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    [{"orgOrder":0,"company":"Santen Pharmaceutical","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"JAPAN","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Carotuximab","moa":"","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Santen Pharmaceutical","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Intravitreal Injection","sponsorNew":"Santen Pharmaceutical \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Santen Pharmaceutical \/ Not Applicable"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Carotuximab","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Kairos Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Kairos Pharma \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Kairos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Carotuximab","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Kairos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Kairos Pharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Kairos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"Boustead Securities, LLC","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Public Offering","leadProduct":"Carotuximab","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Kairos Pharma","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"","sponsorNew":"Kairos Pharma \/ Boustead Securities, LLC","highestDevelopmentStatusID":"8","companyTruncated":"Kairos Pharma \/ Boustead Securities, LLC"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"Boustead Securities, LLC","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Public Offering","leadProduct":"Carotuximab","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Kairos Pharma","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.01,"dosageForm":"","sponsorNew":"Kairos Pharma \/ Boustead Securities, LLC","highestDevelopmentStatusID":"8","companyTruncated":"Kairos Pharma \/ Boustead Securities, LLC"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"PreCheck Health Services","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2024","type":"Collaboration","leadProduct":"Carotuximab","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Kairos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Kairos Pharma \/ PreCheck Health Services","highestDevelopmentStatusID":"8","companyTruncated":"Kairos Pharma \/ PreCheck Health Services"},{"orgOrder":0,"company":"Kairos Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Carotuximab","moa":"||Endoglin","graph1":"Oncology","graph2":"Phase II","graph3":"Kairos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Kairos Pharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Kairos Pharma \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Carotuximab

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    Carotuximab

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                            01

                            Kairos Pharma

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                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Kairos Pharma Adds Huntsman Cancer Institute for Phase 2 ENV105 Clinical Trial

                            Details : ENV105 (carotuximab) is a endoglin inhibitor which is being evaluated in phase 2 clinical trials in combination with apalutamide for the treatment of castrate-resistant prostate cancer.

                            Product Name : ENV105

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 11, 2025

                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Kairos Pharma

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                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : PreCheck Health Services

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Kairos Partners with PreCheck To Develop Biomarkers For Cancer Drug Resistance

                            Details : The collaboration aims to advance the precision of therapy monitoring for Kairos clinical trials, and to advance cancer treatment by identifying patients who will benefit most from ENV105.

                            Product Name : ENV105

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            September 24, 2024

                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : PreCheck Health Services

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            03

                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Boustead Securities, LLC

                            Deal Size : $6.2 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kairos Pharma Closing of $6.2 Million Initial Public Offering

                            Details : The net proceeds from the offering to fund the company's lead product candidate, ENV105 (carotuximab), which is being evaluated in a mid-stage trial studies for the treatment of prostate cancer.

                            Product Name : ENV105

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            September 17, 2024

                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Boustead Securities, LLC

                            Deal Size : $6.2 million

                            Deal Type : Public Offering

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                            04

                            Kairos Pharma

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                            Organic Process R&D
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                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Boustead Securities, LLC

                            Deal Size : $6.2 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Kairos Pharma Prices $6.2 Million Initial Public Offering

                            Details : The net proceeds from the offering to fund the company's lead product candidate, ENV105 (carotuximab), which is being evaluated in a mid-stage trial studies for the treatment of prostate cancer.

                            Product Name : ENV105

                            Product Type : Large molecule

                            Upfront Cash : Undisclosed

                            September 16, 2024

                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Boustead Securities, LLC

                            Deal Size : $6.2 million

                            Deal Type : Public Offering

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                            05

                            Kairos Pharma

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                            Organic Process R&D
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                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kairos Doses First Patient in Phase 2 of ENV105 with Apalutamide for Prostate Cancer

                            Details : ENV105 (carotuximab) is a endoglin inhibitor which is being evaluated in phase 2 clinical trials in combination with apalutamide for the treatment of castrate-resistant prostate cancer.

                            Product Name : ENV105

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 30, 2024

                            Lead Product(s) : Carotuximab,Apalutamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Kairos Pharma

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                            Kairos Pharma

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                            Lead Product(s) : Carotuximab,Osimertinib Mesylate

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kairos Pharma Doses First Patients in Phase 1 of ENV105 with Osimertinib for Lung Cancer

                            Details : ENV105 (carotuximab) is a novel ENG inhibitor monoclonal antibody. It is currently being evaluated in phase 1 clinical trials in combination with osimertinib for non-small cell lung cancer.

                            Product Name : ENV105

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            January 16, 2024

                            Lead Product(s) : Carotuximab,Osimertinib Mesylate

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Santen Pharmaceutical

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                            Santen Pharmaceutical

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                            Lead Product(s) : Carotuximab

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Santen, Tracon discontinue development of eye drug after mid-stage trial failure

                            Details : The companies said DE-122, when combined with Lucentis, did not meet the trial's main goal of improving visual acuity in patients with wet AMD compared to those taking Lucentis alone.

                            Product Name : Undisclosed

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 10, 2020

                            Lead Product(s) : Carotuximab

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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