Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : AstraZeneca
Deal Size : $350.0 million
Deal Type : Acquisition
Fortress Biotech Announces Closing of Acquisition of Caelum Biosciences by AstraZeneca
Details : Caelum was acquired by AstraZeneca pursuant to the developing and commercializing biopharmaceutical products and product candidates cost-effectively including Caelum’s lead asset, CAEL-101, is a novel antibody for the treatment of patients with light c...
Brand Name : CAEL-101
Molecule Type : Large molecule
Upfront Cash : $150.0 million
October 06, 2021
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : AstraZeneca
Deal Size : $350.0 million
Deal Type : Acquisition
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : AstraZeneca
Deal Size : $500.0 million
Deal Type : Acquisition
Astra Zeneca to Fully Acquire Caelum Biosciences
Details : AstraZeneca will accelerate ongoing Phase III clinical development of CAEL-101, a potential first-in-class medicine which is being evaluated in the Cardiac Amyloid Reaching for Extended Survival Phase III clinical programme in combination with standard-o...
Brand Name : CAEL-101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 29, 2021
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : AstraZeneca
Deal Size : $500.0 million
Deal Type : Acquisition
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : An e-poster featuring the first data from a new arm of the study demonstrated that CAEL-101 administered in combination with cyclophosphamide-bortezomib-dexamethasone (CyBorD) plus daratumumab was generally safe and well-tolerated in the first four weeks...
Brand Name : CAEL-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 11, 2021
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Accepted abstracts include Phase 2 safety, efficacy, and tolerability data for CAEL-101 in AL amyloidosis. Data, from Caelum, that further shows safety and tolerability of CAEL-101 and support the selection of the 1000 mg/m2 dose for the Phase 3 study wi...
Brand Name : CAEL-101
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 04, 2020
Lead Product(s) : CAEL-101,Cyclophosphamide,Bortezomib
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Alexion Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
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