Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LEO Pharma Submits NDA For Enstilar® For Psoriasis Treatment in China
Details : Enstilar is a combination of calcipotriene hydrate as a synthetic vitamin D3 analog and betamethasone dipropionate as a synthetic corticosteroid, indicated as topical treatment of plaque psoriasis.
Brand Name : Enstilar
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 27, 2024
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Hyphens Pharma
Deal Size : $2.7 million
Deal Type : Licensing Agreement
Hyphens Pharma licenses Wynzora® Cream for ASEAN countries from MC2 Therapeutics
Details : MC2 gains commercialization rights for Wynzora, an approved product indicated for treating plaque psoriasis in patients 18 years and older, through a license agreement.
Brand Name : Wynzora
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 12, 2024
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Hyphens Pharma
Deal Size : $2.7 million
Deal Type : Licensing Agreement
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The product is the combination of calcipotriene hydrate as a synthetic vitamin D3 analog and betamethasone dipropionate as a synthetic corticosteroid. It is indicated for the topical treatment of plaque psoriasis.
Brand Name : Enstilar-Generic
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 23, 2023
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : MC2 Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : WYNZORA is a cream-based fixed dose combination of calcipotriene and betamethasone dipropionate for topical treatment of plaque psoriasis. It is based on PAD™ Technology, which enables stability of both calcipotriene and betamethasone dipropionate in a...
Brand Name : Wynzora
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 15, 2022
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : MC2 Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Betamethasone
Therapeutic Area : Dermatology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Positive results from the Phase III study with Lipidor’s drug candidate AKP02, which is based on calcipotriol alone & in combination with betamethasone, show that AKVANO® technology works well for drugs for treatment of psoriasis.
Brand Name : AKP02
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 20, 2022
Lead Product(s) : Calcipotriol,Betamethasone
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Beclomethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Phase III
Sponsor : Menarini
Deal Size : $83.1 million
Deal Type : Licensing Agreement
Details : Under the terms of this agreement, RELIFE S.r.l shall register, promote, distribute and market Lipidor's calcipotriol based drug candidates for the treatment of psoriasis in EU, Turkey, UK, Switzerland, CIS, and Balkan countries.
Brand Name : AKP01
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 01, 2021
Lead Product(s) : Calcipotriol,Beclomethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Sponsor : Menarini
Deal Size : $83.1 million
Deal Type : Licensing Agreement
Lead Product(s) : Calcipotriol,Betamethasone
Therapeutic Area : Dermatology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AKP02 is a drug candidate for psoriasis that combines calcipotriol and betamethasone and is based on Lipidor’s patented AKVANO® technology.
Brand Name : AKP02
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 22, 2021
Lead Product(s) : Calcipotriol,Betamethasone
Therapeutic Area : Dermatology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Almirall
Deal Size : Undisclosed
Deal Type : Collaboration
Details : In this collaboration Almirall will commercialize Wynzora® Cream for treatment of plaque psoriasis in Europe and MC2 Therapeutics will be responsible for manufacturing and supply.
Brand Name : Wynzora
Molecule Type : Small molecule
Upfront Cash : $18.0 million
February 17, 2021
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Almirall
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : U.S. Prescribing Information (USPI) updated to include PSO-LONG clinical trial data concerning long-term use (52 weeks) of twice-weekly topical treatment with Enstilar® (calcipotriene and betamethasone dipropionate) Foam in adults with plaque psoriasis.
Brand Name : Enstilar
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 22, 2020
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Study Phase : Approved
Sponsor : MC2 Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Collaboration accelerates a Q1 2021 comprehensive launch of MC2’s WYNZORA® Cream to patients with plaque psoriasis in the US. WYNZORA® Cream is the first drug based on PADTM Technology – providing innovative solutions to unmet needs in chronic infl...
Brand Name : Wynzora
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 24, 2020
Lead Product(s) : Calcipotriol,Betamethasone Dipropionate
Therapeutic Area : Dermatology
Highest Development Status : Approved
Sponsor : MC2 Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
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