[{"orgOrder":0,"company":"Oruka Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bucindolol Hydrochloride","moa":"Adrenergic beta-1 receptor","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Oruka Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Oruka Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Oruka Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Oruka Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Bucindolol Hydrochloride","moa":"Beta","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase II","graph3":"Oruka Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Oruka Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Oruka Therapeutics \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals for Bucindolol Hydrochloride

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01

ISPE Aseptic Conference
Not Confirmed
ISPE Aseptic Conference
Not Confirmed

Details : In a GENETIC-AF Phase 2b clinical trial, the prevalence of bradycardia was significantly lower for Gencaro compared to metoprolol. Gencaro, is an investigational, pharmacologically unique beta-blocker for the treatment of atrial fibrillation in heart fai...

Product Name : Gencaro

Product Type : Small molecule

Upfront Cash : Not Applicable

January 04, 2022

Lead Product(s) : Bucindolol Hydrochloride

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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02

ISPE Aseptic Conference
Not Confirmed
ISPE Aseptic Conference
Not Confirmed

Details : New data provide additional evidence of efficacy for Gencaro compared to active control in a pharmacogenetically-defined HF population at risk for AF recurrence.

Product Name : Undisclosed

Product Type : Small molecule

Upfront Cash : Not Applicable

May 07, 2020

Lead Product(s) : Bucindolol Hydrochloride

Therapeutic Area : Cardiology/Vascular Diseases

Highest Development Status : Phase II

Sponsor : Not Applicable

Deal Size : Not Applicable

Deal Type : Not Applicable

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