[{"orgOrder":0,"company":"BioArctic AB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"SWEDEN","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Ban2401","moa":"Amyloid beta plaque","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Not Applicable"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"BioArctic AB","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"NORWAY","productType":"Undisclosed","year":"2020","type":"Agreement","leadProduct":"Undisclosed","moa":"Apolipoprotein E","graph1":"Neurology","graph2":"Discovery","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"BioArctic AB \/ BioArctic","highestDevelopmentStatusID":"2","companyTruncated":"BioArctic AB \/ BioArctic"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Lecanemab","moa":"","graph1":"Neurology","graph2":"Approved","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ BioArctic","highestDevelopmentStatusID":"12","companyTruncated":"BioArctic AB \/ BioArctic"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta plaque","graph1":"Neurology","graph2":"Approved","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous infusion","sponsorNew":"BioArctic AB \/ BioArctic AB","highestDevelopmentStatusID":"12","companyTruncated":"BioArctic AB \/ BioArctic AB"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Undisclosed","year":"2021","type":"Not Applicable","leadProduct":"AD1503","moa":"","graph1":"Neurology","graph2":"Discovery","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"BioArctic AB \/ Not Applicable","highestDevelopmentStatusID":"2","companyTruncated":"BioArctic AB \/ Not Applicable"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta protein A4","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous infusion","sponsorNew":"BioArctic AB \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Not Applicable"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta plaque","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous infusion","sponsorNew":"BioArctic AB \/ Eisai","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Eisai"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta plaque","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Eisai","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Eisai"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not 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Applicable"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta plaque","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Not Applicable"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta protein A4","graph1":"Neurology","graph2":"Phase III","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Eisai","highestDevelopmentStatusID":"10","companyTruncated":"BioArctic AB \/ Eisai"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Eisai","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Lecanemab","moa":"Amyloid beta","graph1":"Neurology","graph2":"Approved","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Bioarctic","highestDevelopmentStatusID":"12","companyTruncated":"BioArctic AB \/ Bioarctic"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2022","type":"Termination","leadProduct":"ABBV-0805","moa":"Alpha synuclein","graph1":"Neurology","graph2":"Phase I","graph3":"BioArctic AB","amount2":0.76000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0.76000000000000001,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ AbbVie","highestDevelopmentStatusID":"6","companyTruncated":"BioArctic AB \/ AbbVie"},{"orgOrder":0,"company":"BioArctic AB","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"ABBV-0805","moa":"Alpha synuclein","graph1":"Neurology","graph2":"Phase I","graph3":"BioArctic AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"BioArctic AB \/ Not 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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta. It is indicated for the treatment of Alzheimer’s disease.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 30, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Recipient : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta. It is indicated for the treatment of Alzheimer’s disease.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 26, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta. It is indicated for the treatment of Alzheimer’s disease.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 11, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The agreement aims to evaluate BAN2802, a potential new treatment combining BioArctic's proprietary BrainTransporter™ technology with an undisclosed Alzheimer drug candidate.

                          Brand Name : BAN2802

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 20, 2024

                          Lead Product(s) : BAN2802

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Eisai Inc

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab-irmb) is a humanized IgG1 monoclonal antibody targeting amyloid-beta, being evaluated for IV maintenance dosing in early Alzheimer's disease treatment.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 31, 2024

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab-irmb) is a humanized IgG1 monoclonal antibody directed against aggregated soluble and insoluble amyloid-beta forms. It is indicated for the treatment of Alzheimer’s disease.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 09, 2024

                          Lead Product(s) : Lecanemab-irmb

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Leqembi (lecanemab-irmb) is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta (Aβ). It is indicated for the treatment of Alzheimer’s disease.

                          Brand Name : Leqembi

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 27, 2023

                          Lead Product(s) : Lecanemab-irmb

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Lecanemab is an investigational humanized monoclonal antibody for AD. Lecanemab selectively binds and eliminates soluble, toxic amyloid-beta (Aβ) aggregates (protofibrils) that are thought to contribute to the neurotoxicity in AD.

                          Brand Name : BAN2401

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 23, 2022

                          Lead Product(s) : Lecanemab

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase III

                          Recipient : Eisai

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The PD-BT2238 project is a second-generation alpha-synuclein antibody, combining an oligomer-selective alpha-synuclein antibody with BioArctic's Brain Transporter technology, designed to improve brain exposure.

                          Brand Name : PD-BT2238

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 17, 2022

                          Lead Product(s) : PD-BT2238

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Blood-brain barrier protects brain from foreign substances by restricting passage of these substances into brain. The patented technologyhas been developed to facilitate the transport of biopharmaceuticals across this barrier, thereby potentially improvi...

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Not Applicable

                          November 14, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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