Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : Leerink Partners
Deal Size : $30.0 million
Deal Type : Public Offering
Benitec Biopharma Inc. Announces Pricing of $30 Million Common Stock Offering
Details : The net proceeds from the proposed financing will support the clinical development of BB-301, which is being evaluated for Oculopharyngeal Muscular Dystrophy.
Product Name : BB-301
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
March 25, 2025
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : Leerink Partners
Deal Size : $30.0 million
Deal Type : Public Offering
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Benitec Reports Positive Interim Data for BB-301 in OPMD Trial
Details : BB-301 is a modified AAV9 capsid expressing a bifunctional construct for co-expressing codon-optimized PABPN1 & siRNAs against mutant PABPN1, evaluated for treating oculopharyngeal muscular dystrophy.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 18, 2024
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : Citizens JMP
Deal Size : $40.0 million
Deal Type : Private Placement
Benitec Biopharma Announces Oversubscribed Private Placement Financing of $40.0 Million
Details : The company intends to use proceeds for BB-301's clinical development, evaluated in early-stage trials for oculopharyngeal muscular dystrophy treatment.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 18, 2024
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : Citizens JMP
Deal Size : $40.0 million
Deal Type : Private Placement
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BB-301 is a Cell and Gene therapy drug designed for Oculopharyngeal Muscular Dystrophy Related Dysphagia, utilizing the PABPN1 gene as a replacer and administered via intramuscular injection.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 30, 2023
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : JMP Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Benitec Biopharma Inc. Announces Closing of $30 Million Underwritten Public Offering
Details : The company intends to use the net proceeds to support the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB-301 for the treatment of dysphagia associated with oculopharyngeal muscular dystrophy.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 11, 2023
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : JMP Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I/ Phase II
Sponsor : JMP Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Benitec Biopharma Inc. Announces Pricing of $30 Million Underwritten Public Offering
Details : The company intends to use the net proceeds to support the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB-301 for the treatment of dysphagia associated with oculopharyngeal muscular dystrophy.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 08, 2023
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I/ Phase II
Sponsor : JMP Securities
Deal Size : $30.0 million
Deal Type : Public Offering
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BB-301 is a novel, modified AAV9 capsid expressing bifunctional construct promoting co-expression of both codon-optimized Poly-A Binding Protein Nuclear-1 and two small inhibitory RNAs against mutant PABPN1 is currently in development for Oculopharyngeal...
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 26, 2023
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Benitec Biopharma Enrolls First OPMD Subject into the Clinical Development Program
Details : BB-301 is currently in development for Oculopharyngeal Muscular Dystrophy. BB-301 results in robust inhibition of mutant PABPN1 and concomitant replacement of the codon-optimized PABPN1 protein. The treatment restores muscle strength and muscle weight.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 23, 2023
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : IND Enabling
Sponsor : JMP Securities
Deal Size : $18.0 million
Deal Type : Public Offering
Benitec Biopharma Inc. Announces Closing of $18 Million Underwritten Public Offering
Details : The Company intends to use the net proceeds from this financing for the clinical development of BB-301, including the natural history lead-in study and the Phase 1b/2a BB301 treatment study.
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 16, 2022
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : IND Enabling
Sponsor : JMP Securities
Deal Size : $18.0 million
Deal Type : Public Offering
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Study Phase : IND Enabling
Sponsor : JMP Securities
Deal Size : $18.0 million
Deal Type : Public Offering
Benitec Biopharma Inc. Announces Pricing of $18 Million Underwritten Public Offering
Details : The company intends to use the proceeds for development of BB-301, including the natural history lead-in study and Phase 1b/2a BB-301 treatment study, for continued advancement of development activities, for general corporate purposes and for strategic g...
Product Name : BB-301
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 12, 2022
Lead Product(s) : BB-301
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : IND Enabling
Sponsor : JMP Securities
Deal Size : $18.0 million
Deal Type : Public Offering