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Pharmaceuticals","sponsor":"Pfizer Inc","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"Rimegepant Sulfate","moa":"CGRP","graph1":"Neurology","graph2":"Approved","graph3":"Biohaven Pharmaceuticals","amount2":11.6,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":11.6,"dosageForm":"Tablet, Orally Disintegrating","sponsorNew":"Biohaven Pharmaceuticals \/ Pfizer","highestDevelopmentStatusID":"12","companyTruncated":"Biohaven Pharmaceuticals \/ Pfizer"},{"orgOrder":0,"company":"Biohaven Pharmaceuticals","sponsor":"Channel BioSciences","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"INDIA","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"BHV-7000","moa":"Kv7 channel","graph1":"Neurology","graph2":"Preclinical","graph3":"Biohaven Pharmaceuticals","amount2":1.24,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":1.24,"dosageForm":"","sponsorNew":"Biohaven Pharmaceuticals \/ Biohaven Pharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Biohaven Pharmaceuticals \/ Biohaven Pharmaceuticals"},{"orgOrder":0,"company":"Biohaven Pharmaceuticals","sponsor":"Pfizer Inc","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"Rimegepant Sulfate","moa":"CGRP receptor","graph1":"Neurology","graph2":"Approved","graph3":"Biohaven Pharmaceuticals","amount2":11.6,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":11.6,"dosageForm":"Oral Disintegrating Tablet","sponsorNew":"Biohaven Pharmaceuticals \/ Pfizer Inc","highestDevelopmentStatusID":"12","companyTruncated":"Biohaven Pharmaceuticals \/ Pfizer 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Disease","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Troriluzole","moa":"","graph1":null,"graph2":null,"graph3":"Biohaven Pharmaceuticals","amount2":0,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"amount2New":0,"dosageForm":"","sponsorNew":"Biohaven Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":null,"companyTruncated":"Biohaven Pharmaceuticals \/ Not Applicable"}]

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                          01

                          PackExpo
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                          Details : BHV-2100 is a potentially first-in-class, potent, selective, orally administered TRPM3 antagonist, a novel, non-sedating non-opioid treatment for migraine and pain.

                          Brand Name : BHV-2100

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 30, 2024

                          Lead Product(s) : BHV-2100

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV-4157 (troriluzole ) is a third-generation novel prodrug that modulates glutamate, the most abundant excitatory neurotransmitter in the human body. It is being evaluated for Spinocerebellar Ataxia.

                          Brand Name : BHV-4157

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 23, 2024

                          Lead Product(s) : Troriluzole

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV-1510 is a novel Trop-2 directed antibody drug conjugate, which is currently being evaluated for the treatment of advanced or metastatic epithelial tumors.

                          Brand Name : BHV-1510

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 30, 2024

                          Lead Product(s) : BHV-1510

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV2000 (taldefgrobep-alpha) is a fully human anti-myostatin recombinant protein that lowers free myostatin and acts as an Activin 2b receptor antagonist with the myostatin-taldefgrobep complex, thereby blocking myostatin signaling in skeletal muscles.

                          Brand Name : BHV2000

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 14, 2023

                          Lead Product(s) : Taldefgrobep-alfa

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV-7000 (formerly known as KB-3061). BHV-7000 is a potent activator of Kv7.2/Kv7.3, which are key subunits involved in neuronal signaling and in regulating the hyperexcitable state in focal epilepsy.

                          Brand Name : BHV-7000

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 05, 2023

                          Lead Product(s) : BHV-7000

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV2000 (taldefgrobep-alpha) is a fully human anti-myostatin recombinant protein that lowers free myostatin and acts as an Activin 2b receptor antagonist with the myostatin-taldefgrobep complex, thereby blocking myostatin signaling in skeletal muscles.

                          Brand Name : BHV2000

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          July 31, 2023

                          Lead Product(s) : Taldefgrobep-alfa

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV-7000 (formerly known as KB-3061). BHV-7000 is a potent activator of Kv7.2/Kv7.3, which are key subunits involved in neuronal signaling and in regulating the hyperexcitable state in focal epilepsy.

                          Brand Name : BHV-7000

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 27, 2023

                          Lead Product(s) : BHV-7000

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Vydura (also known as Rimegepant) is an oral lyophilisate and is the first calcitonin gene-related peptide (CGRP) receptor antagonist migraine therapy to be accepted by the SMC.

                          Brand Name : Vydura

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 10, 2023

                          Lead Product(s) : Rimegepant Sulfate

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Recipient : Pfizer Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : Under the agreement, Biohaven and Highlightll will coordinate clinical development across global regions for BHV-8000 (previously TLL-041), an oral, brain-penetrant, dual inhibitor of TYK2 and JAK1 for the treatment of brain disorders.

                          Brand Name : BHV-8000

                          Molecule Type : Small molecule

                          Upfront Cash : $10.0 million

                          March 22, 2023

                          Lead Product(s) : BHV-8000

                          Therapeutic Area : Neurology

                          Highest Development Status : Preclinical

                          Recipient : Hangzhou Highlightll Pharmaceutical

                          Deal Size : $970.0 million

                          Deal Type : Licensing Agreement

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                          10

                          PackExpo
                          Not Confirmed
                          PackExpo
                          Not Confirmed

                          Details : BHV2000 (taldefgrobep-alpha) is a fully human anti-myostatin recombinant protein that lowers free myostatin and acts as an Activin 2b receptor antagonist with the myostatin-taldefgrobep complex, thereby blocking myostatin signaling in skeletal muscles.

                          Brand Name : BHV2000

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 21, 2023

                          Lead Product(s) : Taldefgrobep-alfa

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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