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GmbH","amount2":0.60999999999999999,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"amount2New":0,"dosageForm":"","sponsorNew":"Boehringer Ingelheim GmbH \/ Boehringer Ingelheim GmbH","highestDevelopmentStatusID":null,"companyTruncated":"Boehringer Ingelheim GmbH \/ Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"Boehringer Ingelheim GmbH","sponsor":"Zealand Pharma","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"","productType":"Peptide","year":"2024","type":"Not Applicable","leadProduct":"Survodutide","moa":"","graph1":null,"graph2":null,"graph3":"Boehringer Ingelheim GmbH","amount2":0,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"amount2New":0,"dosageForm":"","sponsorNew":"Boehringer Ingelheim GmbH \/ Boehringer Ingelheim Gmbh","highestDevelopmentStatusID":null,"companyTruncated":"Boehringer Ingelheim GmbH \/ Boehringer Ingelheim Gmbh"}]

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                            01

                            Boehringer Ingelheim GmbH

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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Macrocycle-based Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Circle Pharma

                            Deal Size : $607.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Boehringer Ingelheim and Circle Pharma Announce Precision Cancer Treatment Pact

                            Details : The collaboration aims to develop a first-in-class cyclin inhibitor that can halt the growth of cancer cells potentially offering hope to those living with hard-to-treat cancers.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 09, 2024

                            Lead Product(s) : Macrocycle-based Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Circle Pharma

                            Deal Size : $607.0 million

                            Deal Type : Collaboration

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                            02

                            Boehringer Ingelheim GmbH

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                            euroPLX 86 Munich
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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Survodutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase III

                            Recipient : Zealand Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Zealand, Boehringer Win FDA Breakthrough Status to Treat Fatty Liver

                            Details : BI456906 (survodutide) is a glucagon/GLP-1 receptor dual agonist with a novel mechanism of action. It is being evaluated for the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

                            Brand Name : BI 456906

                            Molecule Type : Peptide

                            Upfront Cash : Not Applicable

                            October 07, 2024

                            Lead Product(s) : Survodutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase III

                            Recipient : Zealand Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : SZN-413

                            Therapeutic Area : Ophthalmology

                            Study Phase : Preclinical

                            Recipient : Surrozen

                            Deal Size : $599.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Surrozen Earns $10 Million Milestone Payment in Retinal Diseases Collaboration

                            Details : Surrozen collaborates with Boehringer to research & develop SZN-413 to treat retinal diseases and will receive an exclusive, worldwide license to develop other Fzd4-specific Wnt-modulating molecules.

                            Brand Name : SZN-413

                            Molecule Type : Large molecule

                            Upfront Cash : $12.5 million

                            September 24, 2024

                            Lead Product(s) : SZN-413

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Preclinical

                            Recipient : Surrozen

                            Deal Size : $599.0 million

                            Deal Type : Collaboration

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                            04

                            Boehringer Ingelheim GmbH

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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Nerandomilast

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Boehringer’s Nerandomilast Meets Primary Endpoint in FIBRONEER™-IPF Study

                            Details : BI 1015550 (nerandomilast) is an investigational oral, preferential inhibitor of phosphodiesterase 4B (PDE4B) that is being studied as a potential treatment for idiopathic pulmonary fibrosis.

                            Brand Name : BI 1015550

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 16, 2024

                            Lead Product(s) : Nerandomilast

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Boehringer Ingelheim GmbH

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                            euroPLX 86 Munich
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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Zongertinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Boehringer’s Zongertinib Shows Efficacy in HER2 Mutated Lung Cancer Patients

                            Details : BI 1810631 (zongertinib) is an investigational oral HER2 tyrosine kinase inhibitor (TKI) in development being investigated in patients with advanced NSCLC with activating HER2 mutations.

                            Brand Name : BI 1810631

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 09, 2024

                            Lead Product(s) : Zongertinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Boehringer Ingelheim GmbH

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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : BI 771716

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Boehringer Ingelheim Advances Treatment for Geographic Atrophy after Phase I Success

                            Details : BI 771716, developed with technology licensed from CDR-Life, is a highly specific antibody fragment of reduced size, enabling an optimized penetration in patients with GA disease pathology.

                            Brand Name : BI 771716

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 05, 2024

                            Lead Product(s) : BI 771716

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Boehringer Ingelheim GmbH

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                            euroPLX 86 Munich
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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Recipient : Nerio Therapeutics

                            Deal Size : $1,300.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Boehringer Buys Nerio Therapeutics for $1.3B to Boost Immuno-Oncology Pipeline

                            Details : Through the acquisition, Boehringer will leverage the Nerio oncology Pipeline, which consists of small molecules that inhibit the PTPN1/2, enhance immune function, and sensitize tumors.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 29, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Recipient : Nerio Therapeutics

                            Deal Size : $1,300.0 million

                            Deal Type : Acquisition

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                            08

                            Boehringer Ingelheim GmbH

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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Spesolimab

                            Therapeutic Area : Dermatology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            CHMP Adopts Positive Opinion for Expanded SPEVIGO® Indications

                            Details : Spevigo (spesolimab) is an IL-36 blocker, given by IV infusion, has been approved by CDSCO as the first treatment option for generalized pustular psoriasis flares in adults.

                            Brand Name : Spevigo

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 29, 2024

                            Lead Product(s) : Spesolimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Boehringer Ingelheim GmbH

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                            euroPLX 86 Munich
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                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : Volasertib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Notable Labs

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Notable Labs Receives FDA Clearance to Proceed Further with Volasertib Phase 2 Study

                            Details : NBL-001 (volasertib) is a PLK-1 inhibitor, small molecule drug candidate. It is being evaluated for the treatment of relapsed/refractory acute myeloid leukemia.

                            Brand Name : NBL-001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 24, 2024

                            Lead Product(s) : Volasertib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Notable Labs

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Boehringer Ingelheim GmbH

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                            Lead Product(s) : BI 770371,Ezabenlimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : OSE Immunotherapeutics SA

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Boehringer Ingelheim and OSE Immunotherapeutics Advance SIRP Cancer Immunology Treatment

                            Details : BI 770371 is a novel anti-SIRPα monoclonal antibody (mAb) targeting both V1 and V2 SIRPα. It is currently in clinical studies for various immuno-oncology diseases like NSCLC, HNSCC & melanoma.

                            Brand Name : BI 770371

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 03, 2024

                            Lead Product(s) : BI 770371,Ezabenlimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : OSE Immunotherapeutics SA

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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