles Execs, Drops Phase 1 Lung Cancer Drug
Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
October 07, 2024
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Black Diamond Shows Phase 2 Data of BDTX-1535 with Strong Activity in EGFRm NSCLC
Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
September 23, 2024
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation in a Phase 1 clinical trial for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
December 13, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535, is a EGFR inhibitor (TKI), is under investigation for the treatment of NSCLC harboring intrinsic driver and/or acquired resistance (post-osimertinib) EGFR mutations and glioblastoma multiforme (GBM) with multiple EGFR alterations.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
September 11, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Black Diamond Therapeutics Announces Pricing of Public Offering of Common Stock
Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both EGFR mutant-positive NSCLC and in glioblastoma mu...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
June 29, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Black Diamond Therapeutics Announces Proposed Public Offering of Common Stock
Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both EGFR mutant-positive NSCLC and in glioblastoma mu...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
June 28, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NS...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
June 27, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NS...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
December 12, 2022
Details : BDTX-1535 is an irreversible MasterKey inhibitor of multiple EGFR alterations that utilize similar activated oncogenic EGFR conformations to drive tumor cell growth in GBM and NSCLC.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
October 26, 2022
Details : BDTX-1535 is designed as an irreversible, mutant selective, brain-penetrant MasterKey inhibitor of oncogenic mutations of epidermal growth factor receptor expressed in glioblastoma multiforme and intrinsic and acquired resistance EGFR mutations in non-sm...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2022