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    [{"orgOrder":0,"company":"Chimerix","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Brincidofovir","moa":"DNA polymerase","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Chimerix","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Chimerix \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Chimerix \/ Not Applicable"},{"orgOrder":0,"company":"Chimerix","sponsor":"Emergent BioSolutions","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Acquisition","leadProduct":"Brincidofovir","moa":"Viral DNA synthesis","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Chimerix","amount2":0.33000000000000002,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.33000000000000002,"dosageForm":"Tablet","sponsorNew":"Chimerix \/ Emergent BioSolutions","highestDevelopmentStatusID":"12","companyTruncated":"Chimerix \/ Emergent BioSolutions"},{"orgOrder":0,"company":"Chimerix","sponsor":"Emergent BioSolutions","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Agreement","leadProduct":"Brincidofovir","moa":"Viral DNA synthesis","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Chimerix","amount2":0.01,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.01,"dosageForm":"Tablet","sponsorNew":"Chimerix \/ Emergent BioSolutions","highestDevelopmentStatusID":"12","companyTruncated":"Chimerix \/ Emergent BioSolutions"},{"orgOrder":0,"company":"Chimerix","sponsor":"Public Health Agency of Canada","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Agreement","leadProduct":"Brincidofovir","moa":"Viral DNA synthesis","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Chimerix","amount2":0.029999999999999999,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.029999999999999999,"dosageForm":"Tablet","sponsorNew":"Chimerix \/ Public Health Agency of Canada","highestDevelopmentStatusID":"12","companyTruncated":"Chimerix \/ Public Health Agency of Canada"},{"orgOrder":0,"company":"Chimerix","sponsor":"Biomedical Advanced Research and Development Authority","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Agreement","leadProduct":"Brincidofovir","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Approved","graph3":"Chimerix","amount2":0.37,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Infectious Diseases","amount2New":0.37,"dosageForm":"Tablet","sponsorNew":"Chimerix \/ Biomedical Advanced Research and Development Authority","highestDevelopmentStatusID":"12","companyTruncated":"Chimerix \/ Biomedical Advanced Research and Development Authority"},{"orgOrder":0,"company":"Emergent BioSolutions","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Brincidofovir","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Emergent BioSolutions","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Emergent BioSolutions \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Emergent BioSolutions \/ Not Applicable"}]

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                            01

                            Emergent BioSolutions

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                            Emergent BioSolutions

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Emergent BioSolutions Tests Brincidofovir for Mpox Virus Safety and Efficacy in Africa

                            Details : Tembexa (brincidofovir) is an antiviral medical countermeasure that is part of Emergent’s product portfolio and will be evaluated for the safety and efficacy in treating mpox virus.

                            Brand Name : Tembexa

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 06, 2024

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Chimerix

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Biomedical Advanced Research and Development Authority

                            Deal Size : $374.5 million

                            Deal Type : Agreement

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                            Chimerix Awarded BARDA Contract for TEMBEXA as Medical Countermeasure for Smallpox

                            Details : Collaboration with BARDA for the development of TEMBEXA (brincidofovir) has provided the United States government with a second therapeutic option to ensure the federal government’s readiness for a potential smallpox emergency.

                            Brand Name : Tembexa

                            Molecule Type : Small molecule

                            Upfront Cash : $238.0 million

                            August 29, 2022

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Biomedical Advanced Research and Development Authority

                            Deal Size : $374.5 million

                            Deal Type : Agreement

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                            03

                            Chimerix

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Public Health Agency of Canada

                            Deal Size : $25.3 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Chimerix Announces TEMBEXA Procurement Agreement for Approximately $25.3 Million with Public Health Agency of ...

                            Details : Chimerix signed a contract agreement to procure TEMBEXA® (brincidofovir). Execution of this contract will be the responsibility of Chimerix, as it is expected to substantially occur prior to the close of the pending transaction with Emergent BioSolution...

                            Brand Name : Tembexa

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 24, 2022

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Public Health Agency of Canada

                            Deal Size : $25.3 million

                            Deal Type : Agreement

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                            04

                            Chimerix

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Emergent BioSolutions

                            Deal Size : $9.3 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Chimerix Announces $9.3 Million International TEMBEXA Procurement Agreement

                            Details : Chimerix expects to promptly provide treatment courses of TEMBEXA (brincidofovir) equivalent to the total value of the procurement contract. Execution of this contract will be the responsibility of Chimerix.

                            Brand Name : Tembexa

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 23, 2022

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Emergent BioSolutions

                            Deal Size : $9.3 million

                            Deal Type : Agreement

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                            05

                            Chimerix

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Emergent BioSolutions

                            Deal Size : $325.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Emergent BioSolutions to Acquire from Chimerix its Exclusive Worldwide Rights to TEMBEXA® (brincidofovir), th...

                            Details : TEMBEXA (brincidofovir), is an oral antiviral formulated as 100 mg tablets and 10 mg/mL oral suspension dosed once weekly for two weeks. TEMBEXA is indicated for the treatment of human smallpox disease in adult and pediatric patients, including neonates.

                            Brand Name : Tembexa

                            Molecule Type : Small molecule

                            Upfront Cash : $225.0 million

                            May 16, 2022

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Emergent BioSolutions

                            Deal Size : $325.0 million

                            Deal Type : Acquisition

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                            06

                            Chimerix

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                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Chimerix Presents Data Supporting Brincidofovir as a Potential Treatment for Smallpox at 2020 American Society...

                            Details : Brincidofovir demonstrated a statistically significant survival advantage in two well-characterized animal models of lethal orthopoxvirus infection.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 29, 2020

                            Lead Product(s) : Brincidofovir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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