Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BioSenic Releases New Analysis of Phase 2 Data for Arsenic Trioxide in cGvHD
Details : Arscimed (arsenic trioxide) is a thioredoxin reductase 1 inhibitor small molecule drug candidate, which is being evaluated for the treatment of chronic graft versus host disease.
Brand Name : Arscimed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 18, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Phebra
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Medsenic Subsidiary Signs Licensing Agreement with Phebra PTY Ltd
Details : Medsenic and Phebra should facilitate the final steps of manufacturing, clinical confirmation of efficacy and subsequent commercialization of oral ArsciCor (arsenic trioxide) in cGvHD.
Brand Name : ArsciCor
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 02, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Phebra
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : ABO Securities
Deal Size : $2.2 million
Deal Type : Agreement
BioSenic Signs a New Subscription Agreement for a Maximum of EUR 2.1M in Convertible Bonds
Details : The proceeds of the financing will essentially contribute to continuing to advance the clinical development of Arscimed (arsenic trioxide) in the treatment of chronic graft versus host disease.
Brand Name : Arscimed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 21, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : ABO Securities
Deal Size : $2.2 million
Deal Type : Agreement
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Gestys Santé Biotech
Deal Size : $0.5 million
Deal Type : Private Placement
BioSenic Raises €500,000 in Private Placement of New Shares with Established New Investors
Details : BioSenic will use proceeds for a Phase 3 trial with Arscimed (oral arsenic trioxide) for first-line treatment of chronic graft-versus-host disease.
Brand Name : Arscimed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 02, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Gestys Santé Biotech
Deal Size : $0.5 million
Deal Type : Private Placement
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Preclinical
Recipient : Phebra
Deal Size : Undisclosed
Deal Type : Agreement
BioSenic Reaches Agreement with Phebra on Oral Arsenic Trioxide Development for cGvHD
Details : The agreement aims for the development of the first oral formulation of ArsciCor (arsenic troxide) in the field of several targeted autoimmune diseases, including for cGvHD treatment.
Brand Name : ArsciCor
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 15, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Recipient : Phebra
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : ABO Securities
Deal Size : Undisclosed
Deal Type : Financing
BioSenic Signs a New Subscription Agreement for a Maximum of EUR 1.2M in Convertible Bonds
Details : The proceeds from the financing will contribute to advancing clinical development of BioSenic’s lead asset its ATO product, Arscimed (arsenic trioxide), for treating chronic graft versus host disease.
Brand Name : Arscimed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 08, 2024
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : ABO Securities
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : ATO (arsenic trioxide) is administered daily by IV infusions, which is investigated for the treatment of Graft Versus Host Disease, Systemic Sclerosis, Systemic Lupus Erythematosus and infectious disease.
Brand Name : OATO
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 27, 2023
Lead Product(s) : Arsenic Trioxide
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Allogeneic Bone Cell Therapy
Therapeutic Area : Orthopedics/Orthopedic Surgery
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BioSenic Puts Phase IIb ALLOB Trial on Hold
Details : ALLOB is an allogeneic cell therapy platform consisting of human allogeneic bone-forming cells derived from ex-vivo cultured bone marrow mesenchymal stromal cells (MSC) from healthy adult donors. It is being developed for delayed-union fractures and spin...
Brand Name : ALLOB
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 19, 2023
Lead Product(s) : Allogeneic Bone Cell Therapy
Therapeutic Area : Orthopedics/Orthopedic Surgery
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Clonidine,Hyaluronic Acid
Therapeutic Area : Musculoskeletal
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BioSenic Reacquires Global IP Rights and Provides Update On JTA-004 Development
Details : JTA-004 consists of a unique mix of plasma proteins, hyaluronic acid, a natural component of knee synovial fluid and a fast-acting analgesic. It was designed to provide added lubrication and protection to the arthritic joint cartilage and to alleviate os...
Brand Name : JTA-004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 17, 2023
Lead Product(s) : Clonidine,Hyaluronic Acid
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Arsenic Trioxide,Metal ion
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Arscimed® (arsenic trioxide), is a able to radically modify the autoimmune cascade and normalise the immune system without causing nonspecific immunosuppressionbeing studied for cGvHD.
Brand Name : Arscimed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 18, 2023
Lead Product(s) : Arsenic Trioxide,Metal ion
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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