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                            Lead Product(s) : Gotistobart

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : OncoC4

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Puts Partial Hold on BioNTech-OncoC4 Phase 3 Trial

                            Details : ONC-392 (gotistobart) is a humanized anti-CTLA4 IgG1 monoclonal antibody, which is currently being evaluated for the treatment of metastatic non-small cell lung cancers.

                            Brand Name : ONC-392

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 18, 2024

                            Lead Product(s) : Gotistobart

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : OncoC4

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery

                            Recipient : Tempus

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Tempus Announces Real World Data Collaboration with BioNTech

                            Details : The collaboration leverages Tempus' robust multimodal datasets, analytical support and computational biology expertise in support of BioNTech’s next-generation oncology pipeline.

                            Brand Name : Undisclosed

                            Molecule Type : Undisclosed

                            Upfront Cash : Undisclosed

                            September 04, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery

                            Recipient : Tempus

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Lead Product(s) : BNT162b2

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Recipient : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer and BioNTech Get FDA Approval for Omicron-Adapted COVID-19 Vaccine

                            Details : Comirnaty JN.1 (Omi JN.1), a COVID-19 mRNA vaccine has achieved positive CHMP opinion by EMA for Omicron JN.1 lineage of SARS-CoV-2 infection in individuals 6 months of age and older.

                            Brand Name : Comirnaty JN.1

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            August 22, 2024

                            Lead Product(s) : BNT162b2

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Recipient : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : YL202

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioNTech Says FDA Lifts Partial Hold on Its Cancer Drug Trial

                            Details : YL202 is a HER3 modulator antibody drug conjugate, which is currently being evaluated for the treatment of non small cell lung cancer & breast cancer.

                            Brand Name : YL202

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 19, 2024

                            Lead Product(s) : YL202

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Quadrivalent Influenza modRNA Vaccine,COVID-19 mRNA Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Recipient : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer and BioNTech Update mRNA Combo Vaccine Program for Flu and COVID-19

                            Details : Pfizer and BioNTech are developing a combination vaccine that targets both influenza and COVID-19, utilizing their advanced mRNA technology.

                            Brand Name : Influenza and COVID-19 Combination A

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            August 16, 2024

                            Lead Product(s) : Quadrivalent Influenza modRNA Vaccine,COVID-19 mRNA Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Recipient : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Acasunlimab,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Genmab

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            Genmab Takes Full Control of Acasunlimab Development Program

                            Details : Through the termination, responsibility for the continued development and potential commercialization of GEN1046 (acasunlimab), which is being evaluated for PD-L1-positive non small cell lung cancer.

                            Brand Name : GEN1046

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 05, 2024

                            Lead Product(s) : Acasunlimab,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Genmab

                            Deal Size : Undisclosed

                            Deal Type : Termination

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                            Lead Product(s) : Acasunlimab,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Genmab

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioNTech Ends Work on Genmab-Partnered Bispecific Antibody Acasunlimab

                            Details : GEN1046/BNT311 (acasunlimab), an investigational bispecific antibody (PD-L1x4-1BB), as monotherapy and in combination with pembrolizumab in patients with PDL(1)-positive mNSCLC.

                            Brand Name : GEN1046

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 05, 2024

                            Lead Product(s) : Acasunlimab,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Genmab

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : BNT111,Cemiplimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioNTech Announces Positive Phase 2 Results for BNT111 in Advanced Melanoma

                            Details : BNT111 is an mRNA-based off-the-shelf cancer immunotherapy candidate. It is being evaluated for the treatment of patients with unresectable stage III or IV melanoma.

                            Brand Name : BNT111

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            July 30, 2024

                            Lead Product(s) : BNT111,Cemiplimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : BNT162b2

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Pfizer and BioNTech Get Positive CHMP Opinion for Omicron COVID-19 Vaccine

                            Details : Comirnaty JN.1 (Omi JN.1), a COVID-19 mRNA vaccine has achieved positive CHMP opinion by EMA for Omicron JN.1 lineage of SARS-CoV-2 infection in individuals 6 months of age and older.

                            Brand Name : Comirnaty JN.1

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            June 27, 2024

                            Lead Product(s) : BNT162b2

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Pfizer Inc

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : DB-1311

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : DualityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioNTech and DualityBio Receive FDA Fast Track for BNT324/DB-1311 in Prostate Cancer

                            Details : BNT324/DB-1311 is a next-generation topoisomerase-I-inhibitor-based ADC candidate being investigated for metastatic castration-resistant prostate cancer.

                            Brand Name : BNT324

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 24, 2024

                            Lead Product(s) : DB-1311

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : DualityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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