Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : OHRO
Deal Size : $12.6 million
Deal Type : Funding
BioVie Secures $12.6M Grant For Long COVID Phase 2 Bezisterim Trial
Details : The fundings aims to support BioVie’s to plan the clinical advancement of NE3107 (bezisterim) for the treatment of neurological symptoms that are associated with long COVID.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
September 16, 2024
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : OHRO
Deal Size : $12.6 million
Deal Type : Funding
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
BioVie Aligns with FDA On Bezisterim Trial For Parkinson’s Disease
Details : NE3107 (bezisterim) is an orally bioavailable, BBB-permeable, insulin-sensitizer that is also anti-inflammatory. It is being evaluated for the treatment of parkinson's disease.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 08, 2024
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : U.S. Department of Defense
Deal Size : $13.1 million
Deal Type : Funding
BioVie Awarded Up to $13.1M from DoD to Study Bezisterim for Long COVID
Details : The funding is intended to support the clinical advancement of the company's investigational product NE3107 (bezisterim), which is currently undergoing evaluation in early-stage trials for Covid-19.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
April 29, 2024
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : U.S. Department of Defense
Deal Size : $13.1 million
Deal Type : Funding
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
BioVie Receives FDA Authorization For Bezisterim in Long COVID Phase 2 Trial
Details : NE3107 (bezisterim) is an orally bioavailable, BBB-permeable, insulin-sensitizer that is also anti-inflammatory. It is not immunosuppressive and has a low risk of drug-to-drug interaction.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 09, 2024
Lead Product(s) : Bezisterim
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NE3107 is an ERK/NF-kappa B Inhibitor small molecule drug candidate, which is currently being evaluated for mild to moderate Alzheimer’s Disease treatment.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 29, 2023
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NE3107 is an oral small molecule, with potential anti-inflammatory, insulin sensitizing, and ERK-binding properties which allows it to selectively inhibit ERK-, NFκB- and TNF-stimulated inflammation.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 26, 2023
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NE3107 is an oral small molecule, with potential anti-inflammatory, insulin sensitizing, and ERK-binding properties which allows it to selectively inhibit ERK-, NFκB- and TNF-stimulated inflammation.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 03, 2023
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Terlipressin Acetate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BIV201 (terlipressin diacetate), a vasopressin agonist, it increases systemic vascular resistance, particularly in the splanchnic area, resulting in a decrease of portal pressure. It reduces ascites fluid buildup.
Product Name : BIV201
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
March 13, 2023
Lead Product(s) : Terlipressin Acetate
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NE3107 is an oral small molecule, with potential anti-inflammatory, insulin sensitizing, and ERK-binding properties which allows it to selectively inhibit ERK-, NFκB- and TNF-stimulated inflammation.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 03, 2023
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NE3107 is an oral small molecule, blood-brain permeable, compound with potential anti-inflammatory, insulin sensitizing, and ERK-binding properties that may allow it to selectively inhibit ERK-, NFκB- and TNF-stimulated inflammation.
Product Name : NE3107
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 29, 2022
Lead Product(s) : Bezisterim
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable