Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biofrontera Completes Database Lock in Ameluz® PDT Study for sBCC
Details : Ameluz (5-aminolevulinic acid hydrochloride) is a topical gel that acts as a photosensitizing agent during photodynamic therapy. It is used primarily for the treatmentsuperficial basal cell carcinoma.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 14, 2024
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA OKs Triple-Tube Use of Ameluz Gel for Skin Cancer Treatment
Details : Ameluz is the only PDT photosensitizer indicated by the FDA for both lesion-directed and field-directed treatment of Actinic Keratosis.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 07, 2024
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Roth Capital Partners
Deal Size : $16.0 million
Deal Type : Private Placement
Biofrontera Inc. Announces Closing Of Private Placement Of Up To $16.0 Million
Details : The Company intends to fund ongoing activities related to expediting the development and approval of additional indications for Ameluz (aminolevulinic acid hydrochloride) to treat actinic keratoses.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 23, 2024
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Roth Capital Partners
Deal Size : $16.0 million
Deal Type : Private Placement
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AMELUZ® (aminolevulinic acid hydrochloride) topical gel, 10%, a porphyrin precursor, in combination with photodynamic therapy using BF-RhodoLED® lamp, is indicated for lesion-directed and field-directed treatment of actinic keratoses.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 21, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biofrontera Inc. Announces Notice of Allowance for Nanoemulsion Composition-of-Matter U.S. Patent
Details : AMELUZ (aminolevulinic acid hydrochloride) topical gel, 10%, a porphyrin precursor, in combination with photodynamic therapy using BF-RhodoLED® lamp, is indicated for the lesion-directed and field-directed treatment of actinic keratoses of mild-to-moder...
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 06, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Ameluz (Aminolevulinic Acid Hydrochloride) is utilized along with photodynamic therapy (PDT) provided by the Company’s proprietary lamp devices to form Ameluz®-PDT.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 24, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Roth Capital Partners
Deal Size : $9.4 million
Deal Type : Private Placement
Biofrontera Inc. Announces Closing of $9.4 Million Private Placement
Details : The new funds will aid to expand the market presence and strategic position. Together with broadening the product label through three clinical trials running in parallel with licensing partner, this will unravel the enormous market potential Ameluz® has...
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 19, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Roth Capital Partners
Deal Size : $9.4 million
Deal Type : Private Placement
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biofrontera Launches New Patient-Focused Websites for Ameluz® and Xepi®
Details : AMELUZ (aminolevulinic acid hydrochloride) topical gel, a porphyrin precursor, in combination with photodynamic therapy using BF-RhodoLED® lamp, is indicated for lesion-directed and field-directed treatment of actinic keratoses of mild-to-moderate sever...
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 21, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Ameluz® is Biofrontera’s first FDA-approved flagship prescription drug is used in combination with the RhodoLED® lamp series for the treatment of Actinic Keratoses, and the topical antibiotic drug Xepi®.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 17, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biofrontera AG Announces Progress of Phase III Study for the Treatment of sBCC with Ameluz
Details : Phase III clinical study for the treatment of superficial basal cell carcinoma with Ameluz photodynamic therapy (aminolevulinic acid hydrochloride) in combination with the BF-RhodoLED lamp enrolled 186 patient in the study is approved by FDA.
Brand Name : Ameluz
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 01, 2022
Lead Product(s) : Aminolevulinic Acid HCl
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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