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Find Clinical Drug Pipeline Developments & Deals for BRII-179

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through the acquisition, Brii will get access to focus on the development of VBI-2601 (BRII-179), a protein-based HBV immunotherapeutic candidate intended for the treatment of chronic HBV infection.

                          Brand Name : VBI-2601

                          Molecule Type : Vaccine

                          Upfront Cash : $10.0 million

                          February 13, 2024

                          Lead Product(s) : BRII-179,Elebsiran

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Brii Biosciences

                          Deal Size : $33.0 million

                          Deal Type : Acquisition

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : VBI-2601 (BRII-179) is a novel recombinant, protein-based HBV immunotherapeutic candidate that builds upon the 3-antigen conformation of VBI’s prophylactic 3-antigen HBV vaccine candidate and is designed to target enhanced B-cell and T-cell immunity.

                          Brand Name : VBI-2601

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          September 06, 2023

                          Lead Product(s) : BRII-179,VIR-2218

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Brii Biosciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the collaboration, Brii Bio expanded its exclusive license to VBI-2601 (BRII-179), VBI’s HBV immunotherapeutic candidate, to global rights and acquired an exclusive license for PreHevbri, VBI’s 3-antigen hepatitis B vaccine, in the Asia Pacific...

                          Brand Name : VBI-2601

                          Molecule Type : Vaccine

                          Upfront Cash : $15.0 million

                          July 05, 2023

                          Lead Product(s) : BRII-179

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Brii Biosciences

                          Deal Size : $437.0 million

                          Deal Type : Expanded Collaboration

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : VBI-2601 (BRII-179) is a novel recombinant, protein-based HBV immunotherapeutic candidate that builds upon the 3-antigen conformation of VBI’s prophylactic 3-antigen HBV vaccine candidate and is designed to target enhanced B-cell and T-cell immunity.

                          Brand Name : VBI-2601

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          February 15, 2023

                          Lead Product(s) : BRII-179,VIR-2218

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The data demonstrate that BRII-835 (VIR-2218), an small interfering ribonucleic acid that mediates RNA interference, results in dose-dependent reduction in hepatitis B surface antigen in Chinese patients with chronic HBV infection who received two doses ...

                          Brand Name : VIR-2218

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 31, 2022

                          Lead Product(s) : VIR-2218,BRII-179

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The data demonstrate that BRII-179 (VBI-2601) provokes responses in both B cells (antibodies) and T cells of patients with chronic hepatitis B infection (HBV), and was well tolerated, with no signal detection safety.

                          Brand Name : VBI-2601

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 23, 2021

                          Lead Product(s) : BRII-179

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : BRII-179 (VBI-2601) is a novel recombinant, protein-based immunotherapeutic candidate, which is being developed and led by Brii Bio in partnership with VBI Vaccines (“VBI”) for patients with chronic hepatitis B virus (HBV) infection.

                          Brand Name : VBI-2601

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 09, 2021

                          Lead Product(s) : BRII-179

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : VBI Vaccines

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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