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Find Clinical Drug Pipeline Developments & Deals by Benitec Biopharma

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                          01

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The net proceeds from the proposed financing will support the clinical development of BB-301, which is being evaluated for Oculopharyngeal Muscular Dystrophy.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 25, 2025

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Leerink Partners

                          Deal Size : $30.0 million

                          Deal Type : Public Offering

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                          02

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The company intends to use proceeds for BB-301's clinical development, evaluated in early-stage trials for oculopharyngeal muscular dystrophy treatment.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 18, 2024

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Citizens JMP

                          Deal Size : $40.0 million

                          Deal Type : Private Placement

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                          03

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : BB-301 is a modified AAV9 capsid expressing a bifunctional construct for co-expressing codon-optimized PABPN1 & siRNAs against mutant PABPN1, evaluated for treating oculopharyngeal muscular dystrophy.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          April 18, 2024

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : BB-301 is a Cell and Gene therapy drug designed for Oculopharyngeal Muscular Dystrophy Related Dysphagia, utilizing the PABPN1 gene as a replacer and administered via intramuscular injection.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          November 30, 2023

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The company intends to use the net proceeds to support the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB-301 for the treatment of dysphagia associated with oculopharyngeal muscular dystrophy.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 08, 2023

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : JMP Securities

                          Deal Size : $30.0 million

                          Deal Type : Public Offering

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                          06

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The company intends to use the net proceeds to support the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB-301 for the treatment of dysphagia associated with oculopharyngeal muscular dystrophy.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 08, 2023

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : JMP Securities

                          Deal Size : $30.0 million

                          Deal Type : Public Offering

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                          07

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : BB-301 is a novel, modified AAV9 capsid expressing bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 and two small inhibitory RNAs against mutant PABPN1 is currently in development for Oculopharyngeal...

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          June 26, 2023

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : BB-301 is currently in development for Oculopharyngeal Muscular Dystrophy. BB-301 results in robust inhibition of mutant PABPN1 and concomitant replacement of the codon-optimized PABPN1 protein. The treatment restores muscle strength and muscle weight.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 23, 2023

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The company intends to use the proceeds for development of BB-301, including the natural history lead-in study and Phase 1b/2a BB-301 treatment study, for continued advancement of development activities, for general corporate purposes and for strategic g...

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 09, 2022

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : IND Enabling

                          Sponsor : JMP Securities

                          Deal Size : $18.0 million

                          Deal Type : Public Offering

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                          10

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The Company intends to use the net proceeds from this financing for the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB301 treatment study.

                          Product Name : BB-301

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 16, 2022

                          Lead Product(s) : BB-301

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : IND Enabling

                          Sponsor : JMP Securities

                          Deal Size : $18.0 million

                          Deal Type : Public Offering

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