[{"orgOrder":0,"company":"CDR Life","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Antibody fragment-based therapeutics","moa":"","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"CDR Life","amount2":0.48999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0.48999999999999999,"dosageForm":"","sponsorNew":"CDR Life \/ Boehringer Ingelheim","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Boehringer Ingelheim"},{"orgOrder":0,"company":"CDR Life","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"CDR404","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CDR Life \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Not Applicable"},{"orgOrder":0,"company":"CDR Life","sponsor":"Jeito Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Series A Financing","leadProduct":"CDR404","moa":"Cytotoxic T-Cell","graph1":"Oncology","graph2":"Preclinical","graph3":"CDR Life","amount2":0.080000000000000002,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0.080000000000000002,"dosageForm":"","sponsorNew":"CDR Life \/ Jeito Capital","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Jeito Capital"},{"orgOrder":0,"company":"CDR Life","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2023","type":"Collaboration","leadProduct":"CDR202","moa":"","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"CDR Life","amount2":0.48999999999999999,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0.48999999999999999,"dosageForm":"","sponsorNew":"CDR Life \/ Boehringer Ingelheim GmbH","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"CDR Life","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"CDR404","moa":"","graph1":"Oncology","graph2":"IND Enabling","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CDR Life \/ Not Applicable","highestDevelopmentStatusID":"5","companyTruncated":"CDR Life \/ Not Applicable"},{"orgOrder":0,"company":"CDR Life","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2023","type":"Not Applicable","leadProduct":"BI 771716","moa":"","graph1":"Ophthalmology","graph2":"Phase I","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CDR Life \/ Boehringer Ingelheim GmbH","highestDevelopmentStatusID":"6","companyTruncated":"CDR Life \/ Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"CDR Life","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Undisclosed","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CDR Life \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Not Applicable"},{"orgOrder":0,"company":"CDR Life","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"BI 771716","moa":"","graph1":"Ophthalmology","graph2":"Phase I","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"CDR Life \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"CDR Life \/ Not Applicable"},{"orgOrder":0,"company":"CDR Life","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"CDR813","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"CDR Life","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"CDR Life \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"CDR Life \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by CDR Life

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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : CDR813 is a highly potent and selective TCE candidate targeting tumors expressing PRAME (preferentially expressed antigen in melanoma) in HLA-A*02:01 patients.

                          Brand Name : CDR813

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 25, 2024

                          Lead Product(s) : CDR813

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : BI 771716 is an antibody fragment-based compound, which is being evaluated in the early-stage clinical trial studies for the treatment of patients with geographic atrophy.

                          Brand Name : BI 771716

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 30, 2024

                          Lead Product(s) : BI 771716

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : It is a T cell receptor (TCR) gene therapy, which is being evaluated in preclinical trials for the treatment of patients with KK-LC-1/HLA-A*01-positive cancer.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          April 05, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : CDR404 is a bispecific MAGE-A4 T-cell engager based on M-gager® technology, currently in preclinical studies for lung, bladder, and esophageal cancers.

                          Brand Name : CDR404

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 23, 2024

                          Lead Product(s) : CDR404

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : BI 771716, developed with technology licensed from CDR-Life, is a highly specific antibody fragment of reduced size, enabling an optimized penetration through all retinal layers to the most critical target site driving GA disease pathology.

                          Brand Name : BI 771716

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          December 06, 2023

                          Lead Product(s) : BI 771716

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Under the collaboration, the partners will advance CDR-Life’s preclinical antibody fragment-based therapeutic including CDR202, targeting a key pathway in geographic atrophy (GA).

                          Brand Name : CDR202

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 02, 2023

                          Lead Product(s) : CDR202

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : $487.7 million

                          Deal Type : Collaboration

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                          07

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Proceeds from financing will advance CDR404 through potential clinical proof-of-concept readout as well as expansion of the pipeline leveraging M-gager® technology for targeting intracellular antigens positioned to deliver unparalleled specificity and a...

                          Brand Name : CDR404

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 13, 2022

                          Lead Product(s) : CDR404

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Jeito Capital

                          Deal Size : $76.0 million

                          Deal Type : Series A Financing

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                          08

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : CDR404, a first-in-class dual MAGE-A4 T-cell engager, results from the pre-clinical proof-of-concept, demonstrated that antibody targeting a highly cancer-specific intracellular protein is highly effective in recruiting immune system to specifically erad...

                          Brand Name : CDR404

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 22, 2022

                          Lead Product(s) : CDR404

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Together, with Boehringer Ingelheim’s expertise in the therapeutic development of biologics and CDR-Life’s strong know-how in antibody engineering, the two companies will progress CDR-Life’s preclinical candidate, with the aim to preserve sight for...

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          May 13, 2020

                          Lead Product(s) : Antibody fragment-based therapeutics

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : $494.0 million

                          Deal Type : Licensing Agreement

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