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Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Black Diamond Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Black Diamond Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Black Diamond Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"BDTX-1535","moa":"EGFR","graph1":"Oncology","graph2":"Phase I","graph3":"Black Diamond Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Black Diamond Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Black Diamond Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Black Diamond Therapeutics","sponsor":"Not 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Find Clinical Drug Pipeline Developments & Deals for BDTX-1535

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                          01

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 07, 2024

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 23, 2024

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535, a fourth-generation, brain-penetrant, covalent EGFR inhibitor, is under investigation in a Phase 1 clinical trial for the treatment of patients with non-small cell lung cancer (NSCLC) or recurrent glioblastoma GBM.

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 13, 2023

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535, is a EGFR inhibitor (TKI), is under investigation for the treatment of NSCLC harboring intrinsic driver and/or acquired resistance (post-osimertinib) EGFR mutations and glioblastoma multiforme (GBM) with multiple EGFR alterations.

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 11, 2023

                          Lead Product(s) : BDTX-1535,Temozolomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both EGFR mutant-positive NSCLC and in glioblastoma mu...

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 29, 2023

                          Lead Product(s) : BDTX-1535,Temozolomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Piper Sandler

                          Deal Size : $75.0 million

                          Deal Type : Public Offering

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                          06

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : The net proceeds will be used for the advancement of the Company’s clinical development pipeline, including potential accelerated approval activities for BDTX-1535, targeting MasterKey mutations in both EGFR mutant-positive NSCLC and in glioblastoma mu...

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 28, 2023

                          Lead Product(s) : BDTX-1535,Temozolomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Piper Sandler

                          Deal Size : $75.0 million

                          Deal Type : Public Offering

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                          07

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NS...

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 27, 2023

                          Lead Product(s) : BDTX-1535,Temozolomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535 is designed to be a potent, selective, brain penetrant and irreversible MasterKey inhibitor of EGFR mutations that expressed in glioblastoma multiforme (GBM) and intrinsic and acquired resistance EGFR mutations in non-small cell lung cancer (NS...

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 12, 2022

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Versant Ventures

                          Deal Size : Undisclosed

                          Deal Type : Series A Financing

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                          09

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535 is an irreversible MasterKey inhibitor of multiple EGFR alterations that utilize similar activated oncogenic EGFR conformations to drive tumor cell growth in GBM and NSCLC.

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 26, 2022

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          The Generic Rx Session
                          Not Confirmed
                          The Generic Rx Session
                          Not Confirmed

                          Details : BDTX-1535 is designed as an irreversible, mutant selective, brain-penetrant MasterKey inhibitor of oncogenic mutations of epidermal growth factor receptor expressed in glioblastoma multiforme and intrinsic and acquired resistance EGFR mutations in non-sm...

                          Product Name : BDTX-1535

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 18, 2022

                          Lead Product(s) : BDTX-1535

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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