[{"orgOrder":0,"company":"Cancer Targeted Technology","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Funding","leadProduct":"CTT1403","moa":"PSMA","graph1":"Oncology","graph2":"Phase I","graph3":"Cancer Targeted Technology","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Cancer Targeted Technology \/ National Institute of Health","highestDevelopmentStatusID":"6","companyTruncated":"Cancer Targeted Technology \/ National Institute of Health"},{"orgOrder":0,"company":"Cancer Targeted Technology","sponsor":"National Cancer Institute","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Funding","leadProduct":"CTT2274","moa":"","graph1":"Technology","graph2":"Approved","graph3":"Cancer Targeted Technology","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"Cancer Targeted Technology \/ National Cancer Institute","highestDevelopmentStatusID":"12","companyTruncated":"Cancer Targeted Technology \/ National Cancer Institute"}]

Find Clinical Drug Pipeline Developments & Deals by Cancer Targeted Technology

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The funding will be used to develop a new prodrug, CTT2274, that targets PSMA on prostate cancer and is designed to release a toxic drug, MMAE, within the cell that takes up the prodrug.

                          Brand Name : CTT2274

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : CTT2274

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : National Cancer Institute

                          Deal Size : $2.4 million

                          Deal Type : Funding

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The trial is designed to show safety and efficacy of CTT1403 and is halfway through the initial dose escalation phase. CTT1403 targets Prostate Specific Membrane Antigen (PSMA) which is over-expressed on prostate cancer.

                          Brand Name : CTT1403

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 07, 2020

                          Lead Product(s) : CTT1403

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : National Institutes of Health

                          Deal Size : $1.4 million

                          Deal Type : Funding

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