Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Novo Nordisk
Deal Size : $1,110.0 million
Deal Type : Acquisition
Novo Nordisk to Acquire Cardior Pharmaceuticals, Enhancing Its Cardiovascular Pipeline
Details : Through the acquisition, Novo Nordisk expand its pipeline in cardiovascular disease by including Cardior’s lead compound CDR132L, currently in phase 2 clinical development for heart failure.
Brand Name : CDR132L
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 25, 2024
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Novo Nordisk
Deal Size : $1,110.0 million
Deal Type : Acquisition
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CDR132L is synthetic antisense oligonucleotide-based inhibitor directed against microRNA-132, that up-regulated in cardiac tissue of heart failure patients leading to expression of genes that are crucially involved in cardiac function thus leading to pat...
Brand Name : CDR132L
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 20, 2022
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Inkef Capital
Deal Size : $76.0 million
Deal Type : Series B Financing
Details : The Series B proceeds will be used to fund the late-stage clinical development of Cardior’s lead program, CDR132L and the expansion of the company’s earlier-stage pipeline.
Brand Name : CDR132L
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 25, 2021
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Inkef Capital
Deal Size : $76.0 million
Deal Type : Series B Financing
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The recent peer-reviewed study confirms the therapeutic mode of action of Cardior´s lead program CDR132L. CDR132L blocks the naturally occurring microRNA miR-132 which, if overexpressed, is a key driver of heart failure.
Brand Name : CDR132L
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 29, 2021
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The study demonstrates that repeated treatment with its lead compound Cdr132 L is safe, improves cardiac function and reduces both ventricular as well as left atrial volumes in chronic heart failure.
Brand Name : CDR132L
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 22, 2020
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Cardior Pharmaceuticals Demonstrates Reversal of Heart Failure with Lead Compound CDR132L
Details : In the in vivo study, Cardior´s compound CDR132L effectively prevented maladaptive growth and remodeling and restored cardiac function in a dose-dependent manner.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
January 31, 2020
Lead Product(s) : CDR132L
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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