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(omaveloxolone), the First Therapy to Treat Friedreich's Ataxia","therapeuticArea":"Genetic Disease","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Small molecule","productStatus":"Approved","date":"February 2024","url1":"","url2":"","graph1":"Genetic Disease","graph2":"Approved"},{"orgOrder":0,"company":"Biogen","sponsor":"AbCellera","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"AbCellera to Collaborate with Biogen to Discover Therapeutic Antibodies for Neurological Conditions","therapeuticArea":"Neurology","highestDevelopmentStatus":"Discovery Platform","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"March 2024","url1":"","url2":"","graph1":"Neurology","graph2":"Discovery Platform"},{"orgOrder":0,"company":"Biogen","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"CHMP Issues Positive Opinion 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therapy","therapeuticArea":"Neurology","highestDevelopmentStatus":"Approved","country":"U.S.A","productType":"Large molecule","productStatus":"Approved","date":"May 2024","url1":"","url2":"","graph1":"Neurology","graph2":"Approved"}]
Find Clinical Drug Pipeline Developments & Deals by Biogen
Through the acquisition, Biogen will have access to pipeline a range of immune-mediated diseases, including MOR202 (felzartamab), being evaluated for treating primary membranous nephropathy.
Leqembi (lecanemab) is an IgG1 monoclonal antibody directed against aggregated soluble (protofibril) and insoluble forms of amyloid-beta. It is indicated for the treatment of Alzheimer’s disease.
EC has granted approval for TOFIDENCE, a biosimilar monoclonal antibody referencing ROACTEMRA, for moderate to severe active rheumatoid arthritis, systemic juvenile idiopathic arthritis, etc.
Qalsody (tofersen), an ASO designed to bind to SOD1 mRNA to reduce SOD1 protein production. FDA granted accelerated approval for amyotrophic lateral sclerosis having SOD1 gene mutation.
Through the acquisition, Biogen will have access to pipeline-in-a-product across a range of immune-mediated diseases, including MOR202 (felzartamab), a potential first-in-class therapeutic candidate being evaluated for treating primary membranous nephropathy.
BIIB105 (ION541) is an investigational oligonucleotide designed to reduce the production of the ataxin-2 (ATXN2) protein. It is being evaluated for the treatment of amyotrophic lateral sclerosis.
Tofidence (tocilizumab-biosimilar) is a recombinant IL-6 receptor inhibitor, monoclonal antibody. It is being evaluated for moderate to severe active rheumatoid arthritis, polyarticular juvenile idiopathic arthritis, systemic juvenile idiopathic arthritis & COVID-19.
The collaboration aims to discover antibodies for a novel target that enables the delivery of biotherapeutics to the brain for indications in neuroscience.
Spinraza (nusinersen) is a survival motor neuron-2 (SMN2)-directed antisense
oligonucleotide indicated for the treatment of spinal muscular atrophy (SMA)
in pediatric and adult patients.
Qalsody (tofersen) is an antisense oligonucleotide designed to bind to SOD1 mRNA to reduce SOD1 protein production. The U.S. FDA granted accelerated approval for QALSODY to treat amyotrophic lateral sclerosis in adults who have a mutation in the SOD1 gene.