Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BITD401412
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : MSRD
Deal Size : Undisclosed
Deal Type : Agreement
BITT Announces CD40 Otsuka Deal and New NIH Funding For TNFR2 Clinical Trial
Details : MSRD will finance key non-human primate studies for the pre-clinical development of BITT’s CD40 antagonist, BITD401412, in autoimmune diseases, including autoimmune thyroiditis, T1D & IBD.
Brand Name : BITD401412
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 16, 2024
Lead Product(s) : BITD401412
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : MSRD
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : BITT-101
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Funding
BITT Announces NIH Award for Advancement of Anti-CD40 Antibody
Details : The funding will support the preclinical development of BITT’s BITT-101, a novel dominant CD40 antagonist antibody for use in the treatment of Sjögren’s Syndrome.
Brand Name : BITT-101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 31, 2023
Lead Product(s) : BITT-101
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : National Institutes of Health
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : BITT2101
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BITT Announces FDA Acceptance of IND for TNFR2 Antibody
Details : BITT2101 is an investigational, novel, tumor necrosis factor superfamily receptor (TNFSR) antagonist antibody, which is being investigated for the treatment in patients with relapsed or refractory Non-Hodgkin’s lymphomas.
Brand Name : BITT2101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 18, 2023
Lead Product(s) : BITT2101
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BITT-CD4D11
Therapeutic Area : Gastroenterology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
BITT Provides Update on DOMab Platform and CD40 Program
Details : BITT-CD4D11 and BITT-CD4F10, CD40 antagonists, are being developed for indications in autoimmunity and inflammation including Crohn’s disease, inflammatory bowel disease, psoriasis, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus...
Brand Name : BITT-CD4D11
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 13, 2023
Lead Product(s) : BITT-CD4D11
Therapeutic Area : Gastroenterology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BITR2101
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : KBI Biopharma
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement focuses to develop the cell line for BITR2101, BITT’s lead tumor necrosis factor receptor 2 (TNFR2) antagonist antibody for the treatment of cancers and infectious diseases.
Brand Name : BITR2101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 09, 2021
Lead Product(s) : BITR2101
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : KBI Biopharma
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : BITR2101,Tislelizumab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : BeiGene
Deal Size : $125.6 million
Deal Type : Collaboration
Details : BeiGene has secured an option to an exclusive license to develop, manufacture, and commercialize BITT’s TNFR2 antagonist antibodies in Asia (ex-Japan), Australia, and New Zealand. Parties plan to conduct Phase 1 trials of BITR2101 and combination studi...
Brand Name : BITR2101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
February 17, 2021
Lead Product(s) : BITR2101,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : BeiGene
Deal Size : $125.6 million
Deal Type : Collaboration
LOOKING FOR A SUPPLIER?