Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bellicum Discontinues Phase 1/2 Trials and Initiates Evaluation of Strategic Alternatives
Details : BPX-601 incorporates high-performance GoCAR-T™ technology designed to target and treat solid tumors expressing prostate stem cell antigen (PSCA). It is being discontinued following the company’s assessment of BPX-601 risk/benefit profile in combinati...
Brand Name : BPX-601
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 14, 2023
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BPX-601 is our first clinical candidate incorporating our high-performance GoCAR-Tâ„¢ technology designed to target and treat solid tumors expressing prostate stem cell antigen (PSCA).
Brand Name : BPX-601
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 19, 2023
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : MTS Securities
Deal Size : $35.0 million
Deal Type : Private Placement
Details : Proceeds from the financing will be used to support ongoing clinical development of BPX-601 and BPX-603, are designed to be more efficacious CAR-T cell products capable of overriding key immune inhibitory mechanisms.
Brand Name : BPX-601
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 06, 2021
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : MTS Securities
Deal Size : $35.0 million
Deal Type : Private Placement
Lead Product(s) : Cellular Therapy,Inducible Caspase-9,Rimiducid
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Bellicum and MD Anderson Announce Additional License Agreement for Use of CaspaCIDe® Safety Switch
Details : Under this agreement, MD Anderson will have the option to incorporate CaspaCIDe into certain cellular therapy programs. The CaspaCIDe switch consists of the CID-binding domain coupled to the signaling domain of caspase-9, an enzyme that is part of the ap...
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $5.0 million
September 01, 2021
Lead Product(s) : Cellular Therapy,Inducible Caspase-9,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : The University of Texas MD Anderson Cancer Center
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : BPX-603,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bellicum Enrolls First Patient in Phase 1/2 Clinical Trial for BPX-603
Details : BPX-603 is Bellicum’s first dual switch GoCAR-T product candidate that incorporates the company’s iMC activation and CaspaCIDe safety switch technologies. Phase 1/2 trial will investigate the safety, tolerability, and clinical activity of BPX-603, ad...
Brand Name : BPX-603
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 10, 2020
Lead Product(s) : BPX-603,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bellicum Reports Clinical Hold Placed on BPX-601 Phase 1/2 Clinical Trial
Details : The FDA is taking this action due to the death of a pancreatic cancer patient in the trial reported to the agency by the company. The clinical investigator and Bellicum classified the patient death as unrelated to BPX-601 and rimiducid.
Brand Name : BPX-601
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 07, 2020
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bellicum Announces Interim BPX-601 Data and Corporate Restructuring
Details : Findings from the first four patients treated with BPX-601 followed by repeat rimiducid dosing showed evidence of rimiducid-mediated CAR-T cell activation. Clinically meaningful efficacy as measured by RECIST criteria was not observed.
Brand Name : BPX-601
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 29, 2020
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-603
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BPX-603 is the company’s first dual-switch GoCAR-T® product candidate, which incorporates both the company’s iMC activation and CaspaCIDe® safety switch technologies.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 15, 2020
Lead Product(s) : BPX-603
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
MD Anderson Research Freeze Stops Production of Bellicum Drugs
Details : Bellicum is currently involved in 12 active studies, including a phase 1/2 trial of BPX-601 CAR-T cells in advanced solid tumors that express high levels of PSCA.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 17, 2020
Lead Product(s) : BPX-601,Rimiducid
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bellicum Presents New Translational Data for BPX-601 at ASCO GI Cancers Symposium
Details : A cohort treated with BPX-601 and a single dose of rimiducid showed immunomodulation in both the periphery and tumor microenvironment.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 24, 2020
LOOKING FOR A SUPPLIER?