Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Belite Releases DRAGON Phase 3 Tinlarebant Interim Results
Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 27, 2025
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Belite Bio Doses First Patient in Phase 2/3 Trial of Tinlarebant for Stargardt Disease
Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 09, 2024
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering
Belite Bio Announces $25 Million Registered Direct Offering
Details : Proceeds will fund the clinical development of LBS-008 (tinlarebant), a novel oral therapy aimed at reducing eye toxins that cause Stargardt Disease and contribute to GA in advanced dry AMD.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 25, 2024
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Belite Submits PMDA Application for Tinlarebant Trial in Japan for Stargardt Disease
Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 22, 2024
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Belite Bio Doses First Subject in Pivotal Phase 3 PHOENIX Trial Evaluating Oral Tinlarebant for GA
Details : LBS-008 (tinlarebant) is a novel oral therapy which is intended to reduce the accumulation of toxins in the eye that cause STGD1 and contribute to GA, or advanced Dry AMD.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 27, 2023
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LBS-008 (tinlarebant) is an orally administered tablet, once daily retinol binding protein 4 (RBP4) antagonist designed to lower levels of ocular vitamin-A based toxins implicated in STGD1.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 24, 2023
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : SVB Securities
Deal Size : $30 million
Deal Type : Public Offering
Details : Belite Bio intends to use the net proceeds of the offering for clinical trials and further clinical development of LBS-008 (tinlarebant), a novel oral therapy intended as an early intervention to prevent the accumulation of vitamin A-based toxins (bisret...
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 30, 2023
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : SVB Securities
Deal Size : $30 million
Deal Type : Public Offering
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : The Benchmark Company
Deal Size : $40.6 million
Deal Type : Public Offering
Belite Bio Announces Partial Exercise of Over-Allotment Option in Initial Public Offering
Details : Belite expects to use the net proceeds from the offering to fund the Phase 3 clinical trial of LBS-008 for STGD1, further clinical development of LBS-008 for dry AMD, working capital and other general corporate purposes.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 05, 2022
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : The Benchmark Company
Deal Size : $40.6 million
Deal Type : Public Offering
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : LBS-008 (tinlarebant) is a novel oral therapy intended as an early intervention to prevent the accumulation of vitamin A-based toxins (bisretinoids) that cause STGD1 and contribute to pathogenesis in Dry AMD.
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 18, 2022
Lead Product(s) : Tinlarebant
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Belite Bio Receives Approval of LBS-008 Phase 3 Clinical Trial in China
Details : Preliminary data from the Phase 2 trial of LBS-008 (tinlarebant) at the first 6-month interval shows that 8 of the 13 patients (or 61.5%) recorded a gain in best-corrected visual acuity (BCVA) in at least one eye, including 2 patients who recorded a BCVA...
Product Name : LBS-008
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 16, 2022
Lead Product(s) : Tinlarebant
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable