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                          01

                          Lead Product(s) : Bevacizumab

                          Therapeutic Area : Oncology

                          Study Phase : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Versavo (bevacizumab) is a VEGF A inhibitor indicated for various cancers, including metastatic colorectal cancer and advanced non-squamous non-small cell lung cancer.

                          Product Name : Versavo

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 19, 2024

                          Lead Product(s) : Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Details : Mirvetuximab was readily combined and well tolerated with standard dosing of carboplatin and bevacizumab, with a manageable adverse event (AE) profile as anticipated for this triplet based on the side effect profiles of each agent.

                          Product Name : Elahere

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          September 17, 2020

                          Lead Product(s) : Mirvetuximab Soravtansine,Bevacizumab,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Immunogen

                          03

                          Details : The combination of mirvetuximab soravtansine with bevacizumab in this cohort demonstrates encouraging anti-tumor activity with a favorable tolerability profile, particularly among the subset of patients with high levels of FRα expression.

                          Product Name : Elahere

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          May 13, 2020

                          Lead Product(s) : Mirvetuximab Soravtansine,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Immunogen

                          04

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : The net proceeds will used to support the company's late-stage product Olvi-Vec (olvimulogene nanivacirepvec), which is being evaluated for the treatment of Platinum r/r Ovarian Cancer.

                          Product Name : Olvi-Vec

                          Product Type : Microorganism

                          Upfront Cash : Undisclosed

                          March 25, 2025

                          Lead Product(s) : Olvimulogene Nanivacirepvec,Bevacizumab,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Titan Partners Group

                          Deal Size : $10.5 million

                          Deal Type : Public Offering

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                          05

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Olvi-Vec (olvimulogene nanivacirepvec), is a proprietary, modified strain of the vaccinia virus. It is being evaluated for the treatment of platinum resistant/refractory ovarian cancer.

                          Product Name : Olvi-Vec

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          March 25, 2025

                          Lead Product(s) : Olvimulogene Nanivacirepvec,Bevacizumab,Carboplatin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Loqtorzi (toripalimab) is an approved anti-PD-1 monoclonal antibody, in combination with bevacizumab for the first-line treatment of advanced hepatocellular carcinoma

                          Product Name : Loqtorzi

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 23, 2025

                          Lead Product(s) : Toripalimab,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : IO-108 antibody is being evaluated in combination with atezolizumab and bevacizumab for the treatment of locally advanced hepatocellular carcinoma.

                          Product Name : IO-108

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 27, 2025

                          Lead Product(s) : IO-108,Atezolizumab,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : F. Hoffmann-La Roche

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Casdozo (casdozokitug), a selective and potent IL-27-targeting antibody, in combination with atezolizumab and bevacizumab in patients with unresectable locally advanced or metastatic HCC.

                          Product Name : Casdozo

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : Casdozokitug,Atezolizumab,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : NKT2152, a highly potent, selective & orally bioavailable small molecule HIF2α inhibitor, in combination with standard-of-care in the first-line treatment of patients with advanced or metastatic HCC.

                          Product Name : NKT2152

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 21, 2025

                          Lead Product(s) : NKT2152,Atezolizumab,Bevacizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BePharma
                          Not Confirmed
                          BePharma
                          Not Confirmed

                          Details : Lytenava (bevacizumab gamma) is a recombinant humanized mAb that selectively binds with high affinity to VEGF. It is indicated for the treatment of wet age-related macular degeneration.

                          Product Name : Lytenava

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 16, 2025

                          Lead Product(s) : Bevacizumab

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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