Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : J.P. Morgan
Deal Size : $75.0 million
Deal Type : Public Offering
CAMP4 Announces Pricing of Initial Public Offering
Details : The proceeds will advance the development of CMP-CPS-001, designed to upregulate CPS1 gene expression by binding to a CPS1-specific regulatory RNA sequence, for the treatment of Urea cycle disorders.
Brand Name : CMP-CPS-001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 10, 2024
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : J.P. Morgan
Deal Size : $75.0 million
Deal Type : Public Offering
Lead Product(s) : regRNA-based Therapy
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Discovery Platform
Sponsor : BioMarin Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
CAMP4 Partners on Research to Develop RNA-Targeting Medicines for Rare Diseases
Details : The collaboration combines BioMarin’s expertise in drug development with CAMP4’s platform-based target discovery capabilities to advance novel regRNA-targeting medicines for rare genetic conditions.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 01, 2024
Lead Product(s) : regRNA-based Therapy
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Discovery Platform
Sponsor : BioMarin Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CAMP4 Secures Orphan Drug Status For CMP-CPS-001 in Urea Cycle Disorders
Details : CMP-CPS-001 is an ASO designed to amplify CPS1 mRNA by harnessing fundamental cellular gene expression control mechanisms. It is being evaluated for the treatment of urea cycle disorders.
Brand Name : CMP-CPS-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 17, 2024
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CAMP4 Wins Rare Pediatric Disease Designation for Urea Cycle Disorder Treatment
Details : CMP-CPS-001 is an ASO designed to amplify CPS1 mRNA by harnessing fundamental cellular gene expression control mechanisms. It is being evaluated for the treatment of urea cycle disorders.
Brand Name : CMP-CPS-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 27, 2024
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CAMP4 Doses First Participant in Phase 1 Study of CMP-CPS-001 for Urea Cycle Disorders
Details : CMP-CPS-001 is an antisense oligonucleotide (ASO) designed to amplify CPS1 mRNA by harnessing fundamental cellular gene expression control mechanisms. It is being evaluated for urea cycle disorders.
Brand Name : CMP-CPS-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 21, 2024
Lead Product(s) : CMP-CPS-001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Discovery
Sponsor : Fulcrum Therapeutics
Deal Size : $70.0 million
Deal Type : Licensing Agreement
Fulcrum Therapeutics Signs Exclusive Global License Agreement in Rare Hematology
Details : Fulcrum gains worldwide license to intellectual property arising from CAMP4’s DBA program, including the rights for discovery, development, and commercialization of novel therapeutic agents against an undisclosed target for the potential treatment of D...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 10, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Discovery
Sponsor : Fulcrum Therapeutics
Deal Size : $70.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Antisense Oligonucleotide Therapeutic
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Patient Square Capital
Deal Size : $100.0 million
Deal Type : Series B Financing
Details : The financing round will further support the advancement of CAMP4’s drug candidates, including progressing its urea cycle disorder program into the clinic and continuing to build an expansive pipeline of RNA actuators.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 20, 2022
Lead Product(s) : Antisense Oligonucleotide Therapeutic
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Patient Square Capital
Deal Size : $100.0 million
Deal Type : Series B Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : OPKO Health
Deal Size : $93.5 million
Deal Type : Licensing Agreement
OPKO Health Licenses Oligonucleotide Therapeutics Platform to CAMP4 Therapeutics
Details : CAMP4 is pioneering a novel approach to programmable therapeutics that combines a deep understanding of regulatory RNA and gene expression with a complementary and customizable oligonucleotide modality.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 12, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : OPKO Health
Deal Size : $93.5 million
Deal Type : Licensing Agreement
Lead Product(s) : regRNAs Therapies
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : 5AM Ventures
Deal Size : $45.0 million
Deal Type : Financing
CAMP4 Raises $45 Million to Usher in a New Era of Programmable Therapeutics to Upregulate Genes
Details : Proceeds to fuel expansion of RNA Actuating Platform™ designed to harness the power of regulatory RNA to restore healthy gene expression. Company advancing preclinical pipeline initially focused on CNS and liver diseases; first IND expected in 2022.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 15, 2021
Lead Product(s) : regRNAs Therapies
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : 5AM Ventures
Deal Size : $45.0 million
Deal Type : Financing
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