Renejix CDMO Partner for Small Molecule Oral Dosage Forms Renejix CDMO Partner for Small Molecule Oral Dosage Forms

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[{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Syncona Limited","pharmaFlowCategory":"D","amount":"$120.0 million","upfrontCash":"Undisclosed","newsHeadline":"Beacon Therapeutics Launches with \u00a396 Million ($120 million) to Develop a New Generation of Gene Therapies for Retinal Diseases Resulting in Blindness","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II\/ Phase III","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"June 2023","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Beacon Therapeutics treats first patient with AGTC-501 in pivotal VISTA trial","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II\/ Phase III","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"June 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"TCGX","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Beacon attracts $170M series B to push eye disease gene therapy through late-stage trial","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"July 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"TCGX","pharmaFlowCategory":"D","amount":"$170.0 million","upfrontCash":"Undisclosed","newsHeadline":"Beacon attracts $170M series B to push eye disease gene therapy through late-stage trial","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Phase II\/ Phase III","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"July 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Phase II\/ Phase III"},{"orgOrder":0,"company":"Beacon Therapeutics","sponsor":"Abeona Therapeutics","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Abeona and Beacon Sign Non-Exclusive Deal for AAV204 Capsid for Ophthalmology","therapeuticArea":"Ophthalmology","highestDevelopmentStatus":"Preclinical","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"July 2024","url1":"","url2":"","graph1":"Ophthalmology","graph2":"Preclinical"}]

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            Details:

            Under the terms of the agreement, Beacon will be responsible for the development and commercialization of AAV204 capsid for potential use for the treatment of retinal diseases.

            Lead Product(s): AAV204

            Therapeutic Area: Ophthalmology Product Name: AAV204

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Recipient: Abeona Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Agreement July 11, 2024

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            The funds will support the continued clinical development of Beacon's lead asset, AGTC-501 for the treatment of patients suffering from X-linked retinitis Pigmentosa.

            Lead Product(s): Laruparetigene Zovaparvovec

            Therapeutic Area: Genetic Disease Product Name: AGTC-501

            Highest Development Status: Phase II Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: TCGX

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Series B Financing July 03, 2024

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            The financing aims to advance the clinical development of Beacon's lead product AGTC-501 (laruparetigene zovaparvovec), which is being evaluated in the treatment of X-Linked Retinitis Pigmentosa.

            Lead Product(s): Laruparetigene Zovaparvovec

            Therapeutic Area: Genetic Disease Product Name: AGTC-501

            Highest Development Status: Phase II/ Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: TCGX

            Deal Size: $170.0 million Upfront Cash: Undisclosed

            Deal Type: Series B Financing July 03, 2024

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            AGTC-501 (laruparetigene zovaparvovec) is an XLRP GTPase regulator cell & gene therapy candidate, which is being evauated for the treatment of patients suffering from X-linked retinitis Pigmentosa.

            Lead Product(s): Laruparetigene Zovaparvovec

            Therapeutic Area: Genetic Disease Product Name: AGTC-501

            Highest Development Status: Phase II/ Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 17, 2024

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            The financing will fund Beacon's lead asset, AGTC-501, a gene therapy program in Phase II trials for the treatment of X-linked retinitis pigmentosa. AGTC-501 expresses the full length RPGR protein, thereby addressing the full complement of photoreceptor damage caused by XLRP.

            Lead Product(s): Recombinant Adeno-associated Virus Vector

            Therapeutic Area: Genetic Disease Product Name: AGTC-501

            Highest Development Status: Phase II/ Phase III Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Syncona Limited

            Deal Size: $120.0 million Upfront Cash: Undisclosed

            Deal Type: Financing June 12, 2023

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