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Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Carrick Therapeutics

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                            01

                            Carrick Therapeutics

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                            Lead Product(s) : CT7439

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Treats First Patient in Phase 1 Trial of CT7439 (CDK12/13 Inhibitor)

                            Details : CT7439 is a best-in-class novel cyclin-dependent kinase 12/13 inhibitor, which is being evaluated for the treatment of multiple neoplasms.

                            Brand Name : CT7439

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 23, 2024

                            Lead Product(s) : CT7439

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

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                            Lead Product(s) : Samuraciclib,Vepdegestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Doses First Patient in Phase 1b/2 Trial of Samuraciclib in Breast Cancer

                            Details : CT7001 (samuraciclib) is a first-in-class oral CDK7 inhibitor evaluated with ARV-471 (vepdegestrant) for ER+, HER2- metastatic breast cancer treatment.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 14, 2024

                            Lead Product(s) : Samuraciclib,Vepdegestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces First Patient Dosed in Phase 2b Clinical Trial of Samuraciclib in Combination w...

                            Details : Samuraciclib (CT7001) - an oral CDK7 inhibitor in combination with Fulvestrant is being evaluated in phase 2 clinical trials for the treatment of HER2- advanced breast cancer.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 15, 2023

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Elacestrant Dihydrochloride

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces First Patient Dosed in Phase 2 Clinical Trial of Samuraciclib in Combination wi...

                            Details : CT7001 (samuraciclib) is an oral and first-in-class inhibitor of CDK7, and the Menarini Group's (Menarini) oral selective estrogen receptor degrader (SERD), elacestrant, in patients with CDK4/6i resistant HR+, HER2- metastatic breast cancer.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 18, 2023

                            Lead Product(s) : Samuraciclib,Elacestrant Dihydrochloride

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Carrick Therapeutics

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                            Lead Product(s) : CT7439

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces U.S. FDA Clearance of IND for CT7439, a First-In-Class Inhibitor of CDK12/13

                            Details : CT7439 is an inhibitor of CDK12/13 as well as a 'glue degrader' of Cyclin-K, which is the obligate co-factor for CDK12/13, giving both first-in-class and best-in-class potential treatment of advanced solid tumors, including breast, ovarian and Ewing's Sa...

                            Brand Name : CT7439

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 07, 2023

                            Lead Product(s) : CT7439

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Arvinas

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces Clinical Trial Collaboration with Arvinas and Pfizer to Evaluate Samuraciclib a...

                            Details : The collaboration aims to evaluate the novel combination of CT7001 (samuraciclib), an oral, first-in-class inhibitor of CDK7, and Arvinas’ ARV-471 (vepdegestrant), an investigational oral PROTAC® estrogen receptor protein degrader being developed in m...

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 06, 2023

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Arvinas

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            07

                            Carrick Therapeutics

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                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : ARCH Venture Partners

                            Deal Size : $25.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Closes Series C Financing

                            Details : The Company intends to use the proceeds to fund ongoing and planned CT7001 (samuraciclib) clinical trials, ongoing development of its CDK12/13 inhibitor / Cyclin-K glue-degrader, and for working capital and general corporate purposes.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 01, 2022

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : ARCH Venture Partners

                            Deal Size : $25.0 million

                            Deal Type : Series C Financing

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                            08

                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : $35.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces $35 Million Investment from Pfizer

                            Details : CT7001 (samuraciclib), an oral CDK7 inhibitor, is a promising therapeutic strategy in cancer, as CDK7 regulates transcription of cancer-causing genes and promotes uncontrolled cell cycle progression and resistance to anti-hormone therapy.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 01, 2022

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : $35.0 million

                            Deal Type : Financing

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                            09

                            Carrick Therapeutics

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                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Announces $35 Million Investment from Pfizer

                            Details : Under the terms of the agreement, Pfizer will provide global development capabilities and expertise to support Carrick’s Phase 2 study of CT-7001 (samuraciclib) in combination with fulvestrant for CDK4/6i-resistant HR+, HER2- advanced breast cancer.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 01, 2022

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Pfizer Inc

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            Carrick Therapeutics

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                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Carrick Therapeutics Presents Encouraging Clinical Data for Samuraciclib (CT7001) at the 2021 San Antonio Brea...

                            Details : Clinical data on samuraciclib (CT7001), an oral and first-in-class inhibitor of CDK7, regulates the transcription of cancer-causing genes,support its continued development in breast cancer.

                            Brand Name : CT7001

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 09, 2021

                            Lead Product(s) : Samuraciclib,Fulvestrant

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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