Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CASI Gets CTA Approval in China for CID-103 in Immune Thrombocytopenia
Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, which is currently being evaluated for the treatment of chronic immune thrombocytopenia in adults.
Brand Name : CID-103
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 24, 2024
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CASI Pharmaceuticals Plans IND Submission for CID-103 and Receives Acquisition Proposal
Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, being investigated for the treatment of antibody-mediated rejection ("AMR") in kidney transplant.
Brand Name : CID-103
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 26, 2024
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CASI Pharmaceuticals Receives FDA IND Clearance for CID-103 in Immune Thrombocytopenia
Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, which is currently being evaluated for the treatment of chronic immune thrombocytopenia in adults.
Brand Name : CID-103
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 15, 2024
Lead Product(s) : CID-103
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BI-1206,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : BioInvent
Deal Size : Not Applicable
Deal Type : Not Applicable
CASI Pharmaceuticals Reports Positive Interim Phase 1 Data for BI-1206 in China
Details : BI-1206 is a first-in-class fully human mAb that targets FcγRIIB. It is being evaluated in combination with rituximab in patients with Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma.
Brand Name : BI-1206
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 05, 2024
Lead Product(s) : BI-1206,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : BioInvent
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Pralatrexate
Therapeutic Area : Oncology
Study Phase : Approved
Recipient : Acrotech Biopharma
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The partnership aims for the manufacturing and advancement of iTolerance's Streptavidin-FasL (SA-FasL) fusion protein, a crucial component of the proprietary iTOL-100 platform technology towards first in human clinical study for lead program, iTOL-102.
Brand Name : Folotyn
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 01, 2023
Lead Product(s) : Pralatrexate
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Acrotech Biopharma
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : CB-5339
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Cleave Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Through the acquisition, CASI gains global rights to the Cleave's clinical asset, CB-5339 tosylate, an oral, second-generation, small molecule valosin-containing protein (VCP)/p97 inhibitor, in patients with acute myeloid leukemia and myelodysplastic syn...
Brand Name : CB-5339
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 20, 2023
Lead Product(s) : CB-5339
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Cleave Therapeutics
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : CB-5339
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Cleave Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CB-5339 is an oral second-generation, small molecule VCP/p97 inhibitor, and is currently in Phase 1 clinical trial in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and myeloproliferative neoplasms.
Brand Name : CB-5339
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 06, 2023
Lead Product(s) : CB-5339
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Cleave Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Inaticabtagene Autoleucel,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CNCT19 (Inaticabtagene Autoleucel), is the first CAR-T cell therapy for the treatment of B-ALL submitted for NDA and has the potential to be the first approved domestic developed CD19 directed CAR-T therapy in China.
Brand Name : CNCT19
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 15, 2022
Lead Product(s) : Inaticabtagene Autoleucel,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BI1206,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : BioInvent
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BI-1206, a first-in-class fully human monoclonal antibody (mAb) that targets FcγRIIB, in combination with rituximab in patients with relapsed/refractory Non-Hodgkin's Lymphoma (NHL).
Brand Name : BI1206
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 07, 2022
Lead Product(s) : BI1206,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : BioInvent
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Under the terms of the agreement, CASI maintains exclusive US commercialization and co-marketing rights of CID-103 for the treatment, prevention, and diagnosis of autoimmune diseases, conditions, and disorders in the United States.
Brand Name : CID-103
Molecule Type : Large molecule
Upfront Cash : Undisclosed
July 08, 2022
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