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Find Clinical Drug Pipeline Developments & Deals by Cancer Prevention Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Flynpovi is a combination of CPP-1X (eflornithine) and sulindac with a dual mechanism inhibiting polyamine synthesis and increase polyamine export and catabolism. The safety profile for Flynpovi did not differ from the single agents and supports the eval...

                          Brand Name : Flynpovi

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 16, 2022

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Panbela Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The combined entity will have an expanded pipeline addressing focus: familial adenomatous polyposis (FAP), first-line metastatic pancreatic cancer, neoadjuvant pancreatic cancer, colorectal cancer prevention and ovarian cancer, including Flynpovi, the le...

                          Brand Name : Flynpovi

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 22, 2022

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Panbela Therapeutics

                          Deal Size : $60.0 million

                          Deal Type : Acquisition

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Although the trial did not demonstrate that overall disease progression was significantly lower with CPP-1X/sul compared to eflornithine or sulindac alone, in a subgroup of patients with intact colons there was a 70% decreased risk of disease progression...

                          Brand Name : CPP-1X/sul

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 11, 2020

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The clinical development of CPP-1X/sul was designed to establish this fixed dose combination product as a potential pharmaco-preventive drug treatment specifically for FAP patients.

                          Brand Name : CPP-1X/sul

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 29, 2020

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Cancer Prevention Pharmaceuticals plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration this month seeking accelerated approval for CPP-IX/sul for the same indication.

                          Brand Name : CPP-1X/sul

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 18, 2020

                          Lead Product(s) : Eflornithine Hydrochloride,Sulindac

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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