[{"orgOrder":0,"company":"Calico Life Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Fosigotifator","moa":"eIF2B","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Calico Life Sciences","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral","sponsorNew":"Calico Life Sciences \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Calico Life Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Calico Life Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Fosigotifator","moa":"eIF2B","graph1":"Genetic Disease","graph2":"Phase I\/ Phase II","graph3":"Calico Life Sciences","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral","sponsorNew":"Calico Life Sciences \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Calico Life Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Calico Life Sciences","sponsor":"AbbVie Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Collaboration","leadProduct":"ABBV-CLS-579","moa":"PTPN2","graph1":"Oncology","graph2":"Phase I","graph3":"Calico Life Sciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Calico Life Sciences \/ AbbVie Inc","highestDevelopmentStatusID":"6","companyTruncated":"Calico Life Sciences \/ AbbVie Inc"}]

Find Clinical Drug Pipeline Developments & Deals by Calico Life Sciences

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                          01

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : ABBV-CLS-7262 (fosigotifator) is an eIF2B activator, a factor that is essential for protein synthesis and a key regulator of the ISR. It is being investigated for vanishing white matter disease.

                          Product Name : ABBV-CLS-7262

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 06, 2024

                          Lead Product(s) : Fosigotifator

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : ABBV-CLS-7262 is an eIF2B activator which targets eIF2B, a guanine nucleotide exchange factor that is essential for protein synthesis and a key regulator of the ISR. It is being investigated for vanishing white matter disease.

                          Product Name : ABBV-CLS-7262

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          April 26, 2023

                          Lead Product(s) : Fosigotifator

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          MAGHREB PHARMA
                          Not Confirmed
                          MAGHREB PHARMA
                          Not Confirmed

                          Details : ABBV 579 is an IO asset, it is being studied in participants with locally advanced or metastatic tumors. As part of the collaboration, Calico pursues discovery-stage research and development utilizing state-of-the-art technology and advanced computing ca...

                          Product Name : ABBV 579

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          July 27, 2021

                          Lead Product(s) : ABBV-CLS-579

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : AbbVie Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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