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    [{"orgOrder":0,"company":"Biorestorative Therapies","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Musculoskeletal","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"BRTX-100","moa":"","graph1":"Orthopedics\/Orthopedic Surgery","graph2":"Phase II","graph3":"Biorestorative Therapies","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Orthopedics","amount2New":0,"dosageForm":"","sponsorNew":"Biorestorative Therapies \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Biorestorative Therapies \/ Not Applicable"},{"orgOrder":0,"company":"Biorestorative Therapies","sponsor":"PRC Clinical","pharmaFlowCategory":"D","therapeuticArea":"Orthopedics\/Orthopedic Surgery","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Agreement","leadProduct":"Hypoxic Cultured Mesenchymal Stem Cells","moa":"","graph1":"Orthopedics\/Orthopedic 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                            01

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BioRestorative Therapies Reports Positive Preliminary Phase 2 BRTX-100 Clinical Data

                            Details : BRTX-100 a novel cell-based therapeutic engineered to target areas of the body that have little blood flow. It is designed to offer a non-surgical treatment for chronic lumbar disc diseases.

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 13, 2024

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : Exosome-based Therapy

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BioRestorative Enhances Metabolic Program with Exosome-Based Biologic Targeting Obesity

                            Details : Company is developing a novel exosome-based biologic program for the treatment of obesity and aims to initiate first-in-human clinical studies before the end of the year.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 08, 2024

                            Lead Product(s) : Exosome-based Therapy

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Clears Phase 2 BRTX-100 Clinical Study Protocol Amendment

                            Details : BRTX-100 a novel cell-based therapeutic engineered to target areas of the body that have little blood flow. It is designed to offer a non-surgical treatment for chronic lumbar disc diseases.

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            April 16, 2024

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Galen Patient Recruitment

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            BioRestorative Therapies Partners with Galen to Accelerate Enrollment in BRTX-100 Trial

                            Details : The partnership aims to accelerate the completion of patient enrollment in the ongoing Phase 2 study of BioRestorative's primary clinical candidate, BRTX-100, for chronic lumbar disc disease.

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 08, 2024

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Galen Patient Recruitment

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BioRestorative Therapies Announces Activation of Northwell Health in the Company's Phase 2 Clinical Trial Targ...

                            Details : BRTX-100 contains patient’s bone marrow autologous cultured mesenchymal stem cells. It is a novel cell-based therapeutic, engineered to target areas of the body that have little blood flow. It is currently being evaluated for chronic lumbar disc diseas...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 08, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Titan Partners Group

                            Deal Size : $2.1 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            BioRestorative Therapies Announces $2.1 Million Registered Direct Offering

                            Details : The Company intends to use the proceeds for its clinical trials with respect to its lead cell therapy candidate, BRTX-100, intended for the treatment of chronic lumbar disc disease, and for pre-clinical research and development with respect to its metabo...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            July 11, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Titan Partners Group

                            Deal Size : $2.1 million

                            Deal Type : Public Offering

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                            07

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            BioRestorative Therapies' Drug Candidate BRTX-100 Passes Safety Test With Flying Colors, Moves Ahead With Phas...

                            Details : BRTX-100 contains patient’s bone marrow autologous cultured mesenchymal stem cells. It is a novel cell-based therapeutic, engineered to target areas of the body that have little blood flow. It is currently being evaluated for chronic lumbar disc diseas...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            July 07, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Biorestorative Therapies

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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioRestorative Therapies Receives Unanimous Recommendation from Data Safety Monitoring Board (DSMB) to Continu...

                            Details : BRTX-100 contains patient’s bone marrow autologous cultured mesenchymal stem cells. It is a novel cell-based therapeutic, engineered to target areas of the body that have little blood flow. It is currently being evaluated for chronic lumbar disc diseas...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 27, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Pharmtech & Ingredients
                            Not Confirmed
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                            • WHO-GMP
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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            BioRestorative Therapies Announces Key Milestone of Dosing Completion in Safety Cohort of Phase 2 Trial Target...

                            Details : BRTX-100 contains patient’s bone marrow autologous cultured mesenchymal stem cells. It is a novel cell-based therapeutic, engineered to target areas of the body that have little blood flow. It is currently being evaluated for chronic lumbar disc diseas...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            June 12, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Biorestorative Therapies

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                            Biorestorative Therapies

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                            Pharmtech & Ingredients
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                            • WHO-GMP
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                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Phase II

                            Sponsor : Northwell Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            BioRestorative Therapies and Northwell Health Enter into Agreement to Participate in the Company’s Phase 2 C...

                            Details : Under the agreement, Northwell will participate in BioRestorative Therapies ongoing Phase 2 clinical trial, evaluating BRTX-100, a novel cell-based therapeutic engineered to target areas of the body that have little blood flow, targeting chronic lumber d...

                            Brand Name : BRTX-100

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            May 08, 2023

                            Lead Product(s) : BRTX-100

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Phase II

                            Sponsor : Northwell Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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