Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Prexigebersen
Therapeutic Area : Nutrition and Weight Loss
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Holdings Initiates Development of Therapeutic Program for Treatment of Obesity
Details : BP1001-A works by binding directly to Grb2 mRNA, preventing its translation into the Grb2 protein. It is currently being evaluated for the treatment of obesity and related metabolic diseases.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 08, 2024
Lead Product(s) : Prexigebersen
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Reports Solid Tumor Patient Response to BP1001-A Treatment
Details : BP1001-A, a modified product of prexigebersen, incorporates the same drug substance as prexigebersen but has a slightly altered formulation designed to enhance NP properties for solid tumors.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 21, 2024
Lead Product(s) : Prexigebersen,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Completes Higher Dose Cohort in BP1002 Trial for Acute Myeloid Leukemia
Details : BP1002 (L-Bcl-2) is a liposomal Bcl-2 antisense oligonucleotide in Phase 1 development for treating relapsed/refractory lymphoma and chronic lymphocytic leukemia (CLL) patients.
Brand Name : L-Bcl-2
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 18, 2024
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Completes First Dose Cohort in BP1002 Trial for Lymphoma and CLL Patients
Details : BP1002 (L-Bcl-2) is a liposomal Bcl-2 antisense oligonucleotide in Phase 1 development for treating relapsed/refractory lymphoma and chronic lymphocytic leukemia (CLL) patients.
Brand Name : BP1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 10, 2024
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1002 is a Bcl-2 inhibitor that targets the BH3 domain of the Bcl-2 protein. It is being evaluated in combination with decitabine for the treatment of refractory/relapsed acute myeloid leukemia.
Brand Name : BP1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 14, 2023
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen,Decitabine,Ventoclax
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1001 (prexigebersen) is a neutral liposome incorporated with nuclease-resistant, hydrophobic P-ethoxy antisense oligodeoxynucleotides targeted to Grb2 mRNA, which is investigated for the treatment of acute myeloid leukemia.
Brand Name : BP1001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 01, 2023
Lead Product(s) : Prexigebersen,Decitabine,Ventoclax
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1001-A is a modified drug product with the same drug substance as Bio-Path’s lead drug candidate, prexigebersen, but includes formulation enhancements to produce smaller drug nanoparticles, being investigated for Solid Tumors.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 17, 2023
Lead Product(s) : Prexigebersen
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Liposomal Grb2 Antisense Oligonucleotide,Paclitaxel
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1001-A is a modified drug product with the same drug substance as prexigebersen but includes formulation enhancements to produce smaller drug nanoparticles.
Brand Name : BP1001-A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 07, 2022
Lead Product(s) : Liposomal Grb2 Antisense Oligonucleotide,Paclitaxel
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BP1002 targets the protein Bcl-2, which is responsible for driving cell survival in up to 60% of all cancers. By targeting Bcl-2 at the mRNA level rather than the protein, BP1002 may overcome and prevent some of the mechanisms of resistance that affect v...
Brand Name : BP1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 24, 2022
Lead Product(s) : BP1002,Decitabine
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BP1003
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bio-Path Holdings to Present at the 2022 American Association for Cancer Research Annual Meeting
Details : BP1003 (liposomal STAT3 antisense), an RNAi nanoparticle DNA targeting STAT3, a protein associated with increased PDAC severity and poorer survival in patients with PDAC, in combination with paclitaxel or fluorouracil used as a potential treatment agains...
Brand Name : BP1003
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : BP1003
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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