Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : BRII-179,Elebsiran
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Brii Biosciences
Deal Size : $33.0 million
Deal Type : Acquisition
Brii Biosciences Announces Agreement To Acquire VBI's IP Rights In BRII-179
Details : Through the acquisition, Brii will get access to focus on the development of VBI-2601 (BRII-179), a protein-based HBV immunotherapeutic candidate intended for the treatment of chronic HBV infection.
Brand Name : VBI-2601
Molecule Type : Vaccine
Upfront Cash : $10.0 million
February 13, 2024
Lead Product(s) : BRII-179,Elebsiran
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Brii Biosciences
Deal Size : $33.0 million
Deal Type : Acquisition
Lead Product(s) : BRII-179,VIR-2218
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Brii Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VBI-2601 (BRII-179) is a novel recombinant, protein-based HBV immunotherapeutic candidate that builds upon the 3-antigen conformation of VBI’s prophylactic 3-antigen HBV vaccine candidate and is designed to target enhanced B-cell and T-cell immunity.
Brand Name : VBI-2601
Molecule Type : Vaccine
Upfront Cash : Not Applicable
September 06, 2023
Lead Product(s) : BRII-179,VIR-2218
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Brii Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Brii Biosciences
Deal Size : $437.0 million
Deal Type : Expanded Collaboration
Details : Under the collaboration, Brii Bio expanded its exclusive license to VBI-2601 (BRII-179), VBI’s HBV immunotherapeutic candidate, to global rights and acquired an exclusive license for PreHevbri, VBI’s 3-antigen hepatitis B vaccine, in the Asia Pacific...
Brand Name : VBI-2601
Molecule Type : Vaccine
Upfront Cash : $15.0 million
July 05, 2023
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Brii Biosciences
Deal Size : $437.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : BRII-179,VIR-2218
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VBI-2601 (BRII-179) is a novel recombinant, protein-based HBV immunotherapeutic candidate that builds upon the 3-antigen conformation of VBI’s prophylactic 3-antigen HBV vaccine candidate and is designed to target enhanced B-cell and T-cell immunity.
Brand Name : VBI-2601
Molecule Type : Vaccine
Upfront Cash : Not Applicable
February 15, 2023
Lead Product(s) : BRII-179,VIR-2218
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : VIR-2218,BRII-179
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The data demonstrate that BRII-835 (VIR-2218), an small interfering ribonucleic acid that mediates RNA interference, results in dose-dependent reduction in hepatitis B surface antigen in Chinese patients with chronic HBV infection who received two doses ...
Brand Name : VIR-2218
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 31, 2022
Lead Product(s) : VIR-2218,BRII-179
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The data demonstrate that BRII-179 (VBI-2601) provokes responses in both B cells (antibodies) and T cells of patients with chronic hepatitis B infection (HBV), and was well tolerated, with no signal detection safety.
Brand Name : VBI-2601
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 23, 2021
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : VBI Vaccines
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BRII-179 (VBI-2601) is a novel recombinant, protein-based immunotherapeutic candidate, which is being developed and led by Brii Bio in partnership with VBI Vaccines (“VBI”) for patients with chronic hepatitis B virus (HBV) infection.
Brand Name : VBI-2601
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 09, 2021
Lead Product(s) : BRII-179
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : VBI Vaccines
Deal Size : Not Applicable
Deal Type : Not Applicable
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