Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $600.0 million
Deal Type : Partnership
NanoVation Partners with Novo Nordisk For Cardiometabolic And Rare Genetic Medicines
Details : Novo and NanoVation will be partnering for two lead programs to develop base-editing therapies for certain rare genetic diseases, and up to five additional future targets for cardiometabolic diseases.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 18, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $600.0 million
Deal Type : Partnership
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Collaboration
BenevolentAI Announces Further Success with AstraZeneca Collaboration
Details : Under the collaboration, a novel target for Heart Failure was discovered using BenevolentAI’s AI-drug discovery platform and experimentally validated by AstraZeneca.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
May 15, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : AstraZeneca
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $1,460.0 million
Deal Type : Collaboration
Neomorph Announces Collaboration with Novo Nordisk to Discover Molecular Glue Degraders
Details : The collaboration leverages Neomorph's leading molecular glue discovery platform and Novo Nordisk's extensive expertise in cardiometabolic and rare diseases.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
February 26, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $1,460.0 million
Deal Type : Collaboration
Lead Product(s) : RNA Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Bristol Myers Squibb
Deal Size : $2,275.0 million
Deal Type : Collaboration
Details : The collaboration aims to focus on discovery, development and commercialization of up to five cardiovascular targets by leveraging Avidity's proprietary AOC platform technology, to deliver a new class of RNA therapeutics called Antibody Oligonucleotide C...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $100.0 million
November 28, 2023
Lead Product(s) : RNA Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Bristol Myers Squibb
Deal Size : $2,275.0 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to accelerate the translation of academic ideas to therapeutic product candidates in the cardiometabolic space through LAB eN² that combines Evotec's multimodality drug discovery and preclinical development capabilities.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
September 26, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $2,760.0 million
Deal Type : Collaboration
Details : The collaboration will leverage Valo’s Opal Computational Platform including access to real-world patient data, AI-enabled small molecule discovery and Biowire® human tissue modelling platform to discover and develop novel treatments for cardiometabol...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 25, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Novo Nordisk
Deal Size : $2,760.0 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Newpath Partners
Deal Size : $50.0 million
Deal Type : Series A Financing
Details : The financing will support Magnet's approach to the discovery and development of TrueGlues™, compounds inducing cooperative protein-protein interactions and will advance its portfolio spanning several indications, including oncology, cardiovascular, an...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Newpath Partners
Deal Size : $50.0 million
Deal Type : Series A Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : InSyBio
Deal Size : Undisclosed
Deal Type : Partnership
Syndesis Health and InSyBio Partner in Predictive Modelling and Biomarker Discovery
Details : The partnership aims to leverage the clinical and genomic data on Syntium, Syndesis' data platform of global healthcare data, to accelerate research and development in several therapeutic areas, including cardiovascular health, oncology, and rare disease...
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
September 19, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : InSyBio
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Oligonucleotide Therapy
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : Ionis Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Scipher Medicine Signs Multi-Target Partnership with Ionis
Details : Under the collaboration, Ionis will be responsible for advancing, developing and commercializing oligonucleotide therapies directed to targets discovered by Scipher’s Spectra™ platform.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 17, 2023
Lead Product(s) : Oligonucleotide Therapy
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : Ionis Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : siRNA Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery Platform
Sponsor : AstraZeneca
Deal Size : $4,080.0 million
Deal Type : Collaboration
Silence Therapeutics Achieves $10 Million Milestone Payment from AstraZeneca Collaboration
Details : Under the agreement, Silence and AstraZeneca is focused on using Silence’s proprietary mRNAi GOLD™ platform to develop siRNA therapeutics for cardiovascular, renal, metabolic and respiratory diseases.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : $80.0 million
May 04, 2023
Lead Product(s) : siRNA Therapeutic
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery Platform
Sponsor : AstraZeneca
Deal Size : $4,080.0 million
Deal Type : Collaboration
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