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                          Medlab Asia & Asia Health
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                          Medlab Asia & Asia Health
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                          Details : The collaboration aims to leverage Neomorph's proprietary molecular glue discovery platform to expedite the identification and validation of new small-molecule therapeutics for Alzheimer’s disease.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 29, 2024

                          Lead Product(s) : Molecular Glue Degrader-based Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Discovery Platform

                          Recipient : Neomorph

                          Deal Size : $1,450.0 million

                          Deal Type : Collaboration

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : MOR202 (felzartamab) is an investigational monoclonal antibody designed to specifically target and deplete CD38+ cells. It is being evaluated for late AMR in kidney transplant recipients.

                          Brand Name : MOR202

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 09, 2024

                          Lead Product(s) : Felzartamab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Spinraza (nusinersen) is a survival motor neuron-2 (SMN2)-directed antisense oligonucleotide indicated for the treatment of spinal muscular atrophy (SMA) in pediatric and Toddlers.

                          Brand Name : Spinraza

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 09, 2024

                          Lead Product(s) : Nusinersen Sodium

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Following the termination of the agreement, Sage will regain full ownership of the SAGE-324 from Biogen. This asset is being evaluated for the treatment of patients with essential tremors.

                          Brand Name : SAGE-324

                          Molecule Type : Small molecule

                          Upfront Cash : $1,525.0 million

                          September 26, 2024

                          Lead Product(s) : SAGE-324

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Recipient : Sage Therapeutics

                          Deal Size : $1,525.0 million

                          Deal Type : Termination

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : CDP7657 (dapirolizumab pegol), a novel Fc-free anti-CD40L drug candidate, investigated in people living with moderate-to-severe systemic lupus erythematosus (SLE).

                          Brand Name : CDP7657

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 24, 2024

                          Lead Product(s) : Dapirolizumab Pegol

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Recipient : UCB Pharma S.A

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Opuviz (aflibercept) is a vascular endothelial growth factor (VEGF) inhibitor indicated for the treatment of patients with Neovascular (Wet) Age-Related Macular Degeneration

                          Brand Name : Opuviz

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 20, 2024

                          Lead Product(s) : Aflibercept

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Approved

                          Recipient : Samsung Bioepis

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The collaboration aims to investigate the use of C4T’s novel protein degradation platform to discover and develop potential new treatments for Alzheimer’s & Parkinson’s disease.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          September 10, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Neurology

                          Highest Development Status : Discovery

                          Recipient : C4 Therapeutics

                          Deal Size : $415.0 million

                          Deal Type : Collaboration

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                          08

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Lantesens (nusinersen) is a generic of Spinraza, which is SMN2-directed antisense oligonucleotide investigated for the treatment of spinal muscular atrophy (SMA) in pediatrics.

                          Brand Name : Spinraza

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 04, 2024

                          Lead Product(s) : Nusinersen Sodium

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : SAGE-324 (BIIB124) is an investigational oral neuroactive steroid (NAS) GABAA receptor positive allosteric modulator (PAM) being developed for the treatment of essential tremor.

                          Brand Name : SAGE-324

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 24, 2024

                          Lead Product(s) : BIIB124

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II/ Phase III

                          Recipient : Sage Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Through a licensing agreement, GSK will acquire full rights from Curevac of Flu mRNA (GSK4382276) to develop, manufacture, and commercialize globally mRNA candidate vaccines for influenza.

                          Brand Name : Flu mRNA

                          Molecule Type : Vaccine

                          Upfront Cash : $429.2 million

                          July 03, 2024

                          Lead Product(s) : GSK4382276A

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Recipient : CureVac

                          Deal Size : $1,556.0 million

                          Deal Type : Licensing Agreement

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