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    Capivasertib

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    01

    AstraZeneca

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    Lead Product(s) : Capivasertib,Abiraterone Acetate,Prednisone

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    TRUQAP® (capivasertib) Phase 3 Shows Radiographic PFS Benefit in Prostate Cancer

    Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor, is being investigated for PTEN-deficient de novo mHSPC in combination with abiraterone and ADT.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    November 25, 2024

    Lead Product(s) : Capivasertib,Abiraterone Acetate,Prednisone

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    02

    AstraZeneca

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    AstraZeneca

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    Lead Product(s) : Capivasertib,Paclitaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    CAPItello-290 Phase III: Truqap Plus Chemo in Advanced Triple-Negative Breast Cancer

    Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor of AKT1/2/3. It is being evaluated for the treatment of locally advanced or metastatic triple-negative breast cancer.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    June 18, 2024

    Lead Product(s) : Capivasertib,Paclitaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    03

    AstraZeneca

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    AstraZeneca

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Truqap Plus Faslodex Recommended for EU Approval in Advanced ER-positive Breast Cancer

    Details : Truqap (capivasertib) is a first-in-class AKT inhibitor approved in combination with fulvestrant for advanced HR-positive breast cancer treatment.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    April 29, 2024

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    04

    AstraZeneca

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    AstraZeneca

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Truqap Plus Faslodex Approved in Japan for Advanced HR-Positive Breast Cancer

    Details : Truqap (capivasertib) is an ATP-competitive inhibitor of all AKT isoforms, approved in combination with Faslodex (fulvestrant) for advanced HR-positive breast cancer treatment.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    March 27, 2024

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    05

    Chugai Pharmaceutical

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    Chugai Pharmaceutical

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Chugai Obtains Approval for FoundationOne CDx as Diagnostic for Capivasertib in BC

    Details : Truqap (capivasertib) is a first-in-class ATP-competitive inhibitor of all three AKT isoforms, approved with Faslodex (fulvestrant) for advanced HER2-/HR+ breast cancer treatment.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    March 27, 2024

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    06

    Astex Pharmaceuticals

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    Astex Pharmaceuticals

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : $275.0 million

    Deal Type : Collaboration

    DEALS_DEV arrow-down

    Otsuka's U.K. subsidiary Astex Has Third Approval Success in a Drug Discovery Collaboration - AstraZeneca's T...

    Details : Truqap, a first-in-class AKT inhibitor, discovered by AstraZeneca subsequent to its collaboration with Astex, recently approved by FDA in combination with Faslodex, for treatment for adult patients with HR-positive, HER2-negative, locally advanced or met...

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : $5.0 million

    November 22, 2023

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : $275.0 million

    Deal Type : Collaboration

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    07

    Astex Pharmaceuticals

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    Astex Pharmaceuticals

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : $275.0 million

    Deal Type : Collaboration

    DEALS_DEV arrow-down

    Third Success from Astex Drug Discovery Pharma Collaboration and Licence Agreements as AstraZeneca Receives US...

    Details : Truqap (capivasertib), a first in class, oral targeted inhibitor of the cancer-driving protein AKT, was discovered by AstraZeneca subsequent to its discovery collaboration with Astex.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : $5.0 million

    November 20, 2023

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : AstraZeneca

    Deal Size : $275.0 million

    Deal Type : Collaboration

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    08

    Foundation Medicine

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    Foundation Medicine

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    U.S. FDA Approves FoundationOne®CDx as a Companion Diagnostic for AstraZeneca’s Truqap™ (capivasertib) in...

    Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor of all three AKT isoforms (AKT1/2/3). It is approved in combination with fulvestrant for the treatment of patients with advanced HR-positive breast cancer.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    November 20, 2023

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    09

    AstraZeneca

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    TRUQAP™ (capivasertib) Plus Fulvestrant Approved in The Us for Patients with Advanced HR-Positive Breast Can...

    Details : Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor of all three AKT isoforms (AKT1/2/3). It is approved in combination with fulvestrant for the treatment of patients with advanced HR-positive breast cancer.

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    November 17, 2023

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    10

    AstraZeneca

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    AstraZeneca

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    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Capivasertib In Combination With Faslodex (Fulvestrant) Granted Priority Review In The Us For Patients With Ad...

    Details : AZD5363 (capivasertib) is an investigational orally and potent, adenosine triphosphate (ATP)-competitive inhibitor of all three AKT isoforms (AKT1/2/3) and in combination with Faslodex granted Priority Review in the US for patients with advanced HR-posit...

    Product Name : Truqap

    Product Type : Other Small Molecule

    Upfront Cash : Inapplicable

    June 12, 2023

    Lead Product(s) : Capivasertib,Fulvestrant

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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