Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Cellectar Fully Exercises Tranche A Warrants, Raising $44.1 Million
Details : Net proceeds will fund CLR 131 (iopofosine I-131), designed for targeted iodine-131 delivery to cancer cells, being evaluated for Waldenstrom Macroglobulinemia and other cancers.
Brand Name : CLR 131
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 25, 2024
Lead Product(s) : 225Ac-CLR 121225
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Cellectar Broadens Pipeline with Targeted Alpha Therapy for Solid Tumors
Details : CLR 121225 (225Ac-CLR-121225) is an actinium-labeled phospholipid ether. It is a novel α-emitting phospholipid radiotherapeutic conjugate. It is being evaluated for refractory pancreatic cancer.
Brand Name : CLR 121225
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 16, 2024
Lead Product(s) : 225Ac-CLR 121225
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Cellectar Partners with MiBA to Advance Waldenstrom's Macroglobulinemia Treatment
Details : The partnership aims to advance the treatment of Waldenstrom's macroglobulinemia with Cellectar’s iopofosine I 131, a novel phospholipid radiotherapeutic conjugate.
Brand Name : CLR 131
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 11, 2024
Cellectar Announces Positive Data Achieving Primary Endpoint in Waldenstrom’s Study
Details : CLR 131 (Iopofosine I 131) is a potential first-in-class, targeted radiotherapy candidate, which is under phase 2 clinical development for relapsed/refractory Waldenstrom’s macroglobulinemia.
Brand Name : CLR 131
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 08, 2024
Details : I-131-CLR1404 (Iopofosine I 131) is a small-molecule Phospholipid Drug Conjugate™ designed to provide targeted delivery of iodine-131 (radioisotope) directly to cancer cells, while limiting exposure to healthy cells.
Brand Name : I-131-CLR1404
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 13, 2022
Lead Product(s) : Iopofosine I-131
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Details : The grant will be used to support and accelerate the ongoing pivotal study of iopofosine I-131 (CLR 131) in Waldenstrom’s macroglobulinemia (WM) patients who have received at least two prior lines of therapy.
Brand Name : CLR-131
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 18, 2021
Lead Product(s) : Iopofosine I-131
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : National Cancer Institute
Deal Size : $2.0 million
Deal Type : Funding
Lead Product(s) : Iopofosine I-131
Therapeutic Area : Oncology
Study Phase : Phase II
Recipient : Evergreen Theragnostics
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement with Evergreen provides long term commercial supply of iopofosine I-131 and supply of clinical study material for Cellectar’s pivotal study in Waldenstrom’s macroglobulinemia (WM) as well as ongoing Phase 1 and Phase 2 clinical studies.
Brand Name : CLR-131
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 16, 2021
Lead Product(s) : Iopofosine I-131
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Evergreen Theragnostics
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Phospholipid Drug Conjugates
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : IntoCell
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Cellectar Announces Expansion of Ongoing Collaboration Agreement with IntoCell Inc
Details : The collaboration focuses on combining IntoCell’s validated novel Ortho-Hydroxy Protected Aryl Sulfate (OHPAS) linker chemistry with Cellectar’s validated novel targeting platform, phospholipid ethers (PLEs) to develop new PDCs.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 13, 2021
Lead Product(s) : Phospholipid Drug Conjugates
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : IntoCell
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Details : Cellectar is conducting pivotal trial evaluating CLR 131 in Waldenstrom’s macroglobulinemia patients that have failed or had a suboptimal response to a Bruton’s tyrosine kinase inhibitor in U.S and intends to expand the trial to additional US and int...
Brand Name : I-131-CLR1404
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 27, 2021
Cellectar Granted Composition of Matter and Use Patent in Europe for CLR 131
Details : Patent covers the phospholipid ether (PLE) delivery vehicle combined with I-131 and I-125.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 14, 2020
LOOKING FOR A SUPPLIER?