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Find Clinical Drug Pipeline Developments & Deals by CASI Pharmaceuticals

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, which is currently being evaluated for the treatment of chronic immune thrombocytopenia in adults.

                          Brand Name : CID-103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 24, 2024

                          Lead Product(s) : CID-103

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, being investigated for the treatment of antibody-mediated rejection ("AMR") in kidney transplant.

                          Brand Name : CID-103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 26, 2024

                          Lead Product(s) : CID-103

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, which is currently being evaluated for the treatment of chronic immune thrombocytopenia in adults.

                          Brand Name : CID-103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 15, 2024

                          Lead Product(s) : CID-103

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : BI-1206 is a first-in-class fully human mAb that targets FcγRIIB. It is being evaluated in combination with rituximab in patients with Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma.

                          Brand Name : BI-1206

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 05, 2024

                          Lead Product(s) : BI-1206,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : BioInvent

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The partnership aims for the manufacturing and advancement of iTolerance's Streptavidin-FasL (SA-FasL) fusion protein, a crucial component of the proprietary iTOL-100 platform technology towards first in human clinical study for lead program, iTOL-102.

                          Brand Name : Folotyn

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 01, 2023

                          Lead Product(s) : Pralatrexate

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Recipient : Acrotech Biopharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through the acquisition, CASI gains global rights to the Cleave's clinical asset, CB-5339 tosylate, an oral, second-generation, small molecule valosin-containing protein (VCP)/p97 inhibitor, in patients with acute myeloid leukemia and myelodysplastic syn...

                          Brand Name : CB-5339

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 20, 2023

                          Lead Product(s) : CB-5339

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Cleave Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CB-5339 is an oral second-generation, small molecule VCP/p97 inhibitor, and is currently in Phase 1 clinical trial in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and myeloproliferative neoplasms.

                          Brand Name : CB-5339

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 06, 2023

                          Lead Product(s) : CB-5339

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Cleave Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : CNCT19 (Inaticabtagene Autoleucel), is the first CAR-T cell therapy for the treatment of B-ALL submitted for NDA and has the potential to be the first approved domestic developed CD19 directed CAR-T therapy in China.

                          Brand Name : CNCT19

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 15, 2022

                          Lead Product(s) : Inaticabtagene Autoleucel,Fludarabine Phosphate,Cyclophosphamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : BI-1206, a first-in-class fully human monoclonal antibody (mAb) that targets FcγRIIB, in combination with rituximab in patients with relapsed/refractory Non-Hodgkin's Lymphoma (NHL).

                          Brand Name : BI1206

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 07, 2022

                          Lead Product(s) : BI1206,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : BioInvent

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Under the terms of the agreement, CASI maintains exclusive US commercialization and co-marketing rights of CID-103 for the treatment, prevention, and diagnosis of autoimmune diseases, conditions, and disorders in the United States.

                          Brand Name : CID-103

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          July 08, 2022

                          Lead Product(s) : CID-103

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Precision Autoimmune Therapeutics

                          Deal Size : $21.0 million

                          Deal Type : Financing

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