Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CDR813
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDR-Life Announces Pipeline Expansion of Highly Tumor-Targeted T Cell Engagers
Details : CDR813 is a highly potent and selective TCE candidate targeting tumors expressing PRAME (preferentially expressed antigen in melanoma) in HLA-A*02:01 patients.
Brand Name : CDR813
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 25, 2024
Lead Product(s) : CDR813
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BI 771716
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDR-Life Achieves Fourth Milestone with Boehringer in Phase 1 Geographic Atrophy Trial
Details : BI 771716 is an antibody fragment-based compound, which is being evaluated in the early-stage clinical trial studies for the treatment of patients with geographic atrophy.
Brand Name : BI 771716
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : BI 771716
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDR-Life Unveils Results on T-Cell Engagers Targeting Hard-to-Treat Solid Tumors at AACR
Details : It is a T cell receptor (TCR) gene therapy, which is being evaluated in preclinical trials for the treatment of patients with KK-LC-1/HLA-A*01-positive cancer.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 05, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDR-Life Receives FDA Clearance for IND of CDR404 for Solid Tumor Treatment
Details : CDR404 is a bispecific MAGE-A4 T-cell engager based on M-gager® technology, currently in preclinical studies for lung, bladder, and esophageal cancers.
Brand Name : CDR404
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 23, 2024
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : BI 771716
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BI 771716, developed with technology licensed from CDR-Life, is a highly specific antibody fragment of reduced size, enabling an optimized penetration through all retinal layers to the most critical target site driving GA disease pathology.
Brand Name : BI 771716
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 06, 2023
Lead Product(s) : BI 771716
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Sponsor : Boehringer Ingelheim GmbH
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CDR202
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $487.7 million
Deal Type : Collaboration
Details : Under the collaboration, the partners will advance CDR-Life’s preclinical antibody fragment-based therapeutic including CDR202, targeting a key pathway in geographic atrophy (GA).
Brand Name : CDR202
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 02, 2023
Lead Product(s) : CDR202
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $487.7 million
Deal Type : Collaboration
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Jeito Capital
Deal Size : $76.0 million
Deal Type : Series A Financing
CDR-Life Announces $76 Million Raised in Series A Funding
Details : Proceeds from financing will advance CDR404 through potential clinical proof-of-concept readout as well as expansion of the pipeline leveraging M-gager® technology for targeting intracellular antigens positioned to deliver unparalleled specificity and a...
Brand Name : CDR404
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 13, 2022
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Jeito Capital
Deal Size : $76.0 million
Deal Type : Series A Financing
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
CDR-Life to Present at the American Association for Cancer Research 2022 Annual Meeting
Details : CDR404, a first-in-class dual MAGE-A4 T-cell engager, results from the pre-clinical proof-of-concept, demonstrated that antibody targeting a highly cancer-specific intracellular protein is highly effective in recruiting immune system to specifically erad...
Brand Name : CDR404
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 22, 2022
Lead Product(s) : CDR404
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Antibody fragment-based therapeutics
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $494.0 million
Deal Type : Licensing Agreement
Details : Together, with Boehringer Ingelheim’s expertise in the therapeutic development of biologics and CDR-Life’s strong know-how in antibody engineering, the two companies will progress CDR-Life’s preclinical candidate, with the aim to preserve sight for...
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
May 13, 2020
Lead Product(s) : Antibody fragment-based therapeutics
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $494.0 million
Deal Type : Licensing Agreement
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