Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Blue Earth Therapeutics Advances rhPSMA-10.1 with Phase 1 Data
Details : 177Lu-rhPSMA-10.1 is an radiohybrid (rh) prostate-specific membrane antigen-targeted radiopharmaceutical. It is being evaluated for treatment of metastatic castrate resistant prostate cancer.
Brand Name : 177Lu-rhPSMA-10.1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 08, 2024
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Seibersdorf Labor
Deal Size : Undisclosed
Deal Type : Partnership
Blue Earth and Seibersdorf Expand Radiopharmaceutical Manufacture Deal
Details : The collaboration will support the progress a Phase 1/2 clinical trial with Actinium 225Ac-rhPSMA-10.1 in treatment of metastatic castrate resistant prostate cancer.
Brand Name : 225Ac-rhPSMA-10.1
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 12, 2024
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Seibersdorf Labor
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : University College London
Deal Size : Undisclosed
Deal Type : Collaboration
Blue Earth Therapeutics Announces Collaboration with UCL for Prostate Cancer Therapy
Details : The collaboration aims to advance the clinical development of company’s investigational product 225Ac-rhPSMA-10.1 for the treatment of metastatic castrate-resistant prostate cancer.
Brand Name : 225Ac-rhPSMA-10.1
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 23, 2024
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : University College London
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Blue Earth Publishes Results from Trial with 177Lu-rhPSMA-10.1 in Prostate Cancer
Details : 177Lu-rhPSMA-10.1 is an investigational radiohybrid (rh) prostate-specific membrane antigen-targeted radiopharmaceutical. It is being evaluated for metastatic castrate resistant prostate cancer.
Brand Name : 177Lu-rhPSMA-10.1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 20, 2024
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In preclinical results to evaluate the binding affinity, lipophilicity, cellular internalization and therapeutic efficacy of 225Ac-rhPSMA-10.1 in preclinical models for the treatment of prostate cancer, using 177Lu-rhPSMA-10.
Brand Name : 225Ac-rhPSMA-10.1
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 11, 2023
Lead Product(s) : 225Ac-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Blue Earth Therapeutics and Blue Earth Diagnostics work closely on the development of 177Lu‐rhPSMA‐10.1. Currently, rhPSMA compounds have not received regulatory approval.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 08, 2022
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Results from preclinical biodistribution studies demonstrated that 177Lu‑rhPSMA-10.1 performed favorably when compared with 177Lu-PSMA-I&T, with an improved tumor:kidney uptake ratio.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 14, 2022
Lead Product(s) : 177Lu-rhPSMA-10.1
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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