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    [{"orgOrder":0,"company":"BerGenBio ASA","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"NORWAY","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bemcentinib","moa":"AXL kinase","graph1":"Oncology","graph2":"Phase II","graph3":"BerGenBio ASA","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"BerGenBio ASA \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"BerGenBio ASA \/ Not Applicable"},{"orgOrder":0,"company":"BerGenBio ASA","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"NORWAY","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bemcentinib","moa":"Tyrosine-protein kinase receptor UFO","graph1":"Infections and Infectious Diseases","graph2":"Phase II","graph3":"BerGenBio 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Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"NORWAY","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Bemcentinib","moa":"","graph1":"Technology","graph2":"Approved","graph3":"BerGenBio ASA","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"BerGenBio ASA \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"BerGenBio ASA \/ Not Applicable"},{"orgOrder":0,"company":"BerGenBio ASA","sponsor":"Tempus","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"NORWAY","productType":"Small molecule","year":"2024","type":"Collaboration","leadProduct":"Bemcentinib","moa":"","graph1":"Technology","graph2":"Approved","graph3":"BerGenBio 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    Find Clinical Drug Pipeline Developments & Deals by BerGenBio ASA

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                            01

                            BerGenBio ASA

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                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BerGenBio Announces Safety Data from Dose Escalation Phase 1b in First Line NSCLC Patients

                            Details : BGB 324 (bemcentinib) is an AXL inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of STK11 mutated NSCLC.

                            Brand Name : BGB 324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 07, 2024

                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Tempus

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            BerGenBio Collaborates with Tempus to Accelerate STK11m NSCLC Development

                            Details : Through the collaboration, BerGenBio will advance the selective AXL inhibitor, BGB 324 (bemcentinib) for the treatment of non-small cell lung cancer patients with stk11 mutations.

                            Brand Name : BGB 324

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            August 20, 2024

                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Tempus

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BerGenBio Selects 2nd Dose in Phase 2a STK11m Non-Small Lung Cancer Trial

                            Details : BGB 324 (bemcentinib) is an AXL inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of STK11 mutated NSCLC.

                            Brand Name : BGB 324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 29, 2024

                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BerGenBio Initiates Phase 2a In First Line NSCLC Patients With STK11 Mutation

                            Details : BGB 324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL). It is being evaluated for the treatment of STK11 mutated Non-Small Lung Cancer.

                            Brand Name : BGB 324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 20, 2024

                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            BerGenBio ASA

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                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BerGenBio Presents New Preclinical Data for Bemcentinib in Severe Respiratory Infections

                            Details : BGB324 (bemcentinib) is a first-in-class oral AXL inhibitor, currently evaluated in preclinical studies for treating Respiratory Syncytial Virus infections.

                            Brand Name : BGB324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 07, 2024

                            Lead Product(s) : Bemcentinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BerGenBio Announces First Patient Dosed in Phase 1b/2a Trial Evaluating Bemcentinib in 1st Line Non-Small Cell...

                            Details : BGB324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL) a promising therapeutic target for serious diseases. It is being developed for the treament of NSCLC.

                            Brand Name : BGB324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 09, 2023

                            Lead Product(s) : Bemcentinib,Pembrolizumab,Pemetrexed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            BerGenBio ASA

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                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BerGenBio Announces Positive Data From Phase 2 Trial of Bemcentinib in Combination with Pembrolizumab in 2L+ N...

                            Details : BGB324 (bemcentinib) is a first-in-class, selective, oral once-a-day inhibitor of AXL receptor tyrosine kinase (AXL) a promising therapeutic target for serious diseases. It is being investigated for non-small cell lung cancer (NSCLC).

                            Brand Name : BGB324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 15, 2023

                            Lead Product(s) : Bemcentinib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            BerGenBio ASA

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                            BerGenBio ASA

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                            Lead Product(s) : Bemcentinib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Meteva AS

                            Deal Size : Undisclosed

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            BerGenBio ASA Secures NOK 100 Million Shareholder Loan Facility from Meteva AS

                            Details : The facility will enable BerGenBio to continue its previously announced focused strategy of advancing its lead compound bemcentinib (BGB324) in 1st line Non-Small Cell Lung Cancer (NSCLC) and hospitalized COVID-19 patients.

                            Brand Name : BGB324

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 25, 2022

                            Lead Product(s) : Bemcentinib,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Meteva AS

                            Deal Size : Undisclosed

                            Deal Type : Financing

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                            09

                            BerGenBio ASA

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                            BerGenBio ASA

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                            Lead Product(s) : Mipasetamab Uzoptirine,Gemcitabine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : ADC Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            ADC Therapeutics Doses First Patient in Phase 1b Clinical Trial of ADCT-601 Targeting AXL as a Single Agent an...

                            Details : ADCT-601 (mipasetamab uzoptirine) is composed of a humanized monoclonal antibody that binds to human AXL (licensed from BerGenBio), conjugated using GlycoConnect™ technology (licensed from Synaffix BV) to a linker with a pyrrolobenzodiazepine (PBD)-dim...

                            Brand Name : ADCT-601

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 27, 2022

                            Lead Product(s) : Mipasetamab Uzoptirine,Gemcitabine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : ADC Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Bemcentinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Bergenbio Announces Complete Data Analysis of Accord2 Phase II Bemcentinib Study in Hospitalized Covid-19 Pati...

                            Details : Complete data analysis confirms that the primary endpoint of improved clinical response and key secondary endpoints were met in a subprotocol under the platform ACCORD2 study where bemcentinib was added to standard of care therapy.

                            Brand Name : BGB324

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 26, 2022

                            Lead Product(s) : Bemcentinib

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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