Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Catabasis Pharmaceuticals To Present At Ladenburg Thalmann 2021 Healthcare Conference
Details : The lead program, QLS-215, is a monoclonal antibody inhibitor of plasma kallikrein in preclinical development for the treatment of hereditary angioedema.
Brand Name : QLS-215
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 07, 2021
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Study Phase : Preclinical
Recipient : Quellis Biosciences Inc
Deal Size : Undisclosed
Deal Type : Acquisition
Catabasis Pharmaceuticals Announces Acquisition Of Quellis Biosciences Inc.
Details : Acquisition Includes QLS-215, a Potential Best-in-Class Monoclonal Antibody Inhibitor of Plasma Kallikrein in Preclinical Development for the Treatment of Hereditary Angioedema.
Brand Name : QLS-215
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 29, 2021
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Highest Development Status : Preclinical
Recipient : Quellis Biosciences Inc
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $110.0 million
Deal Type : Private Placement
Catabasis Pharmaceuticals Announces Acquisition of Quellis Biosciences Inc.
Details : Through the acquisition, Catabasis strengthens its pipeline by including QLS-215, a Potential Best-in-Class Monoclonal Antibody Inhibitor of Plasma Kallikrein in Preclinical Development for the Treatment of Hereditary Angioedema.
Brand Name : QLS-215
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 29, 2021
Lead Product(s) : QLS-215
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Perceptive Advisors
Deal Size : $110.0 million
Deal Type : Private Placement
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Phase 3 PolarisDMD trial of edasalonexent in Duchenne muscular dystrophy (DMD) did not meet the primary endpoint, which was a change from baseline in the North Star Ambulatory Assessment (NSAA) over one year of edasalonexent compared to placebo.
Brand Name : CAT-1004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 26, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The posters include new preclinical research findings supporting potential positive effects on cardiac function and preservation of bone health with edasalonexent in mouse models of DMD.
Brand Name : CAT-1004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 28, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CAT-5571
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Bill & Melinda Gates Medical Research Institute
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreements aims at assessing CAT-5571 as a potential oral therapy to promote autophagy and clear persistent lung infections in patients with both drug-sensitive and drug-resistant tuberculosis (TB).
Brand Name : CAT-5571
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 04, 2020
Lead Product(s) : CAT-5571
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Bill & Melinda Gates Medical Research Institute
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Catabasis Pharmaceuticals to Present at Parent Project Muscular Dystrophy Virtual Annual Conference
Details : Catabasis Pharmaceuticals will present information on the edasalonexent program in Phase 3 development for the treatment of Duchenne muscular dystrophy (DMD) at the Parent Project Muscular Dystrophy (PPMD) Virtual Annual Conference.
Brand Name : CAT-1004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 15, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The posters provide an overview of the baseline status of patients involved in PolarisDMD Ph 3 trial, findings from the MoveDMD Ph 2 trial and effect of oral edasalonexent in both the clinical trials.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 12, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Catabasis Pharmaceuticals to Present at 2020 Muscular Dystrophy Association Virtual Poster Session
Details : Catabasis Pharmaceuticals to present information on the edasalonexent program in Phase 3 development for the treatment of Duchenne muscular dystrophy (DMD).
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 17, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Edasalonexent, an NF-kB inhibitor in Phase 3 development for the treatment of Duchenne muscular dystrophy, is the company's lead program.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 20, 2020
Lead Product(s) : Edasalonexent
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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