[{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Ophthalmology","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Securities"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Benchmark Company","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small 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Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"},{"orgOrder":0,"company":"Belite Bio","sponsor":"The Benchmark Company","pharmaFlowCategory":"D","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ The Benchmark Company","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ The Benchmark Company"},{"orgOrder":0,"company":"Belite Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Tinlarebant","moa":"RBP4","graph1":"Genetic Disease","graph2":"Phase III","graph3":"Belite Bio","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Belite Bio \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Belite Bio \/ Inapplicable"}]

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                          01

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 27, 2025

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          October 09, 2024

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Proceeds will fund the clinical development of LBS-008 (tinlarebant), a novel oral therapy aimed at reducing eye toxins that cause Stargardt Disease and contribute to GA in advanced dry AMD.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          April 25, 2024

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Undisclosed

                          Deal Size : $25.0 million

                          Deal Type : Public Offering

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                          04

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is a novel Retinol-binding protein 4 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of Stargardt Disease.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 22, 2024

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is a novel oral therapy which is intended to reduce the accumulation of toxins in the eye that cause STGD1 and contribute to GA, or advanced Dry AMD.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 27, 2023

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is an orally administered tablet, once daily retinol binding protein 4 (RBP4) antagonist designed to lower levels of ocular vitamin-A based toxins implicated in STGD1.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 24, 2023

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Belite Bio intends to use the net proceeds of the offering for clinical trials and further clinical development of LBS-008 (tinlarebant), a novel oral therapy intended as an early intervention to prevent the accumulation of vitamin A-based toxins (bisret...

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          May 30, 2023

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : SVB Securities

                          Deal Size : $30 million

                          Deal Type : Public Offering

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                          08

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Belite expects to use the net proceeds from the offering to fund the Phase 3 clinical trial of LBS-008 for STGD1, further clinical development of LBS-008 for dry AMD, working capital and other general corporate purposes.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 05, 2022

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : The Benchmark Company

                          Deal Size : $40.6 million

                          Deal Type : Public Offering

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                          09

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : LBS-008 (tinlarebant) is a novel oral therapy intended as an early intervention to prevent the accumulation of vitamin A-based toxins (bisretinoids) that cause STGD1 and contribute to pathogenesis in Dry AMD.

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 18, 2022

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AACR Annual meeting
                          Not Confirmed
                          AACR Annual meeting
                          Not Confirmed

                          Details : Preliminary data from the Phase 2 trial of LBS-008 (tinlarebant) at the first 6-month interval shows that 8 of the 13 patients (or 61.5%) recorded a gain in best-corrected visual acuity (BCVA) in at least one eye, including 2 patients who recorded a BCVA...

                          Product Name : LBS-008

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          September 16, 2022

                          Lead Product(s) : Tinlarebant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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