Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : BPGbio
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BPM 31510, the company’s lead drug candidate, acts by targeting the mitochondrial machinery and tumor microenvironment (TME) to create a metabolic shift in cancer cells, leading to cancer cell death.
Brand Name : BPM 31510
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2023
Lead Product(s) : Ubidecarenone,Temozolomide,Vitamin K1
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : BPGbio
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ubidecarenone,Vitamin K1,Temozolomide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Abstract titled "Comprehensive molecular pharmacodynamic assessment identifies response markers of intermediary metabolism associated with BPM31510-IV treatment in advanced glioblastoma multiforme patients" will be presented at the ASCO meeting.
Brand Name : BPM31510
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 02, 2021
Lead Product(s) : Ubidecarenone,Vitamin K1,Temozolomide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ubidecarenone
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BERG To Conduct Phase Two Trial For Treatment Of Deadly Glioblastoma Multiforme [GBM]
Details : Preclinical evidence in an aggressive orthotopic model of GBM suggests that pre-treatment (priming) followed by co-administration of BPM31510 in combination with standard of care, such as radiation and chemotherapy, led to an increase overall survival ra...
Brand Name : BPM31510
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 22, 2021
Lead Product(s) : Ubidecarenone
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ubidecarenone
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : AdventHealth
Deal Size : Undisclosed
Deal Type : Collaboration
BERG Deepens Research Collaboration With AdventHealth To Advance Aging, Metabolism and Nash Research
Details : The partnership is comprised of separate investigations that employ BERG’s Interrogative Biology® platform to examine potential biomarker signatures of age-related disease. This also includes Phase II trial of BPM31510 on platelet and skeletal muscle ...
Brand Name : BPM31510
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 15, 2020
Lead Product(s) : Ubidecarenone
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : AdventHealth
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BPM 31510-IV (ubidecarenone) also known as coenzyme Q10 used in advanced refractory pancreatic ductal adenocarcinoma and identified two potential biomarkers overall survival and progressive disease.
Brand Name : BPM31510
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 18, 2020
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Initial results showed efficacy in patient's refractory to chemotherapy regimens and identification of potential biomarkers of survival guided by the use of the BERG Interrogative Biology® platform.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 27, 2020
Lead Product(s) : Ubidecarenone,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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