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    [{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Syncona Limited","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2023","type":"Financing","leadProduct":"Recombinant Adeno-associated Virus Vector","moa":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III","graph3":"Beacon Therapeutics","amount2":0.12,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Genetic Disease","amount2New":0.12,"dosageForm":"Injectable\/Injection","sponsorNew":"Beacon Therapeutics \/ Syncona Limited","highestDevelopmentStatusID":"9","companyTruncated":"Beacon Therapeutics \/ Syncona Limited"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Laruparetigene Zovaparvovec","moa":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III","graph3":"Beacon Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"9","companyTruncated":"Beacon Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"TCGX","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Series B Financing","leadProduct":"Laruparetigene Zovaparvovec","moa":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III","graph3":"Beacon Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II\/III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ TCGX","highestDevelopmentStatusID":"9","companyTruncated":"Beacon Therapeutics \/ TCGX"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"TCGX","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Series B Financing","leadProduct":"Laruparetigene Zovaparvovec","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Beacon Therapeutics","amount2":0.17000000000000001,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ TCGX","highestDevelopmentStatusID":"14","companyTruncated":"Beacon Therapeutics \/ TCGX"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Abeona Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Agreement","leadProduct":"AAV204","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Beacon Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ Beacon Therapeutics","highestDevelopmentStatusID":"14","companyTruncated":"Beacon Therapeutics \/ Beacon Therapeutics"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Laruparetigene Zovaparvovec","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Beacon Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"14","companyTruncated":"Beacon Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Laruparetigene Zovaparvovec","moa":"","graph1":null,"graph2":null,"graph3":"Beacon Therapeutics","amount2":0,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"amount2New":0,"dosageForm":"","sponsorNew":"Beacon Therapeutics \/ Not Applicable","highestDevelopmentStatusID":null,"companyTruncated":"Beacon Therapeutics \/ Not Applicable"}]

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                            01

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Beacon Shows Positive 24-Month Data from AGTC-501 Phase 2 in XLRP

                            Details : AGTC-501 (laruparetigene zovaparvovec) is an XLRP GTPase regulator cell & gene therapy candidate, which is being evauated for the treatment of patients suffering from X-linked retinitis Pigmentosa.

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            October 15, 2024

                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Beacon Presents 36-Month Results from Phase I/2 HORIZON Trial of AGTC-501

                            Details : AGTC-501 (laruparetigene zovaparvovec) is an XLRP GTPase regulator cell & gene therapy candidate, which is being evauated for the treatment of patients suffering from X-linked retinitis Pigmentosa.

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 19, 2024

                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : AAV204

                            Therapeutic Area : Ophthalmology

                            Study Phase : Preclinical

                            Recipient : Abeona Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Abeona and Beacon Sign Non-Exclusive Deal for AAV204 Capsid for Ophthalmology

                            Details : Under the terms of the agreement, Beacon will be responsible for the development and commercialization of AAV204 capsid for potential use for the treatment of retinal diseases.

                            Brand Name : AAV204

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 11, 2024

                            Lead Product(s) : AAV204

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Preclinical

                            Recipient : Abeona Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II

                            Sponsor : TCGX

                            Deal Size : Undisclosed

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Beacon attracts $170M series B to push eye disease gene therapy through late-stage trial

                            Details : The funds will support the continued clinical development of Beacon's lead asset, AGTC-501 for the treatment of patients suffering from X-linked retinitis Pigmentosa.

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 03, 2024

                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II

                            Sponsor : TCGX

                            Deal Size : Undisclosed

                            Deal Type : Series B Financing

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                            05

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II/ Phase III

                            Sponsor : TCGX

                            Deal Size : $170.0 million

                            Deal Type : Series B Financing

                            DEALS_DEV arrow-down

                            Beacon attracts $170M series B to push eye disease gene therapy through late-stage trial

                            Details : The financing aims to advance the clinical development of Beacon's lead product AGTC-501 (laruparetigene zovaparvovec), which is being evaluated in the treatment of X-Linked Retinitis Pigmentosa.

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 03, 2024

                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : TCGX

                            Deal Size : $170.0 million

                            Deal Type : Series B Financing

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                            06

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Beacon Therapeutics treats first patient with AGTC-501 in pivotal VISTA trial

                            Details : AGTC-501 (laruparetigene zovaparvovec) is an XLRP GTPase regulator cell & gene therapy candidate, which is being evauated for the treatment of patients suffering from X-linked retinitis Pigmentosa.

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 17, 2024

                            Lead Product(s) : Laruparetigene Zovaparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Beacon Therapeutics

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                            Beacon Therapeutics

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                            Lead Product(s) : Recombinant Adeno-associated Virus Vector

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase II/ Phase III

                            Sponsor : Syncona Limited

                            Deal Size : $120.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Beacon Therapeutics Launches with £96 Million ($120 million) to Develop a New Generation of Gene Therapies fo...

                            Details : The financing will fund Beacon's lead asset, AGTC-501, a gene therapy program in Phase II trials for the treatment of X-linked retinitis pigmentosa. AGTC-501 expresses the full length RPGR protein, thereby addressing the full complement of photoreceptor ...

                            Brand Name : AGTC-501

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            June 12, 2023

                            Lead Product(s) : Recombinant Adeno-associated Virus Vector

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Syncona Limited

                            Deal Size : $120.0 million

                            Deal Type : Financing

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