Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : C4X_3256
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Indivior
Deal Size : $20.4 million
Deal Type : Divestment
C4X Discovery Holdings PLC Announces Divestment of Orexin-1 to Indivior for £15.95m
Details : Through the divestment, Indivior gains the proprietary rights to C4XD’s oral Orexin-1 receptor antagonist, INDV-2000 (C4X_3256) for substance use disorder.
Brand Name : INDV-2000
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 01, 2023
Lead Product(s) : C4X_3256
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Indivior
Deal Size : $20.4 million
Deal Type : Divestment
Lead Product(s) : C4X_6665
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Preclinical
Sponsor : AstraZeneca
Deal Size : $402.0 million
Deal Type : Agreement
C4XD Agreement with AstraZeneca
Details : C4XD signs licence agreement with AstraZeneca for the development and commercialisation of NRF2 Activator programme. NRF2 is an important natural regulator, controlling the expression of antioxidant genes, and it plays a key role in cellular defense agai...
Brand Name : C4X_6665
Molecule Type : Small molecule
Upfront Cash : $2.0 million
November 28, 2022
Lead Product(s) : C4X_6665
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Preclinical
Sponsor : AstraZeneca
Deal Size : $402.0 million
Deal Type : Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Study Phase : Preclinical
Sponsor : Sanofi
Deal Size : $433.2 million
Deal Type : Licensing Agreement
Details : Under the license, Sanofi will develop and commercialise an oral therapy for the treatment of inflammatory diseases. The IL-17 family of cytokines are inducers of inflammation in variety of autoimmune diseases including psoriasis, psoriatic arthritis & a...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $7.3 million
April 12, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Highest Development Status : Preclinical
Sponsor : Sanofi
Deal Size : $433.2 million
Deal Type : Licensing Agreement
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