Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bionomics Initiates Phase 3 AFFIRM-1 Trial with BNC210 for Social Anxiety Disorder
Details : BNC210 is a negative allosteric modulator of the α7 nicotinic acetylcholine receptor, which is being evaluated for the treatment of Social Anxiety Disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 18, 2024
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Leerink Partners
Deal Size : $70.0 million
Deal Type : Private Placement
Bionomics Limited Announces Private Placement of up to $70.0 Million
Details : The net proceeds will be used to advance the clinical development of BNC210, Aplha-7 receptor NAM. Currently, it is being evlauted for the treatment of social anxiety disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 31, 2024
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Leerink Partners
Deal Size : $70.0 million
Deal Type : Private Placement
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bionomics Reports Full Analysis from ATTUNE Phase 2b Trial of BNC210 in PTSD Patients
Details : BNC210 is a negative allosteric modulator of the α7 nicotinic acetylcholine receptor, which is being evaluated for the treatment of PTSD and Social Anxiety Disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 21, 2024
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of social anxiety disorder and post-traumatic stress disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 16, 2023
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 28, 2023
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MK-4334,Donepepzil
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : $526.0 million
Deal Type : Collaboration
Details : Under the collaboration, MK-4334, a novel clinical candidate was developed by MSD and derived from Bionomics’ original α7 nAChR PAM candidate (BNC375) for the treatment of cognitive disorders like Alzheimer’s Disease.
Brand Name : MK-4334
Molecule Type : Small molecule
Upfront Cash : $20.0 million
September 14, 2023
Lead Product(s) : MK-4334,Donepepzil
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : $526.0 million
Deal Type : Collaboration
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BNC210 is a negative allosteric modulator of the alpha7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 23, 2023
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BNC210 is a negative allosteric modulator of the α7 nicotinic acetylcholine receptor under development for the treatment of SAD and post-traumatic stress disorder.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 27, 2023
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Bionomics Reports Topline Results in PREVAIL Phase 2 Study of BNC210 in Social Anxiety Disorder
Details : BNC210 has a novel mechanism of action that involves negative allosteric modulation of the α7 nicotinic acetylcholine receptor. The Company is continuing analysis of the PREVAIL dataset and is assessing next steps for the development of BNC210 in SAD.
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 19, 2022
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Aegis Capital Corp.
Deal Size : $5.0 million
Deal Type : Public Offering
Details : BNC210 is an oral, proprietary, selective negative allosteric modulator of the α7 nicotinic acetylcholine receptor, for the acute treatment of Social Anxiety Disorder (“SAD”) and chronic treatment of Post-Traumatic Stress Disorder (PTSD).
Brand Name : BNC210
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 21, 2022
Lead Product(s) : BNC210
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Aegis Capital Corp.
Deal Size : $5.0 million
Deal Type : Public Offering
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