Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Reports Positive Data from Phase 2 Trial of CAN-2409 in Pancreatic Cancer
Details : CAN-2409 (aglatimagene besadenovec) a gene therapy which constructs encoding for thymidine kinase gene. It is being evaluated with valacyclovir for borderline resectable pancreatic adenocarcinoma.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 03, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Grants ODD for CAN-3110 for the Treatment of Recurrent High-Grade Glioma
Details : CAN-3110 is a first-in-class, replication-competent HSV-1 oncolytic viral immunotherapy candidate for the treatment of patients with recurrent high-grade glioma to improve overall survival.
Brand Name : CAN-3110
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 30, 2024
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Receives FDA Orphan Drug Designation for CAN-2409 in Pancreatic Cancer
Details : CAN-2409 is an investigational replication-defective adenovirus delivering the HSV-tk gene, combined with valacyclovir, being studied for pancreatic cancer treatment.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 11, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Therapeutics Announces Positive Interim Data from Phase 2 Trial Of Can-2409
Details : CAN-2409 (aglatimagene besadenovec) is an adenoviral replication-defective engineered gene, evaluated with valacyclovir for borderline resectable pancreatic cancer.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 04, 2024
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Batavia Bioscience
Deal Size : Undisclosed
Deal Type : Partnership
Batavia and Candel Partner to Accelerate Development of CAN-3110
Details : The partnership aims to accelerate the development and production of CAN-3110, an oncolytic viral immunotherapy for glioma brain tumors, based on a replication attenuated Herpes Simplex Virus (HSV).
Brand Name : CAN-3110
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 21, 2024
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Batavia Bioscience
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CAN-3110 Receives FDA Fast Track Designation for Treatment of Recurrent High-Grade Glioma
Details : CAN-3110 is an oncolytic viral immunotherapy based on HSV-1, developed for recurrent high-grade glioma to improve overall survival.
Brand Name : CAN-3110
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 13, 2024
Lead Product(s) : CAN-3110,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Therapeutics Receives FDA Fast Track Designation for CAN-2409 in Pancreatic Cancer
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 12, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells.
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 03, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells. It has received fast track designation for NSCLC in combinati...
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 26, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Candel Therapeutics Receives FDA Fast Track Designation for CAN-2409 in Non-Small Cell Lung Cancer
Details : CAN-2409 (aglatimagene besadenovec) plus valacyclovir is a replication-defective adenovirus that is designed to deliver the herpes simplex virus thymidine kinase (HSV-tk) gene to cancer cells. It has received fast track designation for NSCLC in combinati...
Brand Name : CAN-2409
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 17, 2023
Lead Product(s) : Aglatimagene Besadenovec,Valacyclovir
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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