Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BerGenBio Announces Safety Data from Dose Escalation Phase 1b in First Line NSCLC Patients
Details : BGB 324 (bemcentinib) is an AXL inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of STK11 mutated NSCLC.
Brand Name : BGB 324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 07, 2024
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
BerGenBio Collaborates with Tempus to Accelerate STK11m NSCLC Development
Details : Through the collaboration, BerGenBio will advance the selective AXL inhibitor, BGB 324 (bemcentinib) for the treatment of non-small cell lung cancer patients with stk11 mutations.
Brand Name : BGB 324
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 20, 2024
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BerGenBio Selects 2nd Dose in Phase 2a STK11m Non-Small Lung Cancer Trial
Details : BGB 324 (bemcentinib) is an AXL inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of STK11 mutated NSCLC.
Brand Name : BGB 324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 29, 2024
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BerGenBio Initiates Phase 2a In First Line NSCLC Patients With STK11 Mutation
Details : BGB 324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL). It is being evaluated for the treatment of STK11 mutated Non-Small Lung Cancer.
Brand Name : BGB 324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 20, 2024
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BerGenBio Presents New Preclinical Data for Bemcentinib in Severe Respiratory Infections
Details : BGB324 (bemcentinib) is a first-in-class oral AXL inhibitor, currently evaluated in preclinical studies for treating Respiratory Syncytial Virus infections.
Brand Name : BGB324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 07, 2024
Lead Product(s) : Bemcentinib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BGB324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL) a promising therapeutic target for serious diseases. It is being developed for the treament of NSCLC.
Brand Name : BGB324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 09, 2023
Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BGB324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL) a promising therapeutic target for serious diseases. It is being investigated for non-small cell lung cancer (NSCLC).
Brand Name : BGB324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 15, 2023
Lead Product(s) : Bemcentinib,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Meteva AS
Deal Size : Undisclosed
Deal Type : Financing
BerGenBio ASA Secures NOK 100 Million Shareholder Loan Facility from Meteva AS
Details : The facility will enable BerGenBio to continue its previously announced focused strategy of advancing its lead compound bemcentinib (BGB324) in 1st line Non-Small Cell Lung Cancer (NSCLC) and hospitalized COVID-19 patients.
Brand Name : BGB324
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 25, 2022
Lead Product(s) : Bemcentinib,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Meteva AS
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Mipasetamab Uzoptirine,Gemcitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : ADC Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ADCT-601 (mipasetamab uzoptirine) is composed of a humanized monoclonal antibody that binds to human AXL (licensed from BerGenBio), conjugated using GlycoConnect™ technology (licensed from Synaffix BV) to a linker with a pyrrolobenzodiazepine (PBD)-dim...
Brand Name : ADCT-601
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 27, 2022
Lead Product(s) : Mipasetamab Uzoptirine,Gemcitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : ADC Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bemcentinib
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Complete data analysis confirms that the primary endpoint of improved clinical response and key secondary endpoints were met in a subprotocol under the platform ACCORD2 study where bemcentinib was added to standard of care therapy.
Brand Name : BGB324
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 26, 2022
Lead Product(s) : Bemcentinib
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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