Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation in a Phase 1 clinical trial for the treatment of patients with non-small cell lung cancer (NSCLC) or recurr...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
December 13, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535, is a EGFR inhibitor (TKI), is under investigation for the treatment of NSCLC harboring intrinsic driver and/or acquired resistance (post-osimertinib) EGFR mutations and glioblastoma multiforme ...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
September 11, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Black Diamond Therapeutics Announces Pricing of Public Offering of Common Stock
Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
June 29, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Black Diamond Therapeutics Announces Proposed Public Offering of Common Stock
Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
June 28, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Piper Sandler
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistanc...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
June 27, 2023
Lead Product(s) : BDTX-1535,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistanc...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Undisclosed
December 12, 2022
Details : BDTX-1535 is an irreversible MasterKey inhibitor of multiple EGFR alterations that utilize similar activated oncogenic EGFR conformations to drive tumor cell growth in GBM and NSCLC.
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
October 26, 2022
Details : BDTX-1535 is designed as an irreversible, mutant selective, brain-penetrant MasterKey inhibitor of oncogenic mutations of epidermal growth factor receptor expressed in glioblastoma multiforme and intrinsi...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2022
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535 is designed as potent brain-penetrant inhibitor of a spectrum of EGFR mutations expressed in glioblastoma multiforme and NSCLC. BDTX-1535 showed dose-dependent tumor growth inhibition and achiev...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
October 08, 2021
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BDTX-1535, a CNS penetrant MasterKey inhibitor of common, uncommon and resistant EGFR mutations, demonstrates in vivo efficacy and has potential to treat osimertinib-resistant NSCLC with or without brain ...
Product Name : BDTX-1535
Product Type : Small molecule
Upfront Cash : Not Applicable
September 30, 2021
Lead Product(s) : BDTX-1535
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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