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BeiGene"},{"orgOrder":0,"company":"BeiGene","sponsor":"ImmunityBio","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Collaboration","leadProduct":"Tislelizumab","moa":"||PD-1","graph1":"Oncology","graph2":"Phase III","graph3":"BeiGene","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BeiGene \/ BeiGene","highestDevelopmentStatusID":"10","companyTruncated":"BeiGene \/ BeiGene"},{"orgOrder":0,"company":"BeiGene","sponsor":"Zymeworks","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CANADA","productType":"Antibody-drug Conjugate","year":"2022","type":"Inapplicable","leadProduct":"Zanidatamab Zovodotin","moa":"HER2","graph1":"Oncology","graph2":"Phase I","graph3":"BeiGene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BeiGene \/ BeiGene","highestDevelopmentStatusID":"6","companyTruncated":"BeiGene \/ BeiGene"},{"orgOrder":0,"company":"BeiGene","sponsor":"Duality Biologics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody-drug Conjugate","year":"2025","type":"Licensing Agreement","leadProduct":"BG-C9074","moa":"||B7-H4","graph1":"Oncology","graph2":"Phase I","graph3":"BeiGene","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BeiGene \/ BeiGene","highestDevelopmentStatusID":"6","companyTruncated":"BeiGene \/ BeiGene"}]

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                            01

                            BeiGene

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                            Lead Product(s) : Tislelizumab,Nogapendekin Alfa Inbakicept,Docetaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            ImmunityBio, BeiGene Collaborate on Phase 3 ANKTIVA, PD-1 Trial in NSCLC

                            Details : Under the agreement, combining BeiGene's Tevimbra (tislelizumab), a PD-1 checkpoint inhibitor, and ImmunityBio's Anktiva, to conduct a confirmatory randomized Phase 3 clinical trial for S-IV NSCLC.

                            Product Name : Tevimbra

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            January 29, 2025

                            Lead Product(s) : Tislelizumab,Nogapendekin Alfa Inbakicept,Docetaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            BeiGene

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                            PharmScience R&D
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                            BeiGene

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                            Lead Product(s) : THIO-102,Tislelizumab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : MAIA Biotechnology

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            MAIA, BeiGene Collaborate for Phase 2 Cancer Trials Clinical Supply

                            Details : Under the terms of the agreement, MAIA will sponsor and fund the planned clinical trials of THIO-102 and BeiGene will provide Tislelizumab for hepatocellular carcinoma, SCLC, and CRC.

                            Product Name : THIO-102

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 07, 2025

                            Lead Product(s) : THIO-102,Tislelizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : MAIA Biotechnology

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            03

                            BeiGene

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                            Lead Product(s) : BG-C9074,Tislelizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Duality Biologics

                            Deal Size : $1,300.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Nona Biosciences Updates on DualityBio's ADC Collaboration with BeiGene

                            Details : BeiGene has exercised its exclusive option to acquire global development, manufacturing, and commercialization rights for an ADC, BG-C9074 (DB-1312) from DualityBio.

                            Product Name : DB-1312

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Undisclosed

                            January 03, 2025

                            Lead Product(s) : BG-C9074,Tislelizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Duality Biologics

                            Deal Size : $1,300.0 million

                            Deal Type : Licensing Agreement

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                            04

                            BeiGene

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                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BeiGene’s Tevimbra Approved in US for First-Line Gastric Cancer Treatment

                            Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                            Product Name : Undisclosed

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 31, 2024

                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            BeiGene

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                            PharmScience R&D
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                            BeiGene

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                            Lead Product(s) : DB-1312

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Duality Biologics

                            Deal Size : $1,300.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Duality Biologics Announces B7H4 ADC Milestone Achievement and License Exercise by BeiGene

                            Details : Under the agreement, BeiGene will acquire an exclusive option for a global clinical and commercial license to DB-1312, an investigational antibody-drug conjugate therapy for solid tumors.

                            Product Name : DB-1312

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            December 30, 2024

                            Lead Product(s) : DB-1312

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Duality Biologics

                            Deal Size : $1,300.0 million

                            Deal Type : Agreement

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                            06

                            BeiGene

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                            Lead Product(s) : SYH2039

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : CSPC Zhongqi Pharmaceutical Technology

                            Deal Size : $150.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            BeiGene Announces Global Licensing Agreement for MAT2A Inhibitor

                            Details : Under the licensing agreement, BeiGene has obtained an exclusive license to develop, and commercialize SYH2039 globally for the treatment of advanced or metastatic MTAP-deleted solid tumors.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 12, 2024

                            Lead Product(s) : SYH2039

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : CSPC Zhongqi Pharmaceutical Technology

                            Deal Size : $150.0 million

                            Deal Type : Licensing Agreement

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                            07

                            BeiGene

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                            BeiGene

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                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            European Commission Approves BeiGene’s TEVIMBRA for Advanced Esophageal and Gastric Cancer

                            Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                            Product Name : Tevimbra

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 27, 2024

                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            BeiGene

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                            Lead Product(s) : Decoy20,Tislelizumab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Indaptus Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Indaptus Partners with BeiGene for Cancer Treatment Combination Trials

                            Details : The collaboration aims to advance human clinical evaluation of the combination of BeiGene's anti-PD-1 antibody, Tevimbra (tislelizumab), with Indaptus’ Decoy20, a novel treatment for cancer.

                            Product Name : Decoy20

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            October 22, 2024

                            Lead Product(s) : Decoy20,Tislelizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Indaptus Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            BeiGene

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                            BeiGene

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                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BeiGene’s TEVIMBRA® Receives Positive CHMP Opinions for Gastric/Esophageal Cancer

                            Details : Tevimbra (tislelizumab) is a uniquely designed humanized IgG4 PD-1 mAb, being evaluated for the treatment of first-line gastric or gastroesophageal junction cancers.

                            Product Name : Tevimbra

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 21, 2024

                            Lead Product(s) : Tislelizumab,Oxaliplatin,Cisplatin

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            BeiGene

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                            Lead Product(s) : ABT-301,Tislelizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : Anbogen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Anbogen, BeiGene Collaborate on Colorectal Cancer Combo Therapy in Taiwan

                            Details : The collaboration will evaluate the combination of Anbogen's HDAC inhibitor, ABT-301, with BeiGene's anti-PD-1 antibody Tevimbra (tislelizumab), in pMMR or MSS metastatic colorectal cancer.

                            Product Name : ABT-301

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 27, 2024

                            Lead Product(s) : ABT-301,Tislelizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : Anbogen Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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