Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BBT-877,Pirfenidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Bridge Biotherapeutics Completes Enrollment in Phase 2a Study of BBT-877 for IPF
Details : BBT-877 a novel autotoxin (ATX) inhibitor, small molecule drug candidate which is currently being evaluated for the treatment of idiopathic pulmonary fibrosis.
Product Name : BBT-877
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 29, 2024
Lead Product(s) : BBT-877,Pirfenidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-877,Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Emory University School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Bridge Biotherapeutics Launches Collaboration with Emory To Explore BBT-877 Therapy
Details : A collaboration will assess BBT-877, an ATX inhibitor, combined with anti-PD-1 immunotherapy for NSCLC patients with KRAS and P53 mutations resistant to treatment.
Product Name : BBT-877
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 28, 2024
Lead Product(s) : BBT-877,Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Emory University School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : BBT-877
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : University of Colorado School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Bridge Biotherapeutics Announces Research Collaboration with University Of Colorado
Details : The collaboration focuses on BBT-877, an immuno-oncology cancer treatment, conducting preclinical studies to evaluate its potential in enhancing anti-tumor immunity.
Product Name : BBT-877
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 26, 2024
Lead Product(s) : BBT-877
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : University of Colorado School of Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : BBT-877
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BBT-877 is an orally administered autotaxin enzyme inhibitor which is under development as a treatment for various fibrotic diseases such as idiopathic pulmonary fibrosis (IPF).
Product Name : BBT-877
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 04, 2023
Lead Product(s) : BBT-877
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-207
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BBT-207, a novel epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is designed to inhibit the signaling pathway of EGFR with C797S mutations, which arises due to osimertinib (Tagrisso)-resistant mutations in NSCLC.
Product Name : BBT-207
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 30, 2023
Lead Product(s) : BBT-207
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-877
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BBT-877 is an orally administered autotaxin enzyme inhibitor which is under development as a treatment for various fibrotic diseases such as idiopathic pulmonary fibrosis (IPF).
Product Name : BBT-877
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 25, 2023
Lead Product(s) : BBT-877
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-401
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BBT-401, is a GI-tract restricted small molecule Pellino-1 inhibitor. Pellino serve as scaffold that bind to proteins in inflammatory signaling pathways in various physio-pathological conditions. It is being investiated for inflammatory diseases such as ...
Product Name : BBT-401
Product Type : Peptide
Upfront Cash : Inapplicable
February 20, 2023
Lead Product(s) : BBT-401
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-176,Cetuximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : At its latest presentation to investors, Bridge Biotherapeutics shared interim Phase 1 study data of BBT-176 in advanced NSCLC showing that drug candidate was well-tolerated and demonstrated efficacy against EGFR-mutation positive NSCLC.
Product Name : BBT-176
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 05, 2022
Lead Product(s) : BBT-176,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBT-207
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Bridge Biotherapeutics to Present Preclinical Data of BBT-207 at the AACR 2022 Annual Meeting
Details : Preclinical data suggests that BBT-207, a novel, 4th generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) may have the potential to be positioned as a frontline treatment with the anti-tumor effects in EGFR mutant NSCLC.
Product Name : BBT-207
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 03, 2022
Lead Product(s) : BBT-207
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Scripps Research
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the multi-year collaboration agreement, Scripps will conduct research and development activities, and Bridge Biotherapeutics will retain an exclusive option to acquire worldwide license and patent rights from the research program.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 02, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Scripps Research
Deal Size : Undisclosed
Deal Type : Collaboration